Genomics News and Research

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Genomics is the study of the complete genetic material, including genes and their functions, of an organism.

Dangerous water bead ingestions increase among young children

A new study reveals that ingestions of water beads by young children have surged in recent years. Researchers at the Center for Injury Research and Policy of the Abigail Wexner Research Institute at Nationwide Children's Hospital and the Central Ohio Poison Center analyzed calls to U.S. poison centers and found an alarming 6,532% increase in the rate of reported water bead ingestions among children younger than 6 years from 2019 to 2023, followed by a 24% decrease from 2023 to 2024.

30 Apr 2026

Single-cell sequencing reveals why some CAR-T therapies succeed while others fail

Single-cell RNA sequencing is giving researchers a clearer view of why some CAR-T cells persist, expand, kill tumors effectively, or become exhausted. The review synthesizes 44 clinical scRNA-seq studies involving 500 patients and highlights how exhaustion, memory, cytotoxicity, clonal diversity, and metabolism may shape CAR-T responses.

30 Apr 2026

Bio-Rad launches PTC Harmony 96 and PTC Harmony Deepwell Thermal Cyclers

Bio-Rad Laboratories, Inc., a global leader in life science research and clinical diagnostics products, today announced the launch of the PTC Harmony Thermal Cycler line, designed to offer broader access to optimized workflows for PCR applications such as sequencing, cloning, and genotyping.

From Bio-Rad Laboratories 29 Apr 2026

NIH awards five year grant for cardiovascular epidemiology training

Boston University Chobanian & Avedisian School of Medicine researchers Vanessa Xanthakis, PhD, FAHA, associate professor of medicine and director of research training, and Mathew Nayor, MD, MPH, associate professor of medicine, have been awarded a five-year, T32 grant from the National Institutes of Health's National Heart, Lung and Blood Institute

27 Apr 2026

Engineered cells boost production of gene editing delivery vehicles

Gene editing has emerged as a powerful approach for targeting the genetic causes of disease, but getting the editing machinery into the right cells efficiently, safely, and at the scale needed for therapies remains one of the biggest set of challenges in the field.

25 Apr 2026

Molecular map reveals how Down syndrome alters brain development

Scientists at UCLA have created one of the first cellular-resolution molecular maps detailing how Down syndrome alters human brain development before birth - a resource that resolves longstanding contradictions in the field and could lay the groundwork for future therapeutic strategies.

25 Apr 2026

Lower grip strength in early pregnancy linked to risk of hypertensive disorders of pregnancy

Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal mortality worldwide. In addition, HDP can lead to fetal growth restriction, preterm birth, and various long-term adverse health outcomes.

24 Apr 2026

Cell squeezing technology offers new breast cancer risk assessment

Researchers at City of Hope, a cancer research and treatment organization, and the University of California, Berkeley, have created a novel microfluidic platform that can assess women's breast cancer risk at the cellular level.

23 Apr 2026

Researchers receive NIH grant to accelerate Alzheimer's drug discovery efforts

Dr. Damian Young, investigator at Texas Children's Duncan Neurological Research Institute (Duncan NRI) and director of the Center for Drug Discovery at Baylor College of Medicine, along with collaborators has been awarded a $6.7 million grant from the National Institute on Aging (NIA), part of the National Institutes of Health (NIH), to develop new approaches to rapidly identify potential treatments for Alzheimer's disease and related dementias with the goal of accelerating the discovery of new therapies.

23 Apr 2026

Study maps the evolution of myeloid leukemia in children with Down syndrome

It may be possible to identify which pre-cancerous cells will develop into a rare type of blood cancer, due to new research showing that a single genetic change drives myeloid leukemia in children with Down syndrome.

23 Apr 2026

Cancer-linked mutations in the brain cells may drive Alzheimer’s disease

As the body ages, cells naturally accumulate dozens of genetic mutations each year. New research from Boston Children's Hospital, published in Cell, finds that the brain's resident immune cells, microglia, amass mutations in specific cancer-driving genes yet they don't manifest as cancer.

21 Apr 2026

Stem cell model recreates early human embryo with yolk sac

For the first time, a stem cell model has produced a structure resembling an early human embryo with a yolk-sac-like structure, from a single starting stem cell population and without direct genetic manipulation.

21 Apr 2026

Early genomic testing prevents years of inconclusive visits for pediatric patients

For many families, eight years of uncertainty meant repeated specialist visits, inconclusive genetic tests and the growing fear that a clear answer might never come. For nearly half of the children enrolled in the Telethon Undiagnosed Disease Program (TUDP), that wait is now over.

21 Apr 2026

Microbial "signatures" within the oral cavity and gut may aid in gastric cancer detection

A recent study published in Cell Reports Medicine has identified distinct microbial "signatures" within the oral cavity and gut that serve as robust biomarkers for the early detection of gastric cancer (GC).

20 Apr 2026

Single CAR T infusion shows strong response in smoldering multiple myeloma patients

A single infusion of ciltacabtagene autoleucel (Carvykti) led to a 100% minimal residual disease (MRD)-negativity rate in patients with high-risk smoldering multiple myeloma, according to results from CAR-PRISM, a phase II clinical trial, presented at the American Association for Cancer Research (AACR) Annual Meeting 2026, held April 17-22.

20 Apr 2026

Antiretroviral therapy reduces biological aging in people living with HIV

A major study presented today at ESCMID Global 2026 has found that antiretroviral therapy (ART) reduces accelerated biological ageing in people with HIV (PWH) by nearly four years, a finding that could transform how clinicians monitor HIV treatment and long-term health outcomes.

20 Apr 2026

Global proteomics data sharing grows fast as ProteomeXchange scales up

ProteomeXchange’s 2026 update shows that global proteomics data sharing continues to accelerate, with more than 64,000 datasets submitted and nearly half added in just the last three years. The paper also highlights how standards, reuse tools, and AI-ready resources are helping make mass spectrometry proteomics data more findable, accessible, and reusable.

20 Apr 2026

Proteomics and AI bring earlier risk prediction into sharper focus

This review examines how high-throughput proteomics is expanding precision medicine by improving biomarker discovery, disease prediction, and drug development. It also shows how AI is helping researchers interpret complex proteomic data while highlighting major barriers such as standardization, validation, and clinical translation.

19 Apr 2026

Why clinical proteomics faces a mass spectrometry vs. high-throughput profiling dilemma

This Clinical Chemistry and Laboratory Medicine review examines a central challenge in precision medicine: whether medical laboratories should prioritize metrologically sound, proteoform-resolving protein quantification by mass spectrometry or adopt scalable, affinity-based proteome profiling platforms built for high-throughput discovery and machine learning. It concludes that while emerging proteomics technologies expand diagnostic possibilities, careful validation, standardization, and quality assurance will be essential, with a hybrid path likely offering the most practical way forward.

19 Apr 2026