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New SARS-CoV-2 Omicron XBB.1.5 variant has high transmissibility and infectivity, study finds

COVID-19 has caused significant global panic after its rapid emergence more than 3 years ago. Although we now have highly effective vaccines against the SARS-CoV-2 virus, which causes COVID-19, scientists continue to study emerging SARS-CoV-2 variants in order to safeguard public health and devise global preventive strategies against emerging variants.

20 Mar 2023

CRISPR-based genome editing restores the vision of mice with retinitis pigmentosa

Researchers in China have successfully restored the vision of mice with retinitis pigmentosa, one of the major causes of blindness in humans.

17 Mar 2023

Study suggests a novel strategy to combat multidrug-resistant S. pneumoniae infections

Pneumococcal disease leads to over three million hospitalizations and hundreds of thousands of deaths annually.

17 Mar 2023

Does vitamin D play an anti-viral role against SARS-CoV-2?

Researchers screened various compounds for anti-viral properties against SARS-CoV-2.

17 Mar 2023

Research highlights the potential risk of secondary SARS-CoV-2 transmission from wild rats

In a recent study published in the journal mBio, researchers in the United States evaluated rat exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in New York City (NYC).

16 Mar 2023

Monoclonal antibody-based blocking ELISA for SARS-CoV-2 detection in animals

In a recent study posted to the bioRxiv* preprint server, researchers in the United States described a blocking enzyme-linked immunosorbent assay (ELISA) to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure in animals.

16 Mar 2023

A novel pan-sarbecovirus vaccine candidate neutralizes Omicron BQ.1.1 and XBB subvariants

Researchers provide evidence that a novel vaccine candidate robustly neutralized SARS-CoV-2 Omicron subvariants BQ.1.1 and XBB.

16 Mar 2023

Stimulus-sensitive polymeric micelles show promise for future targeted drug delivery and chemotherapy

Researchers documented the various polymeric materials that can be used to synthesize micelles, which can then be used for targeted cancer therapy by tailoring the micelles to respond to stimuli.

16 Mar 2023

PBD Biotech’s new lyophilized PCR reaction bead offers easy ambient shipping, extends global reach of active TB test

Tuberculosis testing and treatment needs to happen close to the point of infection. PBD Biotech has developed a lyophilized PCR reaction bead for its Actiphage® blood test for active TB.

16 Mar 2023

Malfunctioning of novel regulatory brain mechanism may be an early contributor of Alzheimer's disease

Researchers from Drexel University have uncovered a novel regulatory mechanism in the brain that is essential for making the right kinds of proteins that promote healthy brain function, and its malfunctioning may be an early contributor of the development of Alzheimer's disease.

15 Mar 2023

Vitamin A-rich diet may reduce risk of developing asparaginase-associated pancreatitis in ALL patients

Consuming a diet rich in vitamin A or its analogs may help prevent children and young adults with acute lymphoblastic leukemia (ALL) reduce their risk of developing painful pancreas inflammation during chemotherapy treatment.

15 Mar 2023

Point-of-care test identifies patients who may benefit from hypnosis interventions for pain treatment

Hypnosis is an effective treatment for pain for many individuals but determining which patients will benefit most can be challenging. Hypnotizability testing requires special training and in-person evaluation rarely available in the clinical setting.

15 Mar 2023

Age and sex determine the effects of microbiota on mice's metabolome

The gut handles all ingested foods for further digestion and assimilation. In addition, it harbors a wealth of microbes that produce metabolic byproducts with multiple effects on host physiology. Therefore, changes in the gut microbiome's composition can shift the gut's metabolome as well.

15 Mar 2023

An overview of COVID-19-associated neurological complications in children

Researchers review current literature to understand the association between COVID-19, neuroimaging, and neurological symptoms in children.

14 Mar 2023

Study identifies link between oral and gut microbiomes and depression

Researchers investigate the role of the oral-gut-brain axis in anxiety and depression.

14 Mar 2023

Spike-induced humoral immunity and its association with antibody-dependent cellular cytotoxicity potency

A new study aimed to analyze the qualitative and quantitative impact of S-induced humoral immunity along with its ADCC capability in individuals who received a vaccination, recovered from an infection, or both.

14 Mar 2023

Specific enzyme produced in liver cancer cells could turn a molecule into potential anticancer drug

Scientists at the National Institutes of Health and Massachusetts General Hospital in Boston have uncovered a potential new approach against liver cancer that could lead to the development of a new class of anticancer drugs.

14 Mar 2023

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

Researchers investigated whether mRNA technology-based COVID-19 vaccines promote the development of autoantibodies.

14 Mar 2023

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Researchers showed that mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) chromatin remodeling complexes represent a potential class of host-directed broad-acting SARS-CoV-2 therapeutic targets.

14 Mar 2023

Oral host responses to SARS-CoV-2 predict progression of COVID-19

In a recent study posted to the medRxiv* preprint server, researchers at the University of North Carolina and the National Institutes of Health determined the associations between oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), oral antibodies against SARS-CoV-2, and coronavirus disease 2019 (COVID-19) symptoms.

14 Mar 2023

Enzyme News and Research

New SARS-CoV-2 Omicron XBB.1.5 variant has high transmissibility and infectivity, study finds

CRISPR-based genome editing restores the vision of mice with retinitis pigmentosa

Study suggests a novel strategy to combat multidrug-resistant S. pneumoniae infections

Does vitamin D play an anti-viral role against SARS-CoV-2?

Research highlights the potential risk of secondary SARS-CoV-2 transmission from wild rats

Monoclonal antibody-based blocking ELISA for SARS-CoV-2 detection in animals

A novel pan-sarbecovirus vaccine candidate neutralizes Omicron BQ.1.1 and XBB subvariants

Stimulus-sensitive polymeric micelles show promise for future targeted drug delivery and chemotherapy

PBD Biotech’s new lyophilized PCR reaction bead offers easy ambient shipping, extends global reach of active TB test

Malfunctioning of novel regulatory brain mechanism may be an early contributor of Alzheimer's disease

Vitamin A-rich diet may reduce risk of developing asparaginase-associated pancreatitis in ALL patients

Point-of-care test identifies patients who may benefit from hypnosis interventions for pain treatment

Age and sex determine the effects of microbiota on mice's metabolome

An overview of COVID-19-associated neurological complications in children

Study identifies link between oral and gut microbiomes and depression

Spike-induced humoral immunity and its association with antibody-dependent cellular cytotoxicity potency

Specific enzyme produced in liver cancer cells could turn a molecule into potential anticancer drug

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Oral host responses to SARS-CoV-2 predict progression of COVID-19

Understanding the DNA Damage Response in Innate Immunity eBook

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