1. Tony Edwards Tony Edwards United States says:

    Can someone summarize this study in plain layman's english?

    • Matt K Matt K United States says:

      The vaccine causes the test subjects in this research to have a lower response rate to fungal infections.

      The vaccine does produce a strong response to COVID-19 but can also potentially cause a lowered immune response to COVID-19.

      The vaccine effects your innate immune response and could impact your immune systems response to other vaccines (ie a severe response or lowered response)

      Most importantly it lowers your bodies ability to fight fungal infections and possibly other bacterial infections.

      Google “India fungal eye infections” I’m curious if those people were vaccinated...

      • Jason Adamcewicz Jason Adamcewicz Canada says:

        My understanding of the article is that the vaccine produces stronger/enhanced immune response to fungi, particularly candida albicans. Regarding other viruses, bacteria and fungi, it states that inflammatory cytokine production was "altered." The word "reduced" was used but it was to describe anti-inflammatory response to fungi, ie. increased inflammatory response which is another way of saying stronger immune response.

        I believe Indians with those fungal infections were naturally infected, not vaccinated, but the connection to what this article suggests has me concerned, as vaccination is meant to mimic infection in some ways. As someone who's suffered with chronic sinusitis of unknown cause (never been swabbed for fungal or bacterial cultures) for a long time, and having just received first Moderna dose, I am quite concerned.

        • Rick Boden Rick Boden Canada says:

          I'm responding to your post because I also have chronic sinusitis and suffered badly this winter to the extent it affected my sleep.  Nothing scientific about this but shortly after receiving the Pfizer shot, the symptoms almost completely disappeared.  Could be the changing season, who knows.

        • Guy Agin Guy Agin Canada says:

          You misunderstood the text. "In addition, the production of the anti-inflammatory cytokine interleukin-1Ra was reduced in response to Toll-like receptor 4 and C. albicans. This also suggests a shift towards increased inflammatory responses to fungi following vaccination, say the researchers."

      • Robin Birck Robin Birck United States says:

        I agree I’m very interested in the increased prevalence of “black fungus” infections in covid patients in India and how it relates. But isn’t this study saying there’s an increased response to fungus? “In contrast, responses to the fungal pathogen Candida albicans were higher after vaccination.”

      • Jason A. Jason A. Canada says:

        My understanding of the article is that the vaccine produces stronger/enhanced immune response to fungi, particularly candida albicans. Regarding other viruses, bacteria and fungi, it states that inflammatory cytokine production was "altered." The word "reduced" was used but it was to describe anti-inflammatory response to fungi, ie. increased inflammatory response which is another way of saying stronger immune response.

        I believe Indians with those fungal infections were naturally infected, not vaccinated, but the connection to what this article suggests has me concerned, as vaccination is meant to mimic infection in some ways. As someone who's suffered with chronic sinusitis of unknown cause (never been swabbed for fungal or bacterial cultures) for a long time, and having just received first Moderna dose, I am quite concerned.

        • Rolf Stolt-Bechtold Rolf Stolt-Bechtold Germany says:

          Reduced Cytokines but increased inflammatory reaction?
          Sounds like a better effectivity against funghi in the vaxxed since
          Inflammation is a necessary part of immune action and especially in defense against fungi it is absolut crucial!
          (The reason, why fungal infection is a  frequent steroid adverese event! Steroids suppress inflamation, and are the main weapon against the covid pneumonia! So it has been presumed reason of black fungi growth in Covid-Patients!)
          And btw black fungus outbreak has been recognized in the 2. Wave in India, long before the vaccines were available!

          www.scientificamerican.com/.../

The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
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