Study: Most men choosing surgery for prostate cancer do not regret their decisions

Men with localized prostate cancer are faced with deciding among a range of options for treatment - including a choice between robot-assisted versus conventional prostatectomy. A new follow-up study in The Journal of Urology® finds that most patients choosing surgery for prostate cancer don't regret their decisions. The Journal of Urology®, Official Journal of the American Urological Association (AUA), is published in the Lippincott portfolio by Wolters Kluwer.

Patients who play a more active role in making decisions about prostate cancer surgery are less likely to experience "decision regret" about their choices, according to the new research by Johannes Huber, MD, PhD, of Technische Universität Dresden, Germany, and colleagues. The study also finds no difference in decision regret in men opting for open versus robot-assisted surgery.

Study looks at decision regret after prostate cancer surgery

The study included data from a large-scale German healthcare research project, called HAROW, that analyzed outcomes for men choosing different treatments for localized prostate cancer - meaning that the cancer hasn't spread beyond the prostate gland.

The name HAROW refers to the major treatment options for patients with this diagnosis - namely hormone therapy, active surveillance, radiation, operation (surgery), or watchful waiting."

Dr. Lothar Weissbach, study co-author, founder of the HAROW project

In recent years, robot-assisted prostatectomy has become an increasingly popular alternative to conventional open surgery. While the robot-assisted procedure may enable faster recovery, studies have shown "no definite advantage" in terms of prostate cancer outcomes.

Few studies have looked at decision regret by men choosing among prostate cancer treatments. "Decision related regret is a negative emotion associated with thinking about a past choice and comparing the status quo with a hypothetical situation which might have taken place with having chosen a different treatment alternative," Dr. Huber and coauthors explain.

The authors analyzed decision regret in 936 men who underwent prostate cancer surgery, of whom 532 underwent open prostate surgery and 404 underwent robot-assisted surgery. At follow-up of about six years, patients rated their "distress or remorse" about their treatment choice using a 0 to 100 Decision Regret Scale (with 100 being the highest level of regret).

Men who underwent robot-assisted surgery showed a more "self-determined role" in treatment decision-making. They were more likely to use the internet to research their treatment options and were more active in selecting the hospital where the procedure would be performed. They also chose hospitals that performed a higher volume of prostate cancer surgeries, where robot-assisted surgery was more likely to be available. "Actively involved patients may choose another hospital if there is a strong desire for robotic surgery," the researchers write.

Overall, rates of decision regret about prostate cancer surgery were low: average score on the Decision Regret Scale was just 14 of 100. Decision regret scores were similar for men undergoing robot-assisted versus open surgery, with scores of 12 and 15, respectively.

Not surprisingly, patients with better treatment outcomes - which included no cancer recurrence, good erectile function and no incontinence - had fewer regrets. Men who played a more active role in treatment decision-making were about twice as likely to have a low decision regret score (less than 15). Shorter follow-up times were also associated with lower decision regret.

Decision regret could have a lasting impact on patient satisfaction with choices for prostate cancer treatment. The new results suggest generally low levels of decision regret several years after prostate cancer surgery, regardless of the choice of surgical approaches.

While good outcomes are obviously important, being more actively involved in treatment decision-making may also lead to fewer regrets. In a discussion accompanying their paper, Dr. Huber and coauthors write, "As our study shows, personal responsibility for one's own decisions has a significant influence on decision regret."

Journal reference:

Baunacke, M., et al. (2020) Decision Regret after Radical Prostatectomy does Not Depend on Surgical Approach: 6-Year Followup of a Large German Cohort Undergoing Routine Care. The Journal of Urology.


  1. Gogs Gagnon Gogs Gagnon United States says:

    Even though I’m recovering well from prostate cancer surgery, and I’m currently 33-months in NED, if there were one thing I could do differently, that would be to join a support group as soon as I was diagnosed. Even before doing research and especially before making a decision. I didn’t realize at the time that I was in shock from just hearing the word “cancer,” and that’s not a good time to make a treatment decision. Even though my results have been very positive, they could have been very negative. In that case, I would have regretted surgery and kicked myself for not doing my homework. I encourage all men to give themselves enough time to recover from the initial shock of diagnosis and to fully consider all of the available treatment options for their particular case before making a decision.

The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
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