Physiology News and Research

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Human physiology is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems. Most aspects of human physiology are closely homologous to corresponding aspects of animal physiology, and animal experimentation has provided much of the foundation of physiological knowledge. Anatomy and physiology are closely related fields of study: anatomy, the study of form, and physiology, the study of function, are intrinsically tied and are studied in tandem as part of a medical curriculum.

Two proteins work in tandem to build lifelines to cancer cells, study finds

In human cancer cell and mouse studies, researchers from Johns Hopkins Medicine have found that a set of proteins work in tandem to build supply lines that deliver oxygen and nutrients to tumors, enabling them to survive and grow.

20 Sep 2021

Atherosclerosis found in more than 40% of adults in Sweden without known heart disease

More than 40% of adults ages 50 to 64 years in Sweden without known heart disease were found to have some degree of atherosclerosis, according to a new study published today in the American Heart Association's flagship journal Circulation.

20 Sep 2021

Organs-on-chips for personalized medicine and to assess drug efficacy

Organs-on-chips could be used to assess drug efficacy and support personalized medicine, write Adrian Roth and colleagues in a Perspective.

17 Sep 2021

UTSW researchers discover how vitamin A enters immune cells in the intestines

Immunologists and geneticists at UT Southwestern Medical Center have discovered how vitamin A enters immune cells in the intestines – findings that could offer insight to treat digestive diseases and perhaps help improve the efficacy of some vaccines.

16 Sep 2021

Researchers examine the persistent effects of COVID-19 on vascular function of young adults

In a first-of-its-kind study, researchers have examined the persistent effects of SARS-CoV-2 infection on the vascular function of otherwise healthy young adults. The research, published in the American Journal of Physiology-Heart and Circulatory Physiology, was chosen as an APSselect article for September.

16 Sep 2021

New review highlights several opportunities for improving ginsenoside production

Ginseng, a widely popular superfood, has long been used in traditional medicine. The health benefits of ginseng are largely attributed to compounds called ginsenosides, which are present in the roots, stems, and leaves of the plant. Ginsenosides are known to prevent inflammation, diabetes, and cancer, and can also help control blood cholesterol levels and reduce aging.

16 Sep 2021

Family's socio-economic status may influence children's composition of gut microbiome

Findings of a nationwide study led by the Translational Genomics Research Institute, an affiliate of City of Hope, suggest that a family's socio-economic status may influence children's composition of gut microbiome - the mix of microscopic organisms within the digestive tract.

14 Sep 2021

Marshall University researcher awarded $1.36 million NIH grant for kidney-related study

Sandrine V. Pierre, Ph.D., associate professor of biomedical sciences at the Marshall University Joan C. Edwards School of Medicine and interim director of the Marshall Institute for Interdisciplinary Research (MIIR), has been awarded a Research Project Grant (R01), one of the most competitive grants issued by the National Institutes of Health.

10 Sep 2021

UC San Diego receives $12.25 million NIH grant to improve epilepsy treatment

The National Institutes of Health has awarded a $12.25 million grant to the University of California San Diego to develop and enhance brain-sensing and brain-stimulating platform technologies to enable treatment of drug-resistant epilepsy.

10 Sep 2021

COVID-19 vaccine antibodies inversely related to BMI in obese men, but not women

A new study discusses the role of obesity in COVID-19 and its role in antibody-mediated immune responses to the COVID-19 vaccine.

7 Sep 2021

Understanding how pathogens evolve novel virulence activities

Understanding how pathogens evolve is a fundamental component of learning how to protect ourselves and our world from pests and diseases.

7 Sep 2021

Increase in social stress may be connected to global population decline

A University of Massachusetts Amherst environmental health scientist has developed an "overlooked hypothesis" to help explain the projected global population decline beginning in 2064: social stress.

7 Sep 2021

Researchers find potential new target for treating systemic inflammation in obesity

A study led by researchers at the University of Chicago and Indiana University has determined that a protein called elF5A is necessary for driving inflammation in macrophage cells in obesity.

7 Sep 2021

Research uses rodent models to connect the influence of feronomic signals on memory

The work, published recently in Nature Communications, used a model of rodents and managed to connect for the first time the influence of feronomic signals on memory. This will make it possible to explore the deficits of integration of spatial memories and social studies in transgenic models of Alzheimer's disease in the future.

7 Sep 2021

High fat diets break the body clock in rats leading to over-eating and obesity

When rats are fed a high fat diet, this disturbs the body clock in their brain that normally controls satiety, leading to over-eating and obesity. That's according to new research published in The Journal of Physiology.

7 Sep 2021

Scientists identify novel mechanism that links genetic defect in IBD patients to gut leakiness

A team of researchers led by a biomedical scientist at the University of California, Riverside, has identified a novel mechanism by which loss-of-function mutations in the gene PTPN2, found in many patients with inflammatory bowel disease, or IBD, affect how intestinal epithelial cells maintain a barrier.

3 Sep 2021

Should pregnant women be vaccinated against COVID-19?

A recent study examines whether COVID-19 risks in pregnant women justify the administration of COVID-19 vaccines to pregnant individuals.

2 Sep 2021

Study highlights the robustness of miRNA modulation during aging process

Aging-US published "miRNAs generated from Meg3-Mirg locus are downregulated during aging" which reported that Aging determines a multilevel functional decline and increases the risk for cardiovascular pathologies.

28 Aug 2021

Moderate-vigorous physical activity found to be the most efficient at improving fitness

In the largest study performed to date to understand the relationship between habitual physical activity and physical fitness, researchers from Boston University School of Medicine (BUSM) have found that higher amount of time spent performing exercise (moderate-vigorous physical activity) and low-moderate level activity (steps) and less time spent sedentary, translated to greater physical fitness.

28 Aug 2021

Mystery of roe deer embryonic diapause revealed

Everyone is familiar with the roe deer, either from crossword puzzles or from real-life encounters during a jog or a hike in the forest: majestic creatures with elegant big black eyes.

28 Aug 2021

Physiology News and Research

Two proteins work in tandem to build lifelines to cancer cells, study finds

Atherosclerosis found in more than 40% of adults in Sweden without known heart disease

Organs-on-chips for personalized medicine and to assess drug efficacy

UTSW researchers discover how vitamin A enters immune cells in the intestines

Researchers examine the persistent effects of COVID-19 on vascular function of young adults

New review highlights several opportunities for improving ginsenoside production

Family's socio-economic status may influence children's composition of gut microbiome

Marshall University researcher awarded $1.36 million NIH grant for kidney-related study

UC San Diego receives $12.25 million NIH grant to improve epilepsy treatment

COVID-19 vaccine antibodies inversely related to BMI in obese men, but not women

Understanding how pathogens evolve novel virulence activities

Increase in social stress may be connected to global population decline

Researchers find potential new target for treating systemic inflammation in obesity

Research uses rodent models to connect the influence of feronomic signals on memory

High fat diets break the body clock in rats leading to over-eating and obesity

Scientists identify novel mechanism that links genetic defect in IBD patients to gut leakiness

Should pregnant women be vaccinated against COVID-19?

Study highlights the robustness of miRNA modulation during aging process

Moderate-vigorous physical activity found to be the most efficient at improving fitness

Mystery of roe deer embryonic diapause revealed

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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