Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

Pfizer-BioNTech COVID-19 vaccine is associated with lower viral load in breakthrough infections

Several vaccines have been rapidly developed to help control the COVID-19 pandemic, including the BNT162b2 vaccine (Pfizer/BioNTech). This severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine has been shown in both clinical trials and in the real world to be highly efficacious in preventing infection, symptoms, hospitalizations, severe disease, and death related to coronavirus disease (COVID-19).

9 Nov 2021

A review of antigen-detecting rapid diagnostic tests for COVID-19

Scientists conducted a systematic review of the use cases and performance of Ag-RDTs for detecting SARS-CoV-2.

8 Nov 2021

Highly-sensitive PCR-based method to detect SARS-CoV-2 variants

A team of UK-based scientists has recently developed an allele-specific probe polymerase chain reaction method that can accurately detect different variants/lineages of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in respiratory samples. Furthermore, the method can detect viral variants even in samples with low viral RNA or degraded viral RNA. The study is currently available on the medRxiv* preprint server.

7 Nov 2021

Scientists create a rapid diagnostic technology to detect SARS-CoV-2

Blending experts from molecular genetics, chemistry and health sciences, researchers at the University of California San Diego have created a rapid diagnostic technology that detects SARS-CoV-2, the coronavirus that causes COVID-19.

6 Nov 2021

“Catching SARS-CoV-2 in the act” – viral infection of nasal mucosa spares nerve cells

A new study discusses the entry of SARS-CoV-2 into the respiratory and olfactory mucosa of the nasal cavity.

4 Nov 2021

Highly-sensitive PCR-based method to detect SARS-CoV-2 variants

A team of scientists has recently developed an allele-specific probe polymerase chain reaction method that can accurately detect different variants/lineages of SARS-CoV-2 in respiratory samples.

4 Nov 2021

Murine hepatitis virus as a surrogate for studying SARS-CoV-2 in food processing biofilms

Researchers from Texas A&M University inoculated MHV (SARS-CoV-2 surrogate) into a meat processing environmental biofilm and developed it on stainless steel (SS), PVC, and tiles at 7°C.

4 Nov 2021

Development of SARS-CoV-2 detection platform using surface-enhanced Raman spectroscopy

Researchers have tried to develop an innovative platform for ultrasensitive and rapid detection of SARS-CoV-2 by exploiting a variation of Raman Spectroscopy.

4 Nov 2021

Cas13 shines a light on SARS-CoV-2 variants

Now, a new study published on the medRxiv* preprint server describes and benchmarks SHINEv2, a Cas13-based nucleic acid diagnostic for SARS-CoV-2 detection. SHINEv2 combines temperature sample processing and lyophilized reagents to simplify the test procedure and assay distribution immensely.

4 Nov 2021

Spike antibody durability in mRNA vaccinated individuals with or without prior SARS-CoV-2 infection

A new study examined SARS-CoV-2 spike IgG antibodies in a longitudinal cohort, comparing antibody durability in individuals who received an mRNA SARS-CoV-2 vaccine with or without prior SARS-CoV-2 infection.

3 Nov 2021

What are the risk factors for severe disease in children hospitalized for SARS-CoV-2 infection?

A new preprint describes an effort to describe the risk factors for severe COVID-19 in children.

2 Nov 2021

Curious case of SARS-CoV-2 Delta variant in a dog

In a recent study, researchers document the detection and sequencing of an AY.3 virus from a 12-year-old Collie living with a SARS-CoV-2-infected owner.

1 Nov 2021

New genetic epidemiology tool provides detailed information about viruses, coinfections

With mask wearing and social distancing on the decline and the cold and flu season upon us, researchers have developed a viral panel that enables the simultaneous testing for SARS-CoV-2 along with numerous common respiratory viruses, that tells us whether other viruses also are at play in patients hard hit by COVID.

1 Nov 2021

Do weather and climate determine where COVID-19 occurs?

A new study provides information on the associations between weather parameters and seasonal coronavirus cases.

1 Nov 2021

SARS-CoV-2 antibodies persisting for nearly a year, including to delta: NZ study

A cohort study found that antibodies to the SARS-CoV-2 spike protein and neutralizing antibodies remain relatively stable 8-11 months post-infection.

1 Nov 2021

COVID-19 antibody levels stay more durable in vaccinated people with prior SARS-CoV-2 infection

In what is believed to be one of the largest studies of its kind, Johns Hopkins Medicine researchers have shown that antibody levels against SARS-CoV-2 (the COVID-19 virus) stay more durable — that is, remain higher over an extended period of time — in people who were infected by the virus and then received protection from two doses of messenger RNA (mRNA) vaccine compared with those who only got immunized.

1 Nov 2021

Polymerase Chain Reaction News and Research

Further Reading

Pfizer-BioNTech COVID-19 vaccine is associated with lower viral load in breakthrough infections

A review of antigen-detecting rapid diagnostic tests for COVID-19

Highly-sensitive PCR-based method to detect SARS-CoV-2 variants

Scientists create a rapid diagnostic technology to detect SARS-CoV-2

“Catching SARS-CoV-2 in the act” – viral infection of nasal mucosa spares nerve cells

Highly-sensitive PCR-based method to detect SARS-CoV-2 variants

Murine hepatitis virus as a surrogate for studying SARS-CoV-2 in food processing biofilms

Development of SARS-CoV-2 detection platform using surface-enhanced Raman spectroscopy

Cas13 shines a light on SARS-CoV-2 variants

Spike antibody durability in mRNA vaccinated individuals with or without prior SARS-CoV-2 infection

What are the risk factors for severe disease in children hospitalized for SARS-CoV-2 infection?

Curious case of SARS-CoV-2 Delta variant in a dog

New genetic epidemiology tool provides detailed information about viruses, coinfections

Do weather and climate determine where COVID-19 occurs?

SARS-CoV-2 antibodies persisting for nearly a year, including to delta: NZ study

COVID-19 antibody levels stay more durable in vaccinated people with prior SARS-CoV-2 infection

Curcumin, a bioactive component of turmeric, effectively neutralizes SARS-CoV-2 in vitro

Real-life SARS-CoV-2 Delta variant secondary attack rate on naval ship

Clinical assay validation for SARS-CoV-2 sequencing using Swift Biosciences amplicon panel

COVID-19 patients' eyes and tears can be infected with SARS-CoV-2

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo