Enzyme News and Research

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Looking at cancer drugs to help put the brakes on classic indicators of aging

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

Revolutionizing Schizophrenia Research with the Queensland Brain Institute

To commemorate World Schizophrenia Awareness Day, we spoke to three researchers from the Queensland Brain Institiute about their research, and why it is so important to raise awareness around Schizophrenia

23 May 2023

AI-based method predicts small molecule substrates of enzymes

Enzymes are the molecule factories in biological cells. However, which basic molecular building blocks they use to assemble target molecules is often unknown and difficult to measure.

22 May 2023

Genetic insights unveil promising therapeutic targets for critical COVID-19

Critical COVID-19 illness reveals genetic associations with immunomodulatory therapies, as identified in a comprehensive analysis of 24,202 cases. This study uncovers novel genome-wide significant associations, highlighting potential druggable targets for inflammatory signaling, immunometabolism, and viral replication, offering insights into therapeutic implications.

21 May 2023

A novel role for macrophage-activation signaling in orchestrating the recruitment process in response to the SARS-CoV-2 spike protein

Researchers derived peptides from the SARS-CoV-2 spike protein to assess COVID-19-associated inflammatory changes using zebrafish models.

19 May 2023

COVID's latest twist: New XBB variant gains strength through recombination, outsmarting immunity and amplifying fusogenicity

Research discusses the emergence of a highly diversified SARS-CoV-2 Omicron subvariant called XBB, which is spreading rapidly around the world. XBB emerged through the recombination of two cocirculating BA.2 lineages, BJ.1 and BM.1.1.1, during the summer of 2022.

18 May 2023

Researchers discover molecular pathway that mediates cancer-associated muscle atrophy

Nearly half of all cancer patients suffer from excessive weight loss due to the loss of adipose and skeletal muscle tissues, or cachexia.

18 May 2023

Efficient assay system aids rapid genetic diagnosis of mitochondrial diseases

The gene ECHS1 encodes for enoyl-CoA hydratase short-chain 1, a mitochondrial enzyme involved in branched-chain amino acid and fatty acid metabolism.

18 May 2023

Researchers find that SARS-CoV-2 directly infects hepatocytes that cause hyperglycemia

Researchers investigate whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused hyperglycemia.

18 May 2023

Ticks found to harbor and release prions of chronic wasting disease

Researchers determined whether ticks contain transmission-relevant amounts of chronic wasting disease.

17 May 2023

Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses

Researchers generated six human monoclonal antibodies that prevented infection.

17 May 2023

Glycosylation enzyme plays a crucial role in brain development, study shows

The MGAT5 glycosylation enzyme plays a crucial role in brain development, according to a study by University of California, Irvine researchers, a discovery that may contribute to new therapeutic purposes for neural stem cells.

16 May 2023

Grape expectations: Dietary grapes promote subtle shifts in human microbiome with potential health implications

Research investigates the potential health benefits of grape consumption by examining its impact on the human microbiome. By analyzing microbiome composition and metabolites, the study provides insights into the relationship between grapes and human health.

16 May 2023

Mast cells play a crucial role in the development of chronic myeloid leukemia

Chronic myeloid leukemia (CML) is a type of blood cancer that arises from malignant changes in blood-forming cells of the bone marrow.

16 May 2023

Molecular mechanism behind a DNA repair pathway revealed

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

16 May 2023

Can the consumption of cocoa and red berries improve cardiovascular biomarkers?

Researchers explored the benefits of consuming cocoa and red berries to improve cardiovascular biomarkers.

16 May 2023

Study sheds light on the importance of a subset of microglial cells in cognition and memory

A new study sheds light on the importance of microglia, the immune cells of the brain, in cognition and memory.

15 May 2023

SARS-CoV-2 variants show altered glycan processing

Researchers examine spike-protein trimers from SARS-CoV-2 variants to compare the N (asparagine)-glycan landscape.

15 May 2023

Deep generative models to generate hypothetical SARS-CoV-2 spike sequences

Scientists explore the use of deep generative models in producing complete instances of as-yet undiscovered SARS-CoV2 Spike protein sequences. The resulting models substantially outperform a state-of-the-art generative model for protein sequences finetuned on SARS-CoV2 data.

14 May 2023

Novel ingestible device enables non-invasive profiling of the gut microbiome, proteome, and metabolome

Researchers developed an ingestible device to collect samples from the human intestine.

12 May 2023

Enzyme News and Research

Looking at cancer drugs to help put the brakes on classic indicators of aging

Revolutionizing Schizophrenia Research with the Queensland Brain Institute

AI-based method predicts small molecule substrates of enzymes

Genetic insights unveil promising therapeutic targets for critical COVID-19

A novel role for macrophage-activation signaling in orchestrating the recruitment process in response to the SARS-CoV-2 spike protein

COVID's latest twist: New XBB variant gains strength through recombination, outsmarting immunity and amplifying fusogenicity

Researchers discover molecular pathway that mediates cancer-associated muscle atrophy

Efficient assay system aids rapid genetic diagnosis of mitochondrial diseases

Researchers find that SARS-CoV-2 directly infects hepatocytes that cause hyperglycemia

Ticks found to harbor and release prions of chronic wasting disease

Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses

Glycosylation enzyme plays a crucial role in brain development, study shows

Grape expectations: Dietary grapes promote subtle shifts in human microbiome with potential health implications

Mast cells play a crucial role in the development of chronic myeloid leukemia

Molecular mechanism behind a DNA repair pathway revealed

Can the consumption of cocoa and red berries improve cardiovascular biomarkers?

Study sheds light on the importance of a subset of microglial cells in cognition and memory

SARS-CoV-2 variants show altered glycan processing

Deep generative models to generate hypothetical SARS-CoV-2 spike sequences

Novel ingestible device enables non-invasive profiling of the gut microbiome, proteome, and metabolome

Biochemistry eBook

Latest eBooks

Editorial Focus eBook - Proteomics (2nd Edition)

Industry Focus eBook - Life Science Microscopy (2nd Edition)

BFEB: Advances in microplate-based assays and analysis

Biologics stability screening toolkit: Three practical workflows for accelerating formulation development

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy