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New scientific clue could unlock key cellular pathway leading to neurodegenerative diseases

In Nature Neuroscience, UConn School of Medicine researchers have revealed a new scientific clue that could unlock the key cellular pathway leading to devastating neurodegenerative diseases like Alzheimer's disease, and the progressive damage to the brain's frontal and temporal lobes in frontotemporal degeneration (FTD) and the associated disease amyotrophic lateral sclerosis (ALS).

14 Mar 2025

Optimized fermentation process unlocks anti-aging potential of tapuy lees

Filipino researchers have found a way to optimize the traditional procedure for making Philippine rice wine or "tapuy" to produce a potential superfood rich in anti-aging compounds and antioxidants.

14 Mar 2025

Computational framework protects privacy in voice-based cognitive health assessments

Digital voice recordings contain valuable information that can indicate an individual's cognitive health, offering a non-invasive and efficient method for assessment.

14 Mar 2025

Study links inflammation pathways to changes in bone mineral density

In one of the first studies of its kind, a team of researchers from Keck School of Medicine of USC has found that proteins and pathways involved in inflammation are associated with changes in bone mineral density (BMD) over time.

14 Mar 2025

Mitochondria may hold key to reducing inflammaging in aging cells

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way.

14 Mar 2025

Social advantage reduces risk of age-related diseases and slows aging

People with favorable socioeconomic conditions, such as high incomes or education levels, face a reduced risk of age-related diseases and show fewer signs of biological aging than peers of the same age, finds a new study led by University College London (UCL) researchers.

14 Mar 2025

Modified tool helps assess symptoms in cognitively impaired nursing home residents

As many as half of nursing home residents are cognitively impaired and may be unable to communicate symptoms such as pain or anxiety to the staff and clinicians caring for them.

14 Mar 2025

Parkinson’s disease will affect 25 million people by 2050, study warns

Global Parkinson’s disease cases are projected to more than double to 25.2 million by 2050, driven largely by aging populations and socio-demographic factors. The sharpest increases are expected in Sub-Saharan Africa and South Asia, with men disproportionately affected.

13 Mar 2025

Firefighting chemicals leave brain cancer-linked mutations, study shows

Firefighters show higher rates of glioma-linked SBS42 mutational signatures associated with haloalkane exposure, suggesting occupational risk. The study highlights a clear link between firefighting, chemical exposure, and brain cancer mutations.

13 Mar 2025

Moving abroad for retirement may increase loneliness for older adults

Many people dream of retiring to a warmer, less expensive country. But retirees who move abroad may be at greater risk of loneliness than those who stay in their home country, according to research published by the American Psychological Association.

13 Mar 2025

RSV hospitalization rates rise with age and chronic conditions in older adults

Among older adults in Spain, hospitalization rates from respiratory syncytial virus (RSV) infection increases progressively with age and is more likely among people with other health issues and who live in nursing homes, according to a study published in Eurosurveillance.

13 Mar 2025

Finnish study reveals complex link between physical activity and longevity

Physical activity is seen as a way to extend the human lifespan, but Finnish twin studies found the benefits of physical activity for longevity may not be as straightforward as has been previously thought.

13 Mar 2025

Study reveals strong link between digital exclusion and mental health of older adults

Older adults who lack internet access are at a significantly higher risk of developing depressive symptoms, especially those with limited familial support or lower income levels, according to a new study published in Health Data Science.

12 Mar 2025

Researchers uncover 195 genetic risk factors driving women’s reproductive diseases

Scientists identified 195 genetic risk loci across 42 female reproductive health conditions, revealing shared genetic pathways and developing a polygenic risk score for intrahepatic cholestasis of pregnancy (ICP). These findings pave the way for personalized reproductive healthcare and targeted treatments based on genetic risk.

12 Mar 2025

People from families with exceptional longevity have lower risk of peripheral artery disease

A new research paper was published in Aging (Aging-US) on February 25, 2025, Volume 17, Issue 2, titled "Epidemiology and genetic determination of measures of peripheral vascular health in the Long Life Family Study."

12 Mar 2025

Dementia risk higher among adults with HIV in Malawi

Adults living with HIV in Malawi are more than twice as likely to also have dementia compared to those without HIV, according to a new study by a team of US and Malawian researchers.

12 Mar 2025

Heavy menstrual bleeding may contribute to fatigue in midlife women

Multiple menopause symptoms can make women feel fatigued. Hot flashes, sleep problems, pain, and depression are just a few.

12 Mar 2025

Sent home to heal, patients avoid wait for rehab home beds

After a patch of ice sent Marc Durocher hurtling to the ground, and doctors at UMass Memorial Medical Center repaired the broken hip that resulted, the 75-year-old electrician found himself at a crossroads.

12 Mar 2025

New mobile app aids in rehabilitating hemiparesis following stroke

Brazilian researchers have developed a cell phone application that helps rehabilitate people who have suffered a stroke.

11 Mar 2025

3D imaging sheds light on how nerves and blood vessels in the skull decline with age

As the body ages, bones undergo changes that can hinder their ability to regenerate and heal. While previous studies have concentrated on the structural shifts in bone tissue itself, the role of nerves and blood vessels—critical players in bone health—has remained relatively unexplored.

11 Mar 2025