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  • Tyrosine Kinase Inhibitors for Targeted Cancer Therapy
    Life Sciences - 28 May 2021
    Tyrosine kinase inhibitors, which reduce or eliminate the intensity of aberrant signals, are under thorough investigation as anticancer agents.
  • What is Preclinical Immunogenicity Assessment?
    Life Sciences - 3 May 2021
    Assessing the immunogenicity of any drug or therapeutic is essential to assessing efficacy and toxicity at the early stages of drug discovery.
  • Computational Modeling in Developmental Biology
    Life Sciences - 14 Apr 2021
    Computational modeling is increasingly used to improve understanding of complex systems such as those in developmental biology.
  • What are Morpholinos?
    Life Sciences - 12 Apr 2021
    A morpholino is a synthetic oligomer molecule that contains DNA bases on a methylene morpholine backbone. The name comes from morpholine oligomer.
  • What is the Global Preclinical Antibacterial Pipeline?
    Life Sciences - 23 Mar 2021
    Antibacterial resistance requires prompt global action to ensure that new antibacterial drugs are continuously developed against mutating strains of bacteria.
  • The Thermal Inactivation of SARS-CoV-2
    Life Sciences - 22 Mar 2021
    Viruses like SARS-CoV-2 are sensitive to thermal inactivation - temperature extremes that denature their constituent proteins and disable their function.
  • Multiple Cross Displacement Amplification
    Life Sciences - 19 Mar 2021
    Multiple cross displacement amplification (MCDA) is a nucleic acid amplification method commonly used for single-cell whole-genome DNA sequencing.
  • What are Endosomes?
    Life Sciences - 16 Mar 2021
    Endosomes are membrane-bound cytosolic vesicles with three major compartments namely early, late, and recycling endosomal compartments.
  • What is Pharmacodynamics?
    Life Sciences - 22 Feb 2021
    Pharmacodynamics, an essential concept within preclinical trials, studies the biological and physiological effects of drugs on an organism.
  • What are Neutrophil Extracellular Traps (NETs)?
    Life Sciences - 27 Jan 2021
    In addition to their role in fighting infections, neutrophil extracellular traps (NETs) have also emerged as a novel target for cancer therapy.

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