Protein Metrics, Inc., a leading provider of software for rapid and thorough protein and peptide characterization, today announced the introduction of top-down analysis as part of the 2.0 release of its Byonic™ proteomics search engine. Building on Byonic's capability to provide sensitive, comprehensive peptide and protein identification from tandem mass spectrometry data, top-down analysis offers analysis on undigested proteins even above 50 kDa.
"We are thrilled to offer our customers this newest edition of Byonic in one unified piece of software and at no additional cost. We expect Byonic will become the software of choice for those who want a single tool to investigate undigested, partially digested, and fully digested protein samples," said Chris Becker, Ph.D., President and CEO of Protein Metrics. "Byonic's ability to identify modifications, variants, and intact glycopeptides on both undigested and digested proteins opens the R&D landscape in a fundamentally new way for both proteomics and biopharma scientists."
Byonic software offers wildcard search, Modification Fine Control™, and intact glycopeptide identification. Byonic results can be imported into Protein Metrics' Byologic® and Byomap™ software for biopharmaceutical development. Byonic can operate in stand-alone mode or as a node in Thermo Scientific's Proteome Discover™ software (versions 1.4 and 2.0).