BioCision LLC, the CoolPrep™ company, announced today that it has expanded its line of innovative benchtop sample handling tools with the launch of the CryoPrep System™, a modular complete solution for cell freezing procedures. The CryoPrep System provides ice-free cryo vial cooling, one-handed vial opening and closing, convenient portability of cell samples, and a controlled rate of cell freezing without the use of alcohol.
“The CryoPrep System is an ideal workstation set for ice-free cold cryo vial preparation and alcohol-free cell freezing, enhancing both efficiency and reproducibility”
Comprised of three precision-designed and -manufactured products - CoolBox™, CoolRack™ CFT and CoolCell™ - the CryoPrep System brings an additional element of versatility to BioCision's product line, by giving researchers a kit that can be used for a variety of cell freezing procedures. The compact design and ice-free cartridge technology of the CoolRack and CoolBox combination, for example, make them ideal for ice-free vial cooling in tissue culture hoods; yet dry ice, wet ice or liquid nitrogen may also be used as cooling sources.
"The CryoPrep System is an ideal workstation set for ice-free cold cryo vial preparation and alcohol-free cell freezing, enhancing both efficiency and reproducibility," said Dr. Tiina Sepp, vice president of new product development at BioCision. "Up to 30 cryo vial samples can be kept cold and dry, and opened or closed with one hand using the CoolRack CFT in the CoolBox. Once vials are prepared, the CoolCell provides alcohol-free -1oC/minute cell freezing in a -80°C freezer or dry ice locker. The elimination of alcohol means extremely high reproducibility and no maintenance."
The innovative CoolBox 30 System accommodates all 30-well CoolRacks and comes with a 2°C cartridge for ice-free cell sample cooling. The cartridges consist of a gel pack with a thermo-conductive alloy shell, which enables fast cooling and recharge in a standard -20ºC lab freezer, and provides continuous uniform temperature to all samples, eliminating "edge effect."
The 30-well CoolRack CFT features a unique well design that holds any 12.5mm cryo vial securely, for convenient one-handed opening and closing. CoolRack's high thermo-conductivity ensures rapid and reproducible equilibration of all wells to within 0.1ºC of the source temperature. In addition to eliminating temperature variability and providing stable, compact organization, CoolRack saves time and reduces user errors and accidents commonly associated with directly immersing tubes in dry ice, dry ice/alcohol slurries or liquid nitrogen.
CoolCell holds 12 screw cap 1ml or 2ml cryo tubes and features a solid thermal core for consistent, controlled -1ºC/minute cell freezing in a -80ºC freezer, without any alcohol. Requiring only minutes between freezing cycles and no maintenance, CoolCell is ideal for multiple batch freezing, ensuring identical freezing for all samples. The result is increased reproducibility and superior cell viability and function for scientific, clinical and diagnostic procedures.
Because of the low thermal mass design, CoolCell releases only one-third the heat given off by an alcohol-filled container. This means multiple CoolCells may be frozen simultaneously in a -80°C freezer without warming up the freezer or jeopardizing previously frozen samples.