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IU study sheds new light on the development and treatment of rare form of muscular dystrophy

A study by Indiana University School of Medicine researchers sheds new light on the development and treatment of a rare form of muscular dystrophy.

5 Apr 2023

Drug used to treat liver disease may decrease SARS-CoV-2 infections and reduce COVID-19 severity

SARS-CoV-2, the virus that causes COVID-19, attaches to a cellular receptor called angiotensin-converting enzyme 2 (ACE2), and activation of the farnesoid X receptor increases ACE2 expression.

5 Apr 2023

Novel molecule may help overcome the devastating symptoms of Duchenne muscular dystrophy

In a new study published in The FASEB Journal, investigators demonstrated the potential of a molecule that may help overcome some of the devastating symptoms of Duchenne muscular dystrophy (DMD), the most common life-limiting congenital neuromuscular disorder.

5 Apr 2023

Antioxidant supplementation shows potential to improve male fertility

A new study discusses the benefits of antioxidant supplementation on male fertility.

4 Apr 2023

Pre-existing immunity shapes mucosal SARS-CoV-2-specific antibody responses

In a recent study, researchers assessed serological and mucosal immunity among three differing cohorts.

4 Apr 2023

Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

Researchers discover a small molecule drug candidate that could provide immediate protection against infection with SARS-CoV-2.

4 Apr 2023

Pediatric SARS-CoV-2 seroprevalence higher than official case reports

Researchers conduct a cross-sectional survey to estimate SARS-CoV-2 antibodies in children.

3 Apr 2023

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

Researchers reviewed the existing knowledge on the mechanisms through which DNA tumor viruses evade the antiviral immunity mediated through mis-incorporated uracil (U).

3 Apr 2023

Can the Mediterranean diet and physical exercise improve the quality of life for cancer patients?

Researchers reviewed existing literature on the benefits of adopting Mediterranean diets against inflammatory conditions and cancer.

3 Apr 2023

Study identifies ultra-broad SARS-CoV-2 neutralizing antibodies that target various spike epitopes

Researchers screened the circulating B lymphocyte repertoires of coronavirus disease 2019 convalescents and vaccines using multiplexed antigen panels.

3 Apr 2023

Study indicates interspecies transmission of SARS-CoV-2 between humans and their pets occurs regularly

Researchers assessed severe acute respiratory syndrome coronavirus 2 seroprevalence among domestic pets.

3 Apr 2023

Researchers report surprising first steps that promote resistance to commonly prescribed antibiotics

Antibiotic resistance is a global health threat. In 2019 alone, an estimated 1.3 million deaths were attributed to antibiotic resistant bacterial infections worldwide.

31 Mar 2023

What is the effect of supplementing raisins on improving cognitive performance, cardiovascular risk factors, and markers of inflammation?

Researchers devised a protocol to examine the effect of raisin supplementation on cognitive function in older adults.

31 Mar 2023

AI outperforms the leading tools in predicting enzyme function

A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood.

30 Mar 2023

Monthly prophylactic fitusiran injections effective in reducing bleeds in patients with hemophilia A or B

Monthly prophylactic injections of fitusiran are effective in reducing bleeds in patients with hemophilia A or B, according to randomized controlled trials publishing simultaneously in The Lancet and The Lancet Haematology journals.

30 Mar 2023

Study offers a novel therapeutic option to combat antibiotic-resistant pneumonia

Increases in multidrug-resistance in the bacteria Streptococcus pneumoniae have made it the fourth-leading cause of death associated with antibiotic resistance.

29 Mar 2023

SARS-CoV-2 infection disrupts the RNA modifications, study reports

Coronavirus disease (COVID-19) hijacks parts of infected cells' vital RNA machinery, thereby blocking important functions in the cells. These damaging changes in the RNA can likely be reversed, potentially leading to new drugs against COVID-19, University of Gothenburg researchers show.

29 Mar 2023

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Study outlines molecular mechanisms to aid the development of new therapies to manage obesity and associated health disorders.

29 Mar 2023

Newly designed molecule disrupts the infection mechanism of SARS-CoV-2

A team of scientists led by the Department of Energy's Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.

28 Mar 2023

COVID-19 activates endogenous retroviruses within our genome

Researchers assess the impact of SARS-CoV-2 infection on endogenous retroviruses of the LTR69 subfamily.

28 Mar 2023

Enzyme News and Research

IU study sheds new light on the development and treatment of rare form of muscular dystrophy

Drug used to treat liver disease may decrease SARS-CoV-2 infections and reduce COVID-19 severity

Novel molecule may help overcome the devastating symptoms of Duchenne muscular dystrophy

Antioxidant supplementation shows potential to improve male fertility

Pre-existing immunity shapes mucosal SARS-CoV-2-specific antibody responses

Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

Pediatric SARS-CoV-2 seroprevalence higher than official case reports

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

Can the Mediterranean diet and physical exercise improve the quality of life for cancer patients?

Study identifies ultra-broad SARS-CoV-2 neutralizing antibodies that target various spike epitopes

Study indicates interspecies transmission of SARS-CoV-2 between humans and their pets occurs regularly

Researchers report surprising first steps that promote resistance to commonly prescribed antibiotics

What is the effect of supplementing raisins on improving cognitive performance, cardiovascular risk factors, and markers of inflammation?

AI outperforms the leading tools in predicting enzyme function

Monthly prophylactic fitusiran injections effective in reducing bleeds in patients with hemophilia A or B

Study offers a novel therapeutic option to combat antibiotic-resistant pneumonia

SARS-CoV-2 infection disrupts the RNA modifications, study reports

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Newly designed molecule disrupts the infection mechanism of SARS-CoV-2

COVID-19 activates endogenous retroviruses within our genome

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Advancing degrader and proximity-based drug development

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Evaluating new approaches for rare disease genomics

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