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Deciphering the role of RET in cancer and breakthroughs in targeted treatments

Xueqing Hu , Ujjwol Khatri , Tao Shen , and Jie Wu, at University of Oklahoma Health Sciences Center, USA, provides a comprehensive review of the role of the RET (REarranged during Transfection) receptor tyrosine kinase in cancer development and the advancements in RET-targeted cancer therapies.

19 Jul 2024

Ginseng genome unlocks secrets of medicinal benefits

A landmark study has successfully decoded the complete ginseng genome, unveiling the genetic mechanisms that govern saponin biosynthesis. This detailed genetic map illuminates the evolutionary and metabolic pathways of Panax ginseng, a staple in traditional medicine. This pivotal discovery promises to drive forward breeding initiatives and augment the plant's medicinal qualities, unlocking new possibilities for therapeutic applications.

19 Jul 2024

New insights into modified nucleoside synthesis

The genetic information on DNA is transcribed into messenger RNA (mRNA) and translated to the amino acid sequence by transfer RNA (tRNA) on the ribosome. Modified nucleosides within RNA are involved in maintaining and regulating the protein synthesis system.

19 Jul 2024

Medical debt doubles risk of skipping mental health care for depression and anxiety

Medical debt is significantly more prevalent among adults with depression or anxiety compared to adults without these mental disorders, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health. Among adults with depression or anxiety, those with medical debt were twice as likely to report having delayed or forgone mental health care in the previous 12 months compared to those without medical debt.

19 Jul 2024

Scurvy on the rise in the United States: Pediatric cases triple in five years

Researchers found that pediatric scurvy cases tripled from 2016 to 2020, highlighting a significant rise in incidence, particularly among low-income, male, and autistic children.

19 Jul 2024

Sequence Biotech LLC assumes full distribution of Sorenson Benchtop Pipettor

Sequence Biotech LLC is excited to announce that we have taken over the full distribution of our flagship product, the Precision Series 96-channel benchtop pipettor, previously branded as the "Sorenson Benchtop Pipettor."

From Sequence Biotech 19 Jul 2024

Study examines brain activity and time perception over minutes and hours

Ever hear the old adage that time flies when you're having fun? A new study by a team of UNLV researchers suggests that there's a lot of truth to the trope.

19 Jul 2024

Psilocybin reconfigures brain networks, showing potential for lasting therapeutic effects

Researchers found that high-dose psilocybin significantly disrupts brain functional connectivity, particularly in the default mode network, with lasting effects linked to therapeutic benefits.

18 Jul 2024

Novel peptide PEPITEM shows promise in fighting 'inflammaging'

A naturally occurring peptide called PEPITEM could potentially rejuvenate the immune response in older individuals and protect against 'inflammaging', which is widely believed to be the root cause of many age-related diseases.

18 Jul 2024

Extreme weather associated with higher rates of missed primary care appointments

Temperature extremes, becoming increasingly frequent due to growing global climate change, are associated with higher rates of missed primary care appointments, according to a recently published study from Drexel University researchers in the American Journal of Preventive Medicine.

18 Jul 2024

Rise of multidrug-resistant Salmonella strains in U.S. retail chicken meat

Salmonella infections are a major public health issue in the United States, causing over 1.3 million illnesses annually.

18 Jul 2024

Brain activity patterns can foreshadow 24-hour seizure risk

UCSF team discovers brain activity patterns that foreshadow seizures up to 24 hours before they occur.

18 Jul 2024

FDA approval of lifileucel: A milestone in tumor-infiltrating lymphocyte therapy for advanced melanoma

The recent U.S. Food and Drug Administration approval of lifileucel, the first commercial tumor-infiltrating lymphocyte (TIL) therapy for advanced melanoma, marks a significant breakthrough in cancer therapy.

18 Jul 2024

Vaccines and virus changes cut long COVID risk by 50%, but Omicron still poses a threat

Research shows that vaccination and temporal changes have significantly reduced the incidence of post-acute sequelae of SARS-CoV-2 infection, but a substantial risk remains during the Omicron era.

18 Jul 2024

Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice

Blocking IL-11 signaling extends lifespan and healthspan in mice, reducing age-related metabolic decline, frailty, and cancer incidence.

18 Jul 2024

Adopting a healthy lifestyle boosts life expectancy and cuts healthcare costs

Adopting five healthy lifestyle behaviors significantly extends life expectancy and reduces healthcare costs among Taiwanese adults, a new study finds.

18 Jul 2024

Exploring the expanding horizons of GLP-1 therapies beyond diabetes and obesity

In a Perspective, Daniel Drucker highlights the growing body of evidence that hints at the potential of glucagon-like peptide-1 (GLP-1)-based medications in treating conditions other than diabetes and obesity, including cardiovascular disease and neurodegenerative disorders.

18 Jul 2024

2023 Michigan Nurses Study reveals improved conditions, but burnout and abuse persist

Nurses in Michigan reported improved conditions in the 2023 Michigan Nurses Study compared to 2022, but burnout and understaffing remain high, and nearly half reported abuse in the workplace in the last year.

18 Jul 2024

Psilocybin and undisclosed ingredients found in popular mushroom gummies

Mushroom gummies being sold to promote brain function may contain the illegal hallucinogen psylocibin and other harmful ingredients not listed on the label, UVA Health experts are warning after five people – including a 3-year-old child – were sickened.

18 Jul 2024

Diverse genetic data illuminates health disparities across populations

The majority of genetic studies focus on people of European descent, which limits the understanding of how genes influence health in other populations.

18 Jul 2024