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Integrin b3 and ACE2 linked by short linear motifs enabling endocytosis and autophagy of SARS-CoV-2

A new study by Uppsala University researchers published on the preprint server bioRxiv in October 2020 shows possible links between the angiotensin-converting enzyme 2 (ACE2) host cell receptors for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the entry of viral particles into the cell via endocytosis and autophagy.

12 Oct 2020

Using expressive writing techniques to help Covid-19 healthcare workers overcome trauma

A project developed by a Kingston School of Art London researcher that aims to help people overcome trauma through expressive writing techniques is to be offered to healthcare professionals around the world who are on the front line of the Covid-19 crisis.

12 Oct 2020

Report: Nearly two million babies are stillborn annually

Nearly two million babies are stillborn every year, with 84 per cent of cases occurring in low- and lower middle-income countries, says an 8 October report by WHO, UNICEF and partners.

12 Oct 2020

Sub-second heat inactivation of coronavirus

Three coronaviruses (CoVs) have caused global outbreaks within the past 20 years, and with the COVID19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) still ongoing, methods that can rapidly inactivate these viruses can play critical roles in ensuring public safety and safeguarding personal health.

12 Oct 2020

Stem cells that repair broken bones can also generate arthritic bone spurs

The same stem cells that heal broken bones can also generate arthritic bone spurs called osteophytes, according to a new study in the Annals of the Rheumatic Diseases.

12 Oct 2020

Scientists develop new method for detecting TBI at the point of care

A method for detecting traumatic brain injury at the point of care has been developed by scientists at the University of Birmingham.

12 Oct 2020

Even mild fatty liver disease associated with higher risk of all-cause mortality

Non-alcoholic fatty liver disease, NAFLD, affects nearly one in four adults in Europe and the U.S. Earlier research has demonstrated an increased risk of death in patients with NAFLD and advanced fibrosis or cirrhosis.

12 Oct 2020

Italian research shows low transmission of SARS-CoV-2 within schools

A team of scientists from Italy has recently conducted a study to investigate the incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among students attending Italian schools after reopening after COVID-19 lockdown. The findings reveal that the transmission of SARS-CoV-2 is low among younger students. The study is published on the medRxiv preprint server.

12 Oct 2020

Universal facemask use could prevent hundreds of thousands of COVID-19 deaths

The Institute for Health Metrics and Evaluation (IHME) COVID-19 Forecasting team has advised that universal mask-wearing during the coronavirus disease 2019 (COVID-19) pandemic could save hundreds of thousands of lives and delay the need for mitigation measures such as stay-at-home policies.

12 Oct 2020

Study provides a new depth of resolution to understand single gene disorders

Traditionally, geneticists divide disorders into "simple," where a single gene mutation causes disease, or complex, where mutations in many genes contribute modest amounts. A new study suggests that the truth is somewhere in between.

12 Oct 2020

Newly identified coronavirus epitopes induce robust antibody responses

Researchers at the University of Wisconsin-Madison have conducted a study showing that infection with severe acute respiratory syndrome coronavirus 2 (SARS-C0V-2) triggers robust immune responses to epitopes across the full viral proteome.

12 Oct 2020

COVID-19 susceptibility is independent of age, research shows

Scientists have estimated that the age of an individual does not indicate how likely they are to be infected by SARS-CoV-2. However, development of symptoms, progression of the disease, and mortality are age-dependent.

12 Oct 2020

COVID-19-positive mothers rarely transmit the virus to their newborns

Mothers with SARS-CoV-2 infection rarely transmit the virus to their newborns when basic infection-control practices are followed, according to a new study by researchers at Columbia University Irving Medical Center and NewYork-Presbyterian Morgan Stanley Children's Hospital.

12 Oct 2020

Optimizing allocation of future COVID-19 vaccine can double effectiveness

In anticipation of coronavirus disease (COVID-19) vaccine deployment, the Australian and US researchers utilized an age-structured mathematical model to appraise the potential benefits of optimizing age-specific dose allocation for suppressing SARS-CoV-2 transmission – and reaffirmed the notion that vaccination alone may be inadequate to achieve herd immunity in some settings. The study is currently available on the medRxiv* preprint server.

12 Oct 2020

Scientists develop new type of precise therapeutic vaccine against leukemia

Exploration of new leukemia antigens and construction of appropriate delivery systems using FDA-approved material are important strategies for developing leukemia vaccines for clinic use.

12 Oct 2020

Nasal spray COVID-19 vaccine shows promising results in mice

With promising vaccines comes a new candidate that has shown potent pre-clinical immune responses. The vaccine, developed by scientists at the University of Alabama at Birmingham (UAB), induced a potent T-cell response at the mucus layer of the lungs, including killer CD8+ T-cells, which can recognize and kill virally infected cells.

12 Oct 2020