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Can control theory explain differences in virulence and transmission of SARS-CoV-2?

A new study discusses variations in viral pathogenicity and in transmission, which are responsible for asymptomatic infection and for superspreading events. The ability to understand this would open the way to understand how this virus behaves the way it does, in terms of its virulence, its spread, and its emergent variants of concern.

28 Apr 2021

COVID-19 donor antibodies show broad cross-reactivity against SARS-CoV-2 variants and related viruses

A new study reports on a set of antibodies from COVID-19 donor serum, which seems to be cross-reactive across multiple Sarbecoviruses, including the very similar SARS-CoV-2, SARS-CoV and Middle East Respiratory Syndrome (MERS)-CoV.

28 Apr 2021

Albumedix extends research collaboration with Cobra Biologics to optimize viral vector manufacturing

Albumedix Ltd. ('Albumedix'), an emerging leader in the enablement of advanced therapies and recognized global leader in recombinant human albumin (rHA) has today announced an extension to its research collaboration with Cobra Biologics, the gene therapy division of Cognate BioServices, a Charles River Laboratories International, Inc. company.

From Albumedix Ltd. 28 Apr 2021

Peptide nucleocapsid vaccine candidate elicits protective T cell immunity against SARS-CoV-2 in vivo

A new study describes a synthetic peptide used as a platform to generate protective adaptive cellular immunity to the virus in rhesus macaques, which are the gold standard for preclinical testing in humans.

28 Apr 2021

Ohio’s Amish suffered a lot from Covid, but vaccines are still a hard sell

The Amish communities of northeastern Ohio engage in textbook communal living. Families eat, work and go to church together, and through the pandemic, mask-wearing and physical distancing have been spotty. That has meant that these communities bore a high rate of infection and death.

28 Apr 2021

You don’t have to suffer to benefit from Covid vaccination — but some prefer it

If you think vaccination is an ordeal now, consider the 18th-century version. After having pus from a smallpox boil scratched into your arm, you would be subject to three weeks of fever, sweats, chills, bleeding and purging with dangerous medicines, accompanied by hymns, prayers and hell-fire sermons by dour preachers.

28 Apr 2021

Brains of individuals with autism successfully encode facial emotions, study reveals

A study that tested neural activity in the brains of individuals with Autism Spectrum Disorder (ASD) reveals that they successfully encode facial emotions in their neural signals – and they do so about as well as those without ASD.

28 Apr 2021

SARS-CoV-2 recruits heme metabolites in antibody evasion

A research paper recently published in the journal Science Advances by Cherepanov et al. (April 22nd, 2021) demonstrated that the NTD binds to biliverdin, a product of heme catabolism, leading to enhanced antibody escape at physiologically relevant concentrations.

28 Apr 2021

Leveraging vibrations and ultrasound waves to diagnose, treat brain ailments

A team of engineering researchers at the Georgia Institute of Technology hopes to uncover new ways to diagnose and treat brain ailments, from tumors and stroke to Parkinson's disease, leveraging vibrations and ultrasound waves.

28 Apr 2021

Eosinophils modify the respiratory barrier during influenza A infection, shows study

For the first time in published literature, Le Bonheur Children's Hospital and University of Tennessee Health Science Center (UTHSC) researchers showed that a variety of white blood cells known as eosinophils modify the respiratory barrier during influenza A (IAV) infection, according to a recent paper in the journal Cells.

28 Apr 2021

Horizontal transmission route is responsible for HTLV-1 uveitis

Human T-cell lymphotropic virus type-1 (HTLV-1) is a retrovirus similar to human immunodeficiency virus (HIV) and has mostly been thought to be transmitted vertically (mother-to-child), or horizontally (sexually or parenterally (e.g. via blood transfusion)).

28 Apr 2021

Intramuscular droperidol more effective than other drugs for treatment of acute agitation in the ED

In a randomized, double-blind trial of patients with acute undifferentiated agitation in the emergency department, droperidol was more effective for sedation and was associated with fewer episodes of respiratory depression than lorazepam or either dose of ziprasidone.

28 Apr 2021

Scientists design 'smart' cellular biosensors for detecting SARS-CoV-2 spike

New research led by Hana El-Samad of the University of California, San Francisco, and the Chan-Zuckerberg Biohub confirmed the beneficial use of an antiviral therapeutic called SARSNotch, which uses a combination of the SynNotch platform and de-novo designed protein binders. SARSNotch uses sentinel T cells to detect and mount a genetic response toward the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

28 Apr 2021

Municipalities with low socioeconomic status in Greater Santiago have higher COVID-19 mortality

People up to age 40 living in economically depressed municipalities in the Greater Santiago, Chile, metropolitan area were three times more likely to die as a result of the infection than their counterparts in wealthier areas, researchers report in the journal Science.

28 Apr 2021

Why do we lose our sense smell/taste with COVID?

The angiotensin-converting enzyme 2 (ACE2) enzyme attached to the membranes of cells is the entry point for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They are abundantly found all over the body and most prominently in the lungs and nose.

28 Apr 2021

ASPS survey reveals COVID-19's impact and patient demand for plastic surgery

The American Society of Plastic Surgeons (ASPS) - the world's largest plastic surgery organization, representing nearly 8,000 members - today released the 2020 results of the organization's annual procedure survey coupled with national consumer research reflecting trends during the COVID-19 era to help predict what 2021 will bring.

28 Apr 2021

Neonates exposed to SARS-CoV-2 can sustain adverse health outcomes

The incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission from mothers to newborns appears low and may be linked to biological as well as social factors. However, studies focusing on the factors associated with neonatal viral testing outcomes.

27 Apr 2021

SARS-CoV-2 virus neutralized with half-second exposure to very high temperature

As reported in the journal Biotechnology and Bioengineering, the team from Texas A&M University developed a simple fluidics system that measures the sub‐second heat inactivation of coronaviruses.

27 Apr 2021

Clinical trial to test existing antibiotic for treating serious S. aureus infections begins

A clinical trial to test the antibiotic dalbavancin for safety and efficacy in treating complicated Staphylococcus aureus (S. aureus) bacteremia has begun.

27 Apr 2021

Pfizer-BioNTech (BNT162b2) vaccine successfully curbs COVID-19 in Israel

Researchers in Israel have shown that three national programs established by the Israeli government have successfully reduced cases of severe coronavirus disease 2019 (COVID-19) and death caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

27 Apr 2021

Medical News

Can control theory explain differences in virulence and transmission of SARS-CoV-2?

COVID-19 donor antibodies show broad cross-reactivity against SARS-CoV-2 variants and related viruses

Albumedix extends research collaboration with Cobra Biologics to optimize viral vector manufacturing

Peptide nucleocapsid vaccine candidate elicits protective T cell immunity against SARS-CoV-2 in vivo

Ohio’s Amish suffered a lot from Covid, but vaccines are still a hard sell

You don’t have to suffer to benefit from Covid vaccination — but some prefer it

Brains of individuals with autism successfully encode facial emotions, study reveals

SARS-CoV-2 recruits heme metabolites in antibody evasion

Leveraging vibrations and ultrasound waves to diagnose, treat brain ailments

Eosinophils modify the respiratory barrier during influenza A infection, shows study

Horizontal transmission route is responsible for HTLV-1 uveitis

Intramuscular droperidol more effective than other drugs for treatment of acute agitation in the ED

Scientists design 'smart' cellular biosensors for detecting SARS-CoV-2 spike

Municipalities with low socioeconomic status in Greater Santiago have higher COVID-19 mortality

Why do we lose our sense smell/taste with COVID?

ASPS survey reveals COVID-19's impact and patient demand for plastic surgery

Neonates exposed to SARS-CoV-2 can sustain adverse health outcomes

SARS-CoV-2 virus neutralized with half-second exposure to very high temperature

Clinical trial to test existing antibiotic for treating serious S. aureus infections begins

Pfizer-BioNTech (BNT162b2) vaccine successfully curbs COVID-19 in Israel

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

The importance of ketones from a clinical and medical perspective

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