Lightsheet microscopy is rapidly becoming an important tool for biological research. Among its strengths are high speed selective plane acquisition, low phototoxicity to samples and low photo bleaching of fluorophores. There are a variety of lightsheet schemes that enable researchers to answer new questions in live cell imaging at scales that range from individual cells to whole organisms.
Hamamatsu Photonics has been granted patents for their Lightsheet Readout Mode, which takes advantage of the rolling shutter readout in scientific CMOS cameras. Lightsheet Readout Mode is currently available in the ORCA-Flash4.0V2 camera. The patents place Hamamatsu's cameras in an ideal position regarding the lightsheet application, and Hamamatsu will move forward on enforcing their rights under these patents.
Japan: patented, patent no. JP05639670, JP05770958
United Kingdom: patented, patent no. GB2522793, GB2523012, GB2523263
Germany: patented, patent no. DE112014000195
United States: patents pending
China: patents pending