Sponsored Content by SciYReviewed by Louis CastelFeb 25 2026
The Pistoia Alliance’s Methods Database Project is addressing a longstanding challenge in analytical science by creating a standardized, vendor-independent format for the digital exchange of High-Performance Liquid Chromatography–Ultraviolet (HPLC-UV) methods.
Built on the Allotrope Framework and the Pistoia Alliance Data Platform, the project enables machine-readable, semantically consistent method transfer between different Chromatography Data Systems (CDS), fully aligned with FAIR (Findable, Accessible, Interoperable, and Reusable) data principles.
A pilot implementation with Merck Sharp & Dohme LLC and GSK was able to demonstrate the successful two-way exchange of standardized HPLC instructions across instruments and sites. This validated the technical feasibility of digital method sharing and set the stage for wider industry adoption.
This collaborative, pre-competitive effort delivers multiple tangible advantages:
- Reduced expenses associated with managing the method lifecycle
- Removal of manual transcription, thereby minimizing human error
- Flexibility to work with preferred laboratory tools
- Improved access to approaches and results for quality assurance and regulatory review
- Enhanced data integrity and compatibility with sophisticated data evaluation methods
- Increased reproducibility of analytical approaches
- Practical adoption of FAIR principles across the industry
About SciY
SciY is a software brand that provides a broad spectrum of scientific software solutions across the entire life sciences spectrum. SciY is a concept developed by Bruker BioSpin which emerged from collaborative efforts with various brand-neutral software partners, including Mestrelab, Arxspan, Optimal Industrial Technologies, Optimal Industrial Automation, and ZONTAL.
Fueled by a shared progressive entrepreneurial vision and the necessity to recognize the benefits and added value of a unified market presence and a diversified brand portfolio, these partners united their individual ventures under one collective brand - SciY, housed within the newly established Integrated Data Solutions Division of the Bruker BioSpin Group.
SciY consolidates all current vendor agnostic software platform and solution brands, and will encompass future innovations born from this collaborative synergy. A key motivation for SciY is to forge new and innovative, modular software solution platforms, meticulously tailored to meet the specific needs of their target markets and applications.
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