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New antibody therapy offers hope for fragile patients with Fanconi anemia

An antibody treatment developed at Stanford Medicine successfully prepared patients for stem cell transplants without toxic busulfan chemotherapy or radiation, a phase 1 clinical trial has shown.

22 Jul 2025

Microbial signals rewire immunity in esophageal squamous cell carcinoma

Esophageal squamous cell carcinoma (ESCC) is a deadly cancer with particularly high prevalence in East Asia.

21 Jul 2025

Lipoxygenase emerges as a promising antiviral agent against severe fever with thrombocytopenia syndrome

Severe fever with thrombocytopenia syndrome (SFTS) was reported in Asia, with a fatality rate that can reach as high as 50%.

18 Jul 2025

Developing AI-driven stem cell therapies to fight ovarian aging

Ovarian aging, characterized by diminishing egg reserves and quality, affects millions of women worldwide, often leading to infertility.

18 Jul 2025

Research unravels the immune secrets of a cured pediatric rhabdoid tumor

Although relatively rare, many childhood cancers remain life-threatening and lack effective personalized treatments. Rhabdoid tumors are among these fatal cancers and can develop in various tissues and organs.

16 Jul 2025

OCT imaging sheds light on embryo transport mechanism in the oviduct

In a new mouse study, researchers have used optical coherence tomography (OCT) to uncover new insights into how the fallopian tube transports preimplantation embryos toward the uterus for pregnancy.

15 Jul 2025

Light-activated drug discovery identifies broad-spectrum antivirals

UC Santa Barbara researchers and collaborators from campus biotech spinoff Integrated Biosciences, as well as Harvard, MIT and genomics company Illumina Ventures are using optogenetics - the use of light to probe the functions of living tissue - to find compounds to help our bodies more effectively help themselves in times of physiological stress.

15 Jul 2025

Biological age of the brain emerges as a powerful predictor of longevity

The candles on your birthday cake don't tell the whole story. As anyone who ever attended a high-school reunion can tell you, some people age faster than others.

10 Jul 2025

Australian scientists use AI to create protein that kills superbugs

In the last year, there has been a surge in proteins developed by AI that will eventually be used in the treatment of everything from snakebites to cancer. What would normally take decades for a scientist to create – a custom-made protein for a particular disease – can now be done in seconds.

9 Jul 2025

Study uncovers the molecular evolutionary strategies of the OxPhos system

Mitochondria are the body's "energy factories," and their proper function is essential for life. Inside mitochondria, a set of complexes called the oxidative phosphorylation (OxPhos) system acts like a biochemical assembly line, transforming oxygen and nutrients into usable energy.

4 Jul 2025

Targeting a key enzyme could reverse early Parkinson's effects

Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson's disease that's caused by a single genetic mutation, according to a new Stanford Medicine-led study conducted in mice.

2 Jul 2025

Macrophage-derived lipocalin 2 drives severe pneumonia in SARS-CoV-2 infection

Since the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), understanding the mechanisms underlying severe pneumonia has remained a major research challenge.

1 Jul 2025

New yeast model sheds light on proteasome and mitochondrial interaction

A study by the Center for Redox Processes in Biomedicine (Redoxoma) led by Marilene Demasi from the Butantan Institute (São Paulo, Brazil) presents a valuable new experimental model for investigating the interaction between the proteasome and mitochondrial function.

30 Jun 2025