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GLP-1 drugs protect brain health by improving neurovascular function and reducing inflammation

Research highlights how GLP-1 receptor agonists may improve brain health by targeting the neurovascular unit, linking metabolic health to cognitive function. It suggests potential therapies for neurodegenerative diseases like Alzheimer's.

7 Oct 2024

Researchers uncover how senescent cells can both harm and heal in liver disease

Researchers developed novel genetic tools to trace, ablate, and manipulate p16^Ink4a+^ senescent cells, revealing their distinct roles in liver fibrosis and repair. Senescent macrophages promote fibrosis, while endothelial cells aid in tissue recovery.

7 Oct 2024

Low-income Medicare Advantage beneficiaries face barriers to dental, vision and hearing care

Lower-income adults with Medicare Advantage plans are more likely to have difficulty paying for dental, vision, and hearing services than higher-income beneficiaries - despite enrolling in plans that cover these benefits, according to a new study published in Health Affairs.

7 Oct 2024

New platform mimics immune interactions to boost cancer treatment

Imagine a world where your own immune cells are transformed into cancer-fighting superheroes.

7 Oct 2024

UMass Amherst researcher receives $2.2 million grant to study tuberculosis response

The National Institutes of Health recently awarded $2.2 million to Alissa Rothchild, assistant professor in the Department of Veterinary and Animal Sciences at the University of Massachusetts Amherst and an expert in tuberculosis (TB) immunology, to study the very first cells that respond to Mycobacterium tuberculosis (Mtb), the bacteria causing TB.

7 Oct 2024

Study highlights urgent need for improved pediatric emergency preparedness

Most U.S. hospital emergency departments - lacking staffing, training and equipment - are not fully prepared to care for children.

7 Oct 2024

Researchers discover effective treatment strategy for lethal glioblastoma

Glioblastoma (GBM) is the most lethal brain tumor, with a median survival rate of merely 12-16 months after diagnosis. Despite surgical, radiation and chemotherapy treatments, the two-year survival rate for GBM patients is less than 10%.

7 Oct 2024

British adults in midlife show better cardiovascular health than American counterparts

Rates of obesity, high blood pressure and high cholesterol are lower among British adults in their 30s and 40s compared to their counterparts in the US, according to a new study led by UCL researchers.

7 Oct 2024

Study reveals gaps in hepatitis C treatment among reproductive-aged women

Most pediatric cases of hepatitis C virus (HCV) infection are perinatal, meaning the virus is transmitted from birthing parent to child during pregnancy or birth, according to the Centers for Disease Control and Prevention.

7 Oct 2024

Innovative immunotherapy harnesses natural killer T cells to combat solid tumors

In the fight against cancer, chimeric antigen receptor T cell (CAR-T) therapy has achieved notable success in treating blood cancers. However, it has been largely ineffective against solid tumors.

7 Oct 2024

Researchers use AI to reveal sex-based differences in glioblastoma prognosis

For years, cancer researchers have noticed that more men than women get a lethal form of brain cancer called glioblastoma.

7 Oct 2024

New study confirms brain's waste-clearance pathways in humans

Scientists have long theorized about a network of pathways in the brain that are believed to clear metabolic proteins that would otherwise build up and potentially lead to Alzheimer's and other forms of dementia. But they had never definitively revealed this network in people - until now.

7 Oct 2024

Weekly injections of anti-obesity medications cost more than surgery

The cost of taking weekly injections of popular anti-obesity medications liraglutide (Saxenda) or semaglutide (Wegovy) exceeds that of metabolic and bariatric surgery in less than a year, according to a recent analysis published in the journal Surgical Endoscopy.

7 Oct 2024

Less is more in octreotide therapy for esophageal variceal hemorrhage

Researchers at the Medical University of South Carolina revealed the need to clarify current treatment guidelines for octreotide therapy following an esophageal variceal hemorrhage in a recent study from the American Journal of Medical Sciences.

7 Oct 2024

Study reveals diverse lengths of luteal phases in healthy women

The current expectation is that every ovulatory menstrual cycle will have a luteal phase (the time from egg released until the next flow) that lasts approximately 14 days.

7 Oct 2024

New insights on 5-fluorouracil's mechanism in different cancers

Study reveals the drug, 5-fluorouracil, acts differently in different types of cancer — a finding that could help researchers design better drug combinations.

7 Oct 2024

Early blood test can predict treatment response and survival prospects in metastatic prostate cancer

A blood test, performed when metastatic prostate cancer is first diagnosed, can predict which patients are likely to respond to treatment and survive the longest.

7 Oct 2024

BU professor recognized for excellence in the field of traumatic stress studies

Denise M. Sloan, PhD, professor of psychiatry at Boston University Chobanian & Avedisian School of Medicine and Senior Clinician Investigator, Behavioral Science Division, National Center for PTSD at VA Boston Healthcare System, has received the Robert Laufer, PhD Award for Outstanding Scientific Achievement from the International Society for Traumatic Stress Studies.

7 Oct 2024

Understanding behavioral changes in early dementia

When most people think of dementia, including Alzheimer's disease, they probably think of memory loss first.

7 Oct 2024

Epigenetic testing opens new doors for multiple myeloma treatment

Multiple myeloma is a type of blood cancer that appears mainly after the age of sixty. Its incidence, therefore, increases with the aging of the population.

7 Oct 2024