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Gene linked to lower BMI points researchers toward a new obesity target

A review in Cardiology in Review highlights GPR75, a receptor for 20-HETE, as a promising therapeutic target for obesity and metabolic syndrome. Evidence from genetic studies, cell experiments, and mouse models suggests that blocking this pathway could influence weight gain, insulin resistance, hypertension, inflammation, and vascular dysfunction.

25 Jun 2026

Common genetic difference may increase the risk of severe COVID-19 and lung fibrosis

A genetic difference carried by nearly one in three people may increase the risk of severe COVID-19 and lung fibrosis by disrupting the function of a previously unknown protein, according to a new study.

24 Jun 2026

Hidden protein linked to severe COVID-19 and lung disease risk

24 Jun 2026

New microneedle patch offers enzyme-free continuous glucose monitoring

More than 500 million people worldwide live with diabetes, making reliable continuous glucose monitoring (CGM) a critical yet unmet need.

23 Jun 2026

Scientists unlock molecular structure of key protein linked to cancer, neurological diseases

After nearly four decades of research, Mayo Clinic scientists have revealed the molecular structures of protein kinase C beta (PKCβ), a key protein linked to cancer and neurological diseases.

23 Jun 2026

Scientists uncover new molecular mechanism driving gastrointestinal stromal tumors

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive tract, with KIT mutations driving approximately 75% to 80% of cases.

23 Jun 2026

Researchers identify control switch protein that starves tuberculosis bacteria

A protein that acts as a 'control switch,' preventing Mycobacterium tuberculosis from accessing the energy sources it needs to survive, has been identified by researchers at the University of Surrey.

23 Jun 2026

New human protein atlas maps how cancer rewires the body’s tissues

Researchers created a DIA-MS atlas of 13,609 proteins across 2,856 samples from fetal, healthy adult, paired non-tumor, and tumor tissues. The resource maps tissue-specific protein patterns, cancer-associated changes, organ-specific drug-toxicity signals, and candidate therapeutic targets.

21 Jun 2026

Heart failure treatments protect heart function during cancer therapy

The cardioprotective effects of heart failure treatments in patients with cancer were demonstrated today in a presentation at ESC Cardio-Oncology 2026, the annual conference of the European Society of Cardiology's Council of Cardio-Oncology.

19 Jun 2026

Study shows jumping genes can transfer between different species

Genes are not passed on exclusively from parents to their offspring. Some are mobile and can also jump to other species, as researchers at the Max Planck Institute for Marine Microbiology in Bremen have now shown.

19 Jun 2026

Study discovers epigenetic mechanism protecting tooth progenitor cells from stress

An epigenetic "mechanostat" has been discovered that protects tooth-forming progenitor cells from mechanical stress and supports lifelong tissue renewal.

19 Jun 2026

Epigenetic drugs improve blood vessel health in obesity and diabetes

People with obesity and type 2 diabetes are at high risk of blood vessel damage. This risk depends not only on the genes a person carries, but also on how they are "read".

18 Jun 2026

Deep learning identifies novel compounds against antibiotic-resistant gonorrhea

With tens of millions of annual cases, gonorrhea is the second most frequently reported sexually transmitted infection (STI). Alone in the U.S., over 600,000 cases are reported each year.

17 Jun 2026

WashU study identifies shared target for a new diarrhea vaccine

The bacteria enterotoxigenic E. coli and Shigella together cause hundreds of millions of infections each year and are among the leading causes of diarrheal death, especially in children.

17 Jun 2026

Developing brain cells routinely repair severe DNA damage during migration

Newborn nerve cells must squeeze through crowded, narrow spaces-through dense tissue, past other cells, between fibers-to reach the areas where they form neural circuits in the brain cortex.

17 Jun 2026

Purdue develops next-generation platform to accelerate cancer drug discovery

Researchers at the Purdue Institute for Cancer Research (PICR) have developed a next-generation technology platform designed to dramatically accelerate one of the slowest and most challenging stages of cancer drug discovery: identifying promising compounds that could eventually become new therapies.

16 Jun 2026

Gut bacteria may help explain why fatigue appears before illness

A small study of healthy Japanese adults found that fatigue was associated with distinct gut microbiome, microbial gene, and fecal metabolite patterns. The findings suggest fatigue may track with altered microbial energy metabolism and oxidative stress-related functional potential, but larger longitudinal studies are needed to test causality and clinical value.

16 Jun 2026

Mutation in OTULIN gene causes rare childhood skin disease

An international team of researchers has identified a genetic cause for a rare inflammatory skin condition.

15 Jun 2026

Light-controlled molecular switch wakes lung cancer cells for treatment

Researchers from ETH Zurich have developed a molecular switch that is controlled by light. It wakes lung cancer cells up from a protective dormant state so that they are more accessible for treatment.

15 Jun 2026

Study identifies immune pathway driving long-term concussion damage

Traumatic brain injuries (TBI) - even mild concussions - may trigger a chain reaction in the brain that disrupts neuronal communication, long-term memory, and cognition, according to University of California, Riverside research investigating how the brain's immune system responds after injury.

12 Jun 2026