Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Fitness in midlife extends health span and overall life expectancy

How fit you are in midlife may help determine not just how long you live, but how many of those years are spent in good health, according to a new study published today in the JACC, the flagship journal of the American College of Cardiology.

22 Apr 2026

New algorithms help surgeons make high-stakes transplant decisions in minutes

A new generation of artificial intelligence (AI) tools could help save more patients who need heart transplants by making better use of donor hearts that are currently discarded, according to research presented today by Brian Wayda, MD, at International Society for Heart and Lung Transplantation (ISHLT) 46th Annual Meeting and Scientific Sessions.

22 Apr 2026

Advanced cardiac CT detects hidden heart damage and future risk

Kumamoto University researchers discover that combining two advanced heart imaging techniques can predict life-threatening cardiovascular events with high accuracy.

21 Apr 2026

Cognitive decline may signal heart trouble years before a cardiovascular event

In a large ASPREE and ASPREE-XT nested case-control study of older adults without prior cardiovascular disease, people who later experienced a CVD event showed faster cognitive decline beginning roughly 3 to 8 years before the event. Processing speed declined earliest, suggesting that subtle cognitive changes may emerge well before overt cardiovascular disease.

21 Apr 2026

Proteomics and AI bring earlier risk prediction into sharper focus

This review examines how high-throughput proteomics is expanding precision medicine by improving biomarker discovery, disease prediction, and drug development. It also shows how AI is helping researchers interpret complex proteomic data while highlighting major barriers such as standardization, validation, and clinical translation.

19 Apr 2026

Obesity, GLP-1s, and metabolic care

An interview with Professor Thomas Forst, Chief Medical Officer, hVIVO

From hVIVO 17 Apr 2026

Researchers debunk the existence of the childhood "adiposity rebound" phenomenon

In new research to be presented at this year's European Congress on Obesity in Istanbul, Turkey (12-15 May) and published in The Journal of Nutrition, a 42-year old theory as to why children's body mass index (BMI) decreases post-infancy before then rising continuously from age six years –'the adiposity rebound' is refuted using new analyses – rather than decreasing body fat, the real reason is proposed as increasing muscle mass.

17 Apr 2026

Left bundle branch area pacing improves cardiac resynchronization outcomes

Left bundle branch area pacing was found to be an effective and practical strategy for cardiac resynchronization, according to a Late-Breaking Science presentation at EHRA 2026, the annual congress of the European Heart Rhythm Association (EHRA), a branch of the European Society of Cardiology (ESC).

15 Apr 2026

Loneliness is linked to higher risk of degenerative heart valve disease

Adults who reported feeling lonely had a higher risk of developing degenerative heart valve disease, even after accounting for traditional heart disease risk factors and genetics, according to new research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

15 Apr 2026

Bayer receives MHRA approval for Kerendia® (finerenone) in adults with heart failure with LVEF ≥ 40 %

The Medicines and Healthcare products Regulatory Agency (MHRA) has granted approval for Kerendia® (finerenone), a non-steroidal, selective mineralocorticoid receptor antagonist (nsMRA), for the treatment of symptomatic chronic heart failure (HF) with left ventricular ejection fraction (LVEF) ≥ 40 %, in adults in the UK.

From Bayer PLC 13 Apr 2026

Screening-detected atrial fibrillation linked to threefold heart failure risk

Heart failure is common in people who have atrial fibrillation detected during screening, according to a presentation today at EHRA 2026 the annual congress of the European Heart Rhythm Association (EHRA), a branch of the European Society of Cardiology (ESC).

13 Apr 2026

Combined training improves fitness outcomes in heart failure patients

Heart failure affects more than 64 million people worldwide (1%–3% in the general adult population) and its prevalence is projected to increase.

10 Apr 2026

More steps cut chronic disease risk but cannot fully undo long sitting

Research shows higher daily step counts can mitigate risks of chronic diseases linked to prolonged sitting, emphasizing the need to reduce sedentary time.

10 Apr 2026

Treating heart failure patients with i.v. furosemide and HSS reduces inflammatory, remodeling markers

A new research paper was published in Volume 18 of Aging-US on March 26, 2026, titled "Effects of intravenous furosemide plus small-volume hypertonic saline solutions on inflammatory, remodeling markers and epigenetics signatures of patients with congestive acute decompensated heart failure (ADHF)."

7 Apr 2026

Mount Sinai launches Adams Valve Institute for advanced heart care

The Mount Sinai Health System today announced the launch of the Adams Valve Institute, a new global center dedicated to advancing comprehensive care and surgical techniques for patients with heart valve disease.

7 Apr 2026

How gut microbes may shape heart attack damage and recovery

This review argues that gut microbes and the metabolites they produce, especially SCFAs and TMAO, may shape how the heart responds to myocardial infarction through epigenetic pathways such as DNA methylation, histone modification, and non-coding RNAs. It also outlines potential intervention routes, including diet, probiotics, postbiotics, and metabolite-targeted therapies, while noting that much of the evidence remains translational and not yet clinically definitive.

6 Apr 2026

Irregular bedtimes double heart risk for those getting below 8 hours

Irregular sleep timing significantly impacts heart health, with inconsistent bedtimes linked to a higher risk of major cardiovascular events over a decade.

6 Apr 2026

NHS GM care in patients’ homes as NHS virtual wards expand

When Raymond from Salford was diagnosed with heart failure, he faced an extended hospital stay until NHS Greater Manchester’s virtual ward allowed him to continue his care safely at home. He received twice-daily home visits from the Salford Urgent Response team and had regular contact with clinicians looking after him to discuss and review his care. This meant he could recover more comfortably and quickly being at home.

3 Apr 2026

Study finds higher heart disease risk in long COVID patients

People with long COVID are at increased risk of developing cardiovascular disease, according to a new study from Karolinska Institutet published in eClinicalMedicine.

1 Apr 2026

Lack of dental care linked to higher heart and dementia risk

Being unable to afford dental care may increase a person's risk of developing cardiovascular disease or dementia, according to a new study led by researchers at Boston University School of Public Health (BUSPH).

1 Apr 2026