Retinal sheet transplants restore vision in blind rats

Sheets of fetal cells integrate into the retina and generate nearly normal visual activity in the brains of blind rats, reports new research published in JNeurosci.

Degeneration of the retina as a result of age or progressive eye disease damages the light-detecting cells necessary for accurate vision. Current treatments can only help protect existing cells from further damage and are ineffective during late stages of disease once these cells are gone. Retinal sheet transplants have been demonstrated in prior animal and human studies, but their ability to restore complex vision has not yet been assessed.

Measuring the response of neurons in the primary visual cortex, David Lyon and colleagues demonstrate rats with severe retinal degeneration that received donor cells became sensitive to various attributes of visual stimuli, including size, orientation, and contrast, as early as three months following surgery. The study represents an important step forward in combating age- and disease-related vision loss in human adults.

Citations

Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Society for Neuroscience. (2018, November 01). Retinal sheet transplants restore vision in blind rats. News-Medical. Retrieved on May 19, 2019 from https://www.news-medical.net/news/20181101/Retinal-sheet-transplants-restore-vision-in-blind-rats.aspx.

  • MLA

    Society for Neuroscience. "Retinal sheet transplants restore vision in blind rats". News-Medical. 19 May 2019. <https://www.news-medical.net/news/20181101/Retinal-sheet-transplants-restore-vision-in-blind-rats.aspx>.

  • Chicago

    Society for Neuroscience. "Retinal sheet transplants restore vision in blind rats". News-Medical. https://www.news-medical.net/news/20181101/Retinal-sheet-transplants-restore-vision-in-blind-rats.aspx. (accessed May 19, 2019).

  • Harvard

    Society for Neuroscience. 2018. Retinal sheet transplants restore vision in blind rats. News-Medical, viewed 19 May 2019, https://www.news-medical.net/news/20181101/Retinal-sheet-transplants-restore-vision-in-blind-rats.aspx.

Comments

The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News-Medical.Net.
Post a new comment
Post
You might also like... ×
Simplifying Gene Expression Analysis in Neuroscience Research