Genetic Information News and Research

RSS

Two studies show potential for newborn genetic screening

Two studies published today in the American Journal of Human Genetics show the potential for genomic screening in newborns to address high rates of infant hospitalization and mortality in the United States.

9 Dec 2024

Researchers develop diabetes prediction system using clinical and genetic data

A research team led by professor Nan-Hee Kim from Korea University's College of Medicine (Nan-Hee Kim and So-Young Park of Department of Endocrinology and Metabolism; Min-Hee Kim and Jae-Young Kim of Health Science Research Center) recently developed a diabetes prediction system using clinical and genetic data. The system was registered for the domestic patent.

5 Dec 2024

New study sheds light on the molecular basis of gene expression

An international research collaboration has shed new light on the molecular basis of gene expression, the fundamental biological process that underpins how all organisms use their genetic information.

2 Dec 2024

Unveiling INST10's role in neural development and cell identity

The Wistar Institute's Alessandro Gardini, Ph.D., and lab have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular "bridge" complex demonstrate a new level of detail in the understanding of early neural development - which is fundamental for the further understanding of neurodevelopmental syndromes.

27 Nov 2024

Genetic factors drive early onset and complications of type 2 diabetes in British Asians

A genetic predisposition to having lower insulin production and less healthy fat distribution are major causes of early-onset type 2 diabetes in British Asian people.

26 Nov 2024

Study shows cancers are uniformly growing masses

Researchers at the University of Cologne and the Centre for Genomic Regulation (CRG) in Barcelona have discovered that cancer grows uniformly throughout its mass, rather than at the outer edges.

26 Nov 2024

Gene variant linked to early miscarriages identified

In what could be a major advance in understanding the genetic causes underlying human infertility, scientists led by researchers from Rutgers University-New Brunswick have identified a gene variant directly tied to early miscarriages in women.

22 Nov 2024

Study sheds light on how cells repair damaged DNA

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells.

22 Nov 2024

Mapping human biology: Human Cell Atlas leads a new era in precision medicine

The Human Cell Atlas project maps human cells to understand biology, address global health disparities, and advance personalized medicine through ethical and inclusive research practices.

21 Nov 2024

Study identifies DNA collisions driving genetic changes in cancer

Cancer researchers at the University of Chicago and the University of California, San Francisco (UCSF) have discovered that mutations in certain genes can lead to the accumulation of DNA errors, resulting in a specific type of genetic change known as large tandem duplications (TDs) that can arise from the collision of two critical cellular processes: transcription and DNA replication.

20 Nov 2024

Evo model set to transform synthetic biology and disease diagnosis

A new study presents "Evo" – a machine learning model capable of decoding and designing DNA, RNA, and protein sequences, from molecular to genome scale, with unparalleled accuracy. Evo's ability to predict, generate, and engineer entire genomic sequences could change the way synthetic biology is done.

15 Nov 2024

Researchers use cerebrospinal fluid to unlock pathways in Alzheimer's disease

A multitude of genes have been linked to the development of Alzheimer's disease. Specifically how those genes might influence the progression of neurodegeneration remains something of a black box though, in part because of the challenges of examining in molecular detail the brain of a living patient.

14 Nov 2024

StitchR technology delivers large genes for muscular dystrophy treatment

Gene therapy can effectively treat various diseases, but for some debilitating conditions like muscular dystrophies there is a big problem: size.

14 Nov 2024

Study links heart shape to genetic risk of cardiovascular diseases

A new multi-national study has revealed that the shape of the heart is influenced in part by genetics and may help predict the risk of cardiovascular diseases.

14 Nov 2024

Study shows cannabis as a genotoxic substance with cancer risks

Cannabis use causes cellular damage that increases the risk of highly cancerous tumors, according to a new paper published in the scientific journal Addiction Biology.

14 Nov 2024

Metabolic enzymes take on unexpected roles in cell division and DNA repair

Researchers at the Centre for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within the nucleus, orchestrating critical functions like cell division and DNA repair.

12 Nov 2024

CRISPR technology reveals essential noncoding RNAs in the human genome

Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins.

7 Nov 2024

CHiTA assay identifies functional twister ribozymes

The "RNA world" hypothesis proposes that the earliest life on Earth may have been based on RNA - a single-stranded molecule similar in many ways to DNA - like some modern viruses. This is because, like DNA, RNA can carry genetic information, but, like a protein, it can also act as an enzyme, initiating or accelerating reactions.

5 Nov 2024

Machine learning identifies key genes linking rheumatoid arthritis and osteoporosis

Rheumatoid arthritis is a common disease affecting an estimated 17 million people worldwide. The disease is caused by immune cells attacking the joints and can result in pain, swelling, and damage to the cartilage and bone.

5 Nov 2024