Lower incidence of COVID-19 in high-altitude residents is intriguing, but requires more research

Despite recent reports of lower COVID-19 incidence among high-altitude populations, current data is insufficient to conclude that high altitude is protective against the SARS-CoV-2 virus, as reported in the peer-reviewed journal High Altitude Medicine & Biology.

"The reported lower incidence of COVID-19 among high-altitude residents is quite intriguing, but epidemiological observations presented so far from high-altitude regions are preliminary," state Matiram Pun, MBBS, MSc, University of Calgary, Erik Swenson, MD, University of Washington and Editor-in-Chief of High Altitude Medicine & Biology, and coauthors

The authors also conclude that there is currently little supporting evidence for any protective benefit of genetic or nongenomic adaptation to high-altitude hypoxia.

We should avoid reaching the conclusion that any community has an innate protection from COVID-19 in the absence of robust evidence."

Researchers