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Ancient genomes unearth degenerate transposable elements in human DNA

The human genome, an intricate tapestry of genetic information for life, has proven to be a treasure trove of strange features. Among them are segments of DNA that can "jump around" and move within the genome, known as "transposable elements" (TEs).

30 Jan 2024

"Zombie" viral fragments trigger inflammation to cause serious COVID-19 outcomes

There are many lingering mysteries from the COVID-19 pandemic. For instance, why does SARS-CoV-2, the virus behind the disease, cause severe symptoms in some patients, while many other coronaviruses don't? And what causes strange symptoms to persist even after the infection has been cleared from a person's system?

30 Jan 2024

Improving mitochondrial metabolism could be a potential therapeutic target for Alzheimer's

Nerve cells in the brain demand an enormous amount of energy to survive and maintain their connections for communicating with other nerve cells.

30 Jan 2024

Bio-Techne’s Advanced Cell Diagnostics (ACD) sets new standard in spatial biology with protease-free RNAscope multiomics

Bio-Techne Corporation (NASDAQ: TECH) today announced that Advanced Cell Diagnostics (ACD), a Bio-Techne spatial biology brand, has set a new standard with the development of a next-generation, protease-free RNAscope spatial multiomics workflow.

From Bio-Techne 30 Jan 2024

Study sheds new light on how obesity affects fat cells' mitochondria

The number of people with obesity has nearly tripled since 1975, resulting in a worldwide epidemic. While lifestyle factors like diet and exercise play a role in the development and progression of obesity, scientists have come to understand that obesity is also associated with intrinsic metabolic abnormalities.

29 Jan 2024

How does the nasal cavity's immune system combat SARS-CoV-2?

Researchers discovered that CD4+ and CD8+ T cells play a crucial role in clearing COVID-19 infection in the nasal cavity but have limited impact on lung infections, with implications for understanding and treating the virus.

28 Jan 2024

Revolutionary CAR T-cell therapy shows promise in reversing age-related metabolic dysfunction

study evaluates senolytic CAR T-cell therapy targeting uPAR-positive cells in aged mice, showing its effectiveness in mitigating age-related metabolic dysfunction and offering a potential long-lasting treatment for aging-associated conditions.

28 Jan 2024

New study opens unprecedented opportunities for bioengineering vaccine adjuvants

A valuable molecule sourced from the soapbark tree and used as a key ingredient in vaccines, has been replicated in an alternative plant host for the first time, opening unprecedented opportunities for the vaccine industry.

26 Jan 2024

Researchers discover "protective switches" that shield the coronavirus from immune system attacks

Over 700 million people were infected and almost seven million died, making SARS-CoV-2 the most devastating pandemic of the 21st century.

25 Jan 2024

Study reveals how HIV squirms its way into the nucleus during cell invasion

Because viruses have to hijack someone else's cell to replicate, they've gotten very good at it - inventing all sorts of tricks.

25 Jan 2024

New insights into why immunotherapy works for some cancers, not others

A multi-institutional study co-authored by University of Texas at Arlington scientists uncovered a mechanism by which cancer cells prevent the immune system from activating and attacking the cancerous invaders.

24 Jan 2024

Groundbreaking technology shows immense potential for treating ischemic retinopathy

A groundbreaking technology with immense potential in treating ischemic retinopathy in premature infants and diabetic patients has been developed by Professor Byoung Heon Kang and his research team in the Department of Biological Sciences at UNIST, in collaboration with Professor Dong Ho Park's team at Kyungpook National University Hospital. Ischemic retinopathy, characterized by the breakdown of the blood-retinal barrier and abnormal blood vessel growth, often leads to vision impairment and loss.

24 Jan 2024

Turning senescent tumor cells into targets for better cancer treatment

Cancer treatments, including chemotherapy, in addition to killing a large number of tumor cells, also result in the generation of senescent tumor cells (also called "zombi cells").

24 Jan 2024

mRNA therapy revives p53 to combat ovarian tumors

Ovarian cancer is often very aggressive and responds poorly to the therapies currently available. A recent study by Goethe University Frankfurt and University Hospital Frankfurt offers hope that this could change in the medium term.

24 Jan 2024

Study identifies genetic variants that influence response to preterm birth treatment

A UC San Francisco-led study has for the first time identified genetic variants that predict whether patients will respond to treatment for preterm birth, a condition that affects one in 10 infants born in the United States.

22 Jan 2024

Using AI to break the opioid addiction cycle

When Ben Brown, research assistant professor of chemistry, thinks about the opioid epidemic, he views the problem on a molecular level.

19 Jan 2024

Ludwig scientists deconstruct the blood supply of brain metastases

A Ludwig Cancer Research study has generated a granular portrait of how the cellular and molecular components of the blood vessels that feed brain metastases of melanoma and lung and breast cancers differ from those of healthy brain tissue, illuminating how they help shape the internal environment of tumors to support cancer growth and immune evasion.

19 Jan 2024

AI scores breakthrough in anemia treatment with novel PHD inhibitor

Clinical stage generative artificial intelligence (AI)-driven biotechnology company InSilico Medicine ("InSilico"), today announced that the Journal of Medicinal Chemistry, an ACS Publications journal focusing on critical studies about molecular structure and biological activity, has published the company's discovery of a novel PHD inhibitor for the treatment of anemia.

19 Jan 2024

Insilico Medicine leverages AI to identify promising new target for breast and gynecological cancers

Insilico Medicine("Insilico"), a clinical stage generative artificial intelligence (AI)-driven drug discovery company, recently published an early research that it has identified MYT1 as a promising new therapeutic target for breast and gynecological cancer, and discovered a series of novel, potent, and highly selective inhibitors specifically targeting MYT1.

19 Jan 2024

Groundbreaking study identifies FAM3C as a key regulator of breast cancer progression

A groundbreaking study conducted by Professor Jiyoung Park and her research team in the Department of Biological Sciences at UNIST has identified FAM3C, a metabolism-regulating signaling molecule produced by cancer-associated adipocytes (CAAs), as a key regulator of breast cancer progression within the tumor microenvironment (TME).

19 Jan 2024

Molecule News and Research

Ancient genomes unearth degenerate transposable elements in human DNA

"Zombie" viral fragments trigger inflammation to cause serious COVID-19 outcomes

Improving mitochondrial metabolism could be a potential therapeutic target for Alzheimer's

Bio-Techne’s Advanced Cell Diagnostics (ACD) sets new standard in spatial biology with protease-free RNAscope multiomics

Study sheds new light on how obesity affects fat cells' mitochondria

How does the nasal cavity's immune system combat SARS-CoV-2?

Revolutionary CAR T-cell therapy shows promise in reversing age-related metabolic dysfunction

New study opens unprecedented opportunities for bioengineering vaccine adjuvants

Researchers discover "protective switches" that shield the coronavirus from immune system attacks

Study reveals how HIV squirms its way into the nucleus during cell invasion

New insights into why immunotherapy works for some cancers, not others

Groundbreaking technology shows immense potential for treating ischemic retinopathy

Turning senescent tumor cells into targets for better cancer treatment

mRNA therapy revives p53 to combat ovarian tumors

Study identifies genetic variants that influence response to preterm birth treatment

Using AI to break the opioid addiction cycle

Ludwig scientists deconstruct the blood supply of brain metastases

AI scores breakthrough in anemia treatment with novel PHD inhibitor

Insilico Medicine leverages AI to identify promising new target for breast and gynecological cancers

Groundbreaking study identifies FAM3C as a key regulator of breast cancer progression

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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