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Philippines stamps out polio outbreak after a 16-month drive

COVID-19 and vaccine hesitancy did not stop the Philippines from stamping out a polio outbreak in a 16-month drive that ended June 2021, a feat commended by WHO and UNICEF.

28 Jun 2021

Could the activation of FcγRIII/CD16 by anti-spike SARS-CoV-2 antibodies independently determine COVID-19 severity?

A team of scientists from Germany recently investigated whether hyperactivation of immune receptors that recognize the Fc part of an IgG molecule (FcγR) can lead to immunopathologic changes in coronavirus disease 2019 (COVID-19) patients. They have observed that hyperactivation of FcγRIII (CD16) by proinflammatory IgG antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can significantly contribute to COVID-19 related immunopathology.

28 Jun 2021

People living with HIV/AIDS more likely to have suicidal thoughts and die from suicide

A new study by researchers at Penn State College of Medicine indicates that people living with human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) - approximately 38 million worldwide - are more likely to have suicidal thoughts and die from suicide than members of the general population.

28 Jun 2021

Novel face mask can diagnose Covid-19 in 90 minutes

Engineers at MIT and Harvard University have designed a novel face mask that can diagnose the wearer with Covid-19 within about 90 minutes. The masks are embedded with tiny, disposable sensors that can be fitted into other face masks and could also be adapted to detect other viruses.

28 Jun 2021

Gene variant in African Americans contributes to unnecessary bone marrow biopsies

A gene variant that lowers white blood cell levels and is common in individuals with African ancestry contributes to unnecessary bone marrow biopsies, according to a study published June 28 in JAMA Internal Medicine.

28 Jun 2021

Researchers develop engineered yeast probiotic for treatment of inflammatory bowel disease

The world of microbes living in the human gut can have far-reaching effects on human health. Multiple diseases, including inflammatory bowel disease (IBD), are tied to the balance of these microbes, suggesting that restoring the right balance could help treat disease.

28 Jun 2021

UK study finds SARS-CoV-2 antibodies in domestic cats and dogs

Researchers analyzed sera from pet cats and dogs and found them to have developed antibodies against the virus later on during the COVID-19 pandemic. These findings suggest that viral prevalence among the human populations could have led to the pets becoming infected.

28 Jun 2021

Study associates higher antibody titers with naïve B cells post-mRNA vaccination

Researchers compared peripheral blood mononuclear cells in people with high and low antibody titers after two doses of the Pfizer/BioNTech (BNT162b2) mRNA vaccine. They found a positive correlation between naïve B cells present before vaccination and high antibody titers.

28 Jun 2021

What have been the main drivers of COVID-19's rapid spread in Brazil?

New research suggests that if a lockdown had been imposed earlier on in superspreader cities like São Paulo, mandatory road traffic restrictions had been enforced, and ICU beds had been allocated more equitably across geographical regions, Brazil’s experience of the COVID-19 pandemic might have been mitigated.

28 Jun 2021

Study finds minimal SARS-CoV-2 viral load in vaginal secretions

The virus has also been observed to be present in blood, urine, feces, and tears, though not in semen. Vaginal secretions have not been consistently shown to be positive for the virus in most studies. The authors of a new study in the Journal of Clinical Medicine affirm that the presence of the virus in the vagina is rare, irrespective of pregnancy.

28 Jun 2021

Resting heart rate variability predicts emotional resilience during COVID-19 restrictions

An interesting new study available as a preprint on the medRxiv* server suggests that vagally-mediated heart rate variability (vmHRV) is a physiological marker of resilience to stress by indicating how well an individual handles the emotions when faced with changes in the surroundings.

28 Jun 2021

Could microalgae-derived antiviral compounds combat SARS-CoV-2 and other viruses?

A new review article published in the journal Antibiotics reports the presence of a large number of bioactive compounds in microalgae that target chemical structures present only in their structure.

28 Jun 2021

Vaccines and drugs must be adapted to combat emerging SARS-CoV-2 variants, says study

A new review of the emerging variants of concern (VOCs) of the SARS-CoV-2, which has caused the COVID-19 pandemic, shows that there is a major need to constantly re-evaluate the utility of existing therapeutics and vaccines against the virus and to develop new ones.

28 Jun 2021

Achieving gender equality within global health

News-Medical spoke to Dr. Claire Bayntun about her incredible career in global health, and how we can achieve gender equality within healthcare settings.

28 Jun 2021

COVID-19 patients with traumatic injuries have six times higher risk of complications, death

In addition to sickening and taking the lives of millions across the globe, COVID-19 complicated patient care in a range of less-direct ways, from increased incidence of heart attacks to decreased cancer screenings.

28 Jun 2021

Study examines effect of sorafenib in patients with advanced hepatocellular carcinoma

Oncotarget published "Insulin-like growth factor 1/Child-Turcotte-Pugh composite score as a predictor of treatment outcomes in patients with advanced hepatocellular carcinoma treated with sorafenib" which reported that this study investigated the association of the IGF/CTP score with overall survival and progression-free survival of HCC patients treated with sorafenib.

28 Jun 2021

Promising immunotherapy uses cancer-killing cells to destroy malignant tumors

Researchers at McMaster University have developed a promising new cancer immunotherapy that uses cancer-killing cells genetically engineered outside the body to find and destroy malignant tumors.

28 Jun 2021

Anti-cancer prodrug can benefit cancer patients

Unlike conventional cancer drugs that attack and kill cancer cells directly, anti-cancer immunotherapy, which kills cancer cells by strengthening the body's immunity, is a novel type of cancer treatment currently attracting increased attention. Unfortunately, a minority of cancer patients who have some degree of pre-existing immunity only benefit from anti-cancer immunotherapy.

28 Jun 2021

Antagonism of glucocorticoid receptors promotes apoptosis in solid tumor cells

Oncotarget published "Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells" which reported that to guide studies in cancer patients, relacorilant, an investigational selective GR modulator that antagonizes cortisol activity, was assessed in various tumor types, with multiple cytotoxic combination partners, and in the presence of physiological cortisol concentrations.

28 Jun 2021

Study explores the potential role of gene polymorphisms in pathogenesis of prostate cancer

Oncotarget published "The presence of polymorphisms in genes controlling neurotransmitter metabolism and disease prognosis in patients with prostate cancer: a possible link with schizophrenia" reported that polymorphisms of neurotransmitter metabolism genes were studied in patients with prostate cancer (PC) characterized by either reduced or extended serum prostate-specific antigen doubling time corresponding to unfavorable and favorable disease prognosis respectively.

28 Jun 2021

Medical News

Philippines stamps out polio outbreak after a 16-month drive

Could the activation of FcγRIII/CD16 by anti-spike SARS-CoV-2 antibodies independently determine COVID-19 severity?

People living with HIV/AIDS more likely to have suicidal thoughts and die from suicide

Novel face mask can diagnose Covid-19 in 90 minutes

Gene variant in African Americans contributes to unnecessary bone marrow biopsies

Researchers develop engineered yeast probiotic for treatment of inflammatory bowel disease

UK study finds SARS-CoV-2 antibodies in domestic cats and dogs

Study associates higher antibody titers with naïve B cells post-mRNA vaccination

What have been the main drivers of COVID-19's rapid spread in Brazil?

Study finds minimal SARS-CoV-2 viral load in vaginal secretions

Resting heart rate variability predicts emotional resilience during COVID-19 restrictions

Could microalgae-derived antiviral compounds combat SARS-CoV-2 and other viruses?

Vaccines and drugs must be adapted to combat emerging SARS-CoV-2 variants, says study

Achieving gender equality within global health

COVID-19 patients with traumatic injuries have six times higher risk of complications, death

Study examines effect of sorafenib in patients with advanced hepatocellular carcinoma

Promising immunotherapy uses cancer-killing cells to destroy malignant tumors

Anti-cancer prodrug can benefit cancer patients

Antagonism of glucocorticoid receptors promotes apoptosis in solid tumor cells

Study explores the potential role of gene polymorphisms in pathogenesis of prostate cancer

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

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