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  • Melanin Production Pathway
    Life Sciences - 26 Feb 2019
    Melanin is synthesised in cytoplasmic organelles called melanosomes, which reside in skin cells and hair follicles called melanocytes. This process is known as melanogenesis.
  • Fundamentals of Assay Design and Development
    Life Sciences - 26 Feb 2019
    This article describes important factors that must be taken into account when designing an assay for the life sciences, including drug development.
  • TGF-ß Signaling Pathway
    Life Sciences - 26 Feb 2019
    Transforming growth factor-ß (TGF-ß) signaling plays a vital role in regulating cell growth, differentiation, and development in a wide array of biological systems.
  • Biophotonics in Preclinical Studies
    Life Sciences - 26 Feb 2019
    The article describes the applications of biophotonics in preclinical studies, including FRET, biofluorescence and bioluminescence.
  • Does Allostery Exist in Monoclonal Antibodies?
    Life Sciences - 26 Feb 2019
    Allosteric interaction is particularly useful in the case of therapeutic biologics.
  • Flow Cytometry in Immunology
    Life Sciences - 14 Feb 2019
    Flow cytometry can be used to identify immuno-competent cells, quantify changes in expression of surface determinants, and to separate cell populations.
  • How are Host Cell Proteins Removed from Biopharmaceuticals?
    Life Sciences - 25 Jan 2019
    Removing host cell proteins is crucial, as these proteins are immunogenic and can thus compromise the integrity of the final product.
  • Eosinophil Function
    Life Sciences - 17 Jan 2019
    This article provides a brief overview of eosinophils; specialized cells of the immune system involved in anti-parasitic and inflammatory processes.
  • Amyloid Cascade Hypothesis
    Life Sciences - 8 Jan 2019
    The amyloid cascade hypothesis postulates that the initial event which triggers neuronal degradation in Alzheimer’s disease is enhanced amyloid-ß generation and aggregation.
  • Immunohistochemistry (IHC) Imaging Techniques
    Life Sciences - 3 Jan 2019
    Immunohistochemistry (IHC) is a technique that uses antibodies to visualize antigens in a sample through fluorescence or light microscopy.

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