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Ancient animals reveal sleep’s original role in maintaining brain health

A groundbreaking new study from Bar-Ilan University shows that one of sleep's core functions originated hundreds of millions of years ago in jellyfish and sea anemones, among the earliest creatures with nervous systems.

6 Jan 2026

RNA splicing and processing genes emerge as central drivers of aging across tissues

A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled "A combination of differential expression and network connectivity analyses identifies a common set of RNA splicing and processing genes altered with age across human tissues."

5 Jan 2026

Epigenetic clocks accurately predict age from human skeletal muscle

A new research paper was published in Volume 17, Issue 11 of Aging-US on November 26, 2025, titled "Epigenetic aging signatures and age prediction in human skeletal muscle."

30 Dec 2025

Study validates OVCAR3 as a model for high-grade serous ovarian cancer

A new research paper was published in Volume 12 of Oncoscience on October 14, 2025, titled "Bridging clinical insight and laboratory model in high-grade serous ovarian carcinoma (HGSOC) using DNA sequencing-based profiling of TP53."

23 Dec 2025

AI analysis maps a century of global aging research

A new research paper was published in Volume 17, Issue 11 of Aging-US on November 25, 2025, titled "A natural language processing–driven map of the aging research landscape."

23 Dec 2025

Popular video games may offer meaningful emotional benefits for young adults

DNA twisting controls how cells respond to estrogen

Estrogens, the main female sex hormone, although they also perform some functions in men, are involved in a myriad of processes, which is why the body changes so much during menopause. This is because estrogens regulate hundreds of genes.

19 Dec 2025

Younger epigenetic age linked to increased depression in older women

A new research paper was published in Volume 17, Issue 11 of Aging-US on November 18, 2025, titled "Epigenetic age predicts depressive symptoms during the COVID-19 pandemic in the Canadian Longitudinal Study on Aging: importance of biological sex."

19 Dec 2025

Climate shocks creating new pathways for disease across Africa

Climate shocks are reshaping ecosystems, creating new pathways for disease across Africa, writes Albert Ansah.

15 Dec 2025

Glycation stress drives aortic stiffening through oxidative stress and senescence

A new research paper was published in Volume 17, Issue 11 of Aging-US on November 14, 2025, titled "Methylglyoxal-induced glycation stress promotes aortic stiffening: putative mechanistic roles of oxidative stress and cellular senescence."

12 Dec 2025

Contraception and surgical sterilization associated with increased life expectancy

Blocking reproduction increases lifespan in both males and females of many different species, a new international University of Otago – Ōtākou Whakaihu Waka-led study has found.

10 Dec 2025

Billions still lack essential health services despite worldwide gains in coverage

Since 2000, most countries – across all income levels and regions – have made concurrent progress in expanding health service coverage and reducing the financial hardship associated with health costs, according to a new joint report from the World Health Organization (WHO) and the World Bank Group.

6 Dec 2025

Study reveals unequal burden of sudden cardiac death among colorectal cancer survivors

A new research paper was published in Volume 12 of Oncoscience on November 7, 2025, titled "Temporal trends and disparities in sudden cardiac death among colorectal cancer patients: A nationwide study."

4 Dec 2025

Machine learning tool identifies compounds that induce cancer cells into senescence

A new research paper featured on the cover of Volume 17, Issue 11 of Aging-US was published on October 30, 2025, titled "SAMP-Score: a morphology-based machine learning classification method for screening pro-senescence compounds in p16 positive cancer cells."

1 Dec 2025

WHO releases first-ever global guideline for prevention, diagnosis and treatment of infertility

The World Health Organization (WHO) today called on countries to make fertility care safer, fairer and more affordable for all in its first-ever global guideline for the prevention, diagnosis and treatment of infertility.

29 Nov 2025

Infection-related hospital stays linked to higher risk of developing dementia

A new research paper was published in Volume 17, Issue 10 of Aging-US on October 13, 2025, titled "Hospitalization with infections and risk of Dementia: a systematic review and meta-analysis."

25 Nov 2025

Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics-meticulously placed chemical tags that influence which genes are expressed in each cell.

22 Nov 2025

Maternal age drives embryo arrest independently of chromosomal errors

A new research paper was published in Volume 17, Issue 10 of Aging-US on October 10, 2025, titled "Developmental arrest rate of an embryo cohort correlates with advancing reproductive age, but not with the aneuploidy rate of the resulting blastocysts in good prognosis patients: a study of 25,974 embryos."

20 Nov 2025

Structured infection prevention program can save mothers’ lives in low-resource settings

A landmark multi-country clinical trial has shown that a structured, sustainable approach to infection prevention and treatment can save women's lives, cutting severe maternal infections and deaths by about one-third (32%) compared to usual care.

19 Nov 2025

Research reveals new insights into the biology of recurrent miscarriage

Researchers at the Victor Chang Cardiac Research Institute, University of Sydney, and the Royal Hospital for Women have uncovered important new insights into the biology of recurrent miscarriage - a devastating condition that affects up to one in fifty couples trying to conceive.