Nowadays, electron beam radiotherapy is conducted using metal collimators for the formation of radiation field around a tumor and protection of healthy organs and tissues.
However, the development of such a metal collimator is a time- and energy-consuming process, requiring special facilities and equipment. In most cases, it is beyond capabilities of an average hospital. The research team seeks to replace metal collimators with plastic analogs made by 3D printer.
In the modern world, 3D printing is widely used in various fields, including medicine. However, the development of a plastic collimator requires a detailed study, which results are important for medicine. For instance, we should determine its thickness and printing parameters, and optimal plastic for production."
Irina Miloichikova, an assistant at the TPU Division for Nuclear-Fuel Cycle
The research team includes Associate Prof. Sergei Stuchebrov, the Research School of High-Energy Physics, assistant Irina Miloichikova, the Division for Nuclear-Fuel Cycle, engineer-researcher Angelina Bulavskaya, the Research School of High-Energy Physics, Associate Prof. Yury Cherepennikov, the Division for Nuclear-Fuel Cycle. The team collaborates with medical physicists in Moscow and Hamburg (Germany).
The researchers used a numerical model to study HIPS- and ABS-plastic capability to completely absorb an electron beam. Then, they used this plastic to manufacture the first products through the method of layer-by-layer deposition.
One of the important points of the study was to choose the required thickness of the printed collimator.
"Metal collimators should be 1.6 cm thick to absorb the beam but, unlike metal, plastic does not have the same density and a number of other characteristics. We conducted a number of calculations and experiments to determine the thickness of a plastic product. For instance, we used special dosimeters, placed inside the plastic, to measure the depth distribution of the electron beam,"
-- Associate Prof. Sergei Stuchebrov, Research School of High-Energy Physics, says.
The first experimental models of plastic collimators were printed at Tomsk Polytechnic University, while their testing and experiments were conducted at the Moscow City Oncology Hospital No. 62 and the University Hospital Hamburg-Eppendorf (Germany).
The results showed the viability of the new methodology. So far, the team has completed documents for patenting the discovery.
Miloichikovaa, I. et al. (2019) The Feasibility of clinical electron beam formation using polymer materials produced by fused deposition modeling. Physica Medica. doi.org/10.1016/j.ejmp.2019.07.014.