1440 nm wavelength beneficial in laser-assisted lipolysis for fat-disruption and tissue tightening

Cynosure, Inc. (Nasdaq: CYNO) today announced the presentation of a new study that demonstrates the clinical benefits of using a 1440 nm wavelength in laser-assisted lipolysis to disrupt fat tissue and tighten skin through tissue coagulation.  The study, led by Barry DiBernardo, M.D., Medical Director of New Jersey Plastic Surgery, is one of six Cynosure-related abstracts being presented this week at the 2010 American Society for Laser Medicine and Surgery (ASLMS) Annual Conference in Arizona.

Dr. DiBernardo's study evaluated the fat-disruption and tissue tightening that occurred in abdominal tissue treated with three separate wavelengths, including a 1440 nm laser.  The 1440 nm wavelength is the heart of Cynosure's Smartlipo Triplex, which was introduced in late 2009 as the newest member of Cynosure's family of workstations for laser-assisted lipolysis.  The Smartlipo Triplex is the highest-power laser energy device approved for fat removal by the U.S. Food and Drug Administration.

"At the same power and doses, tissue treated with the 1440 nm laser disrupted a larger area of fat tissue and demonstrated greater tissue tightening effects than the other wavelengths," Dr. DiBernardo said. "The conclusion that can be drawn from this research is that, in terms of the efficiency of fat removal and collagen remodeling, wavelength and laser energy play an integral role in patient outcomes.  In comparing these three unique wavelengths, the results from the 1440 nm laser demonstrated the most pronounced histological effects."

Michael Davin, president and chief executive officer of Cynosure, said, "The research presented at ASLMS further validates the investment we have made to increase the efficiency and performance of our Smartlipo technology with the addition of a 1440 nm wavelength.  The higher-powered laser, combined with enhancements such as SmartSense with ThermaGuide, which monitors and controls the flow of energy during laser-assisted lipolysis, gives our technology a strong competitive advantage in the marketplace.  Moreover, the study highlights a tenet of our corporate strategy – to support our brands with comprehensive scientific research."

Highlights from other Smartlipo-related abstracts being presented at ASLMS this week, include:

  • A 15-patient study conducted by John Millard, M.D. of the Millard Plastic Surgery Center in Colorado, who describes the successful use of the Smartlipo Triplex to not only improve body contour but also to highlight the three-dimensional muscular definition of areas including the arms, legs and abdomen.  "All outcomes were considered good or excellent, with adequate improvement in muscle definition," Dr. Millard reported.
  • Plastic surgeons Robert Gotkin, M.D. and Alberto Goldman, M.D., used the dual-wavelength Smartlipo MPX in a 20-patient study of women who underwent laser lipoabdominoplasty, a procedure to reduce the elevation of the abdominal flap.  All patients tolerated the surgery well, without major complications.  In comparison with the traditional and more invasive abdominoplasty procedure, the researchers concluded that the Multiplex procedure increased the contraction of skin and fat tissue, reduced the operative trauma associated with the procedure  and enhanced the patients' post-operative recovery experience.

"We are delighted with the results of these clinical studies, which highlight both the safety and efficacy of our device within potential expanded applications for our Smartlipo technology," Davin said.

In addition to the research on laser-assisted lipolysis, Cynosure's technology is featured in the following presentations at the ASLMS Annual Conference:

  • "A Prospective Study of the Improvement in Peri-Orbital Wrinkles and Eyebrow Elevation with a Novel Fractional CO2 Laser," Bruce E. Katz, M.D., Clinical Professor, Mt. Sinai School of Medicine, Director, JUVA Skin & Laser Center, Director, Cosmetic Surgery & Laser Clinic, Mt. Sinai Medical Center, New York, New York; Dvora Ancona, University of Pavia, Milan, Italy
  • Combined Therapy for Neck Rejuvenation: Fractional Non-Ablative Laser and Stabilized Hyaluronic Acid Based Gel of Non-Animal Origin: A Clinicopathologic Study with Special Attention Given to the Histology," Adriana Ribe, Natalia Ribe, Institut Dra Natalia Ribe, Barcelona, Spain
  • "Treatment of Carbon Tattoos in a Porcine Model with a Novel 758 nm, 500 Picosecond  Laser," Leonid Izikson, William Farinelli, Zeina Tannous, Fedrnanda Sakamoto, R. Rox Anderson, Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts

Source:

Cynosure, Inc.

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