Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Study: A subset of patients with localized prostate cancer may benefit from immunotherapies

In recent years, cancer immunotherapy has been effective in treating patients with immunogenic, or so-called "hot" tumors with increased levels of inflammation and the presence of immune cells in and around the tumors.

24 Jun 2021

SARS-CoV-2 causes ER-stress-activated unfolded protein response leading to cell death

A new study describes the varying ways in which the virus co-opts the machinery of the host cell following infection to evade or modulate the host immune response, alter the pattern of translation of viral proteins, and the release of new viral particles.

24 Jun 2021

Black and Hispanic Americans suffer most in biggest US decline in life expectancy since WWII

Although James Toussaint has never had covid, the pandemic is taking a profound toll on his health.

24 Jun 2021

Researchers identify the origins of seven types of kidney cancer

The origins of seven types of kidney cancer, including several rare subtypes, have been identified by researchers at the Wellcome Sanger Institute, Great Ormond Street Hospital (GOSH), the Princess Máxima Center for Pediatric Oncology and Oncode Institute.

24 Jun 2021

Study finds no evidence for remdesivir's benefit in severe COVID-19 patients

A new analysis of current data indicates that remdesivir does not show efficacy in regulating the severity of the illness.

23 Jun 2021

In utero exposure to high levels of manganese, selenium may protect children from high blood pressure

Children who were exposed to higher levels of trace minerals manganese and selenium during their mothers' pregnancy had a lower risk of high blood pressure in childhood, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

23 Jun 2021

Study finds higher mortality and lower transplant rates among Black patients with cirrhosis

Black patients with cirrhosis - late-stage liver disease - are about 25% more likely to die compared to non-Hispanic white patients and four times less likely to receive a liver transplant, reports a new Northwestern Medicine study.

23 Jun 2021

Can antioxidants help manage neurological complications in COVID-19?

In a recent study published in Antioxidants, researchers evaluated the use of antioxidants as potential adjuvants for the treatment of COVID-19.

23 Jun 2021

Animal and plant-based protein-rich foods are not metabolically equivalent, finds study

Dietary protein is needed to supply essential amino acids for the synthesis of the structural and functional components of living cells. Thus, food protein quantity and quality are both essential for good health.

23 Jun 2021

Albumin supplementation improves human fertility, fights infection

A new University of California, Irvine-led study reveals albumin (Alb), among the most abundant proteins in the body, activates a proton channel (hHv1), also widespread in the body, giving sperm the ability to penetrate and fertilize an egg, and allowing white blood cells to secrete large amounts of inflammatory mediators to fight infection.

22 Jun 2021

Bruker’s molecular phenomics research tools enable new insights into ‘long COVID’ and post-acute metabolic abnormalities

A clinical research collaboration on COVID-19 pheno-conversion and subsequent pheno-reversion has discovered transient and persistent systemic changes of the molecular signatures in patient blood samples three months after the acute COVID-19 disease phase.

From Bruker BioSpin - NMR, EPR and Imaging 22 Jun 2021

Unrepaired DNA damage can increase the speed of aging, study suggests

Every day, our bodies face a bombardment of UV rays, ozone, cigarette smoke, industrial chemicals and other hazards.

21 Jun 2021

Could the European hedgehog be a sentinel for infectious agents and a harbinger of environmental pollution?

A recent review paper by Portuguese and Spanish authors, recently published in the journal Biologics, revealed the current state of knowledge regarding hedgehog health – most notably the presence of infectious agents, diseases and other threats that can affect the health of the population.

21 Jun 2021

New research uncovers substantial differences in rates of childhood cancers

New research uncovers substantial differences in rates of childhood cancers when considering single year of age rather than grouping several years together.

21 Jun 2021

New guidance provides valuable direction in the clinical use of HR-pQCT imaging

In recent years, significant progress has been made towards the use of high-resolution peripheral computed tomography (HR-pQCT) imaging in research, and new potential for applications in the clinic have emerged, particularly with the advent of second generation devices.

18 Jun 2021

Study may provide the basis to develop new therapies for urinary tract infections, kidney stones

The normal function of uromodulin, a protein that is made in the kidney and secreted into the urine, remains largely unknown. However, higher levels of uromodulin in the urine are related to lower rates of urinary tract infections and kidney stones, while higher levels of this protein in kidney cells are associated with higher rates of hypertension and chronic kidney disease.

17 Jun 2021

Reducing coronavirus-related mortality through senolytics

A study recently published in the journal Science explores the concept of senescent cells (SnC) having a hyperinflammatory response and the use of a class of small molecules called senolytics to combat this.

16 Jun 2021

Study finds low rate of SARS-CoV-2 reinfection for patients with severe illness

A review of more than 9,000 U.S. patients with severe COVID-19 infection showed less than 1% contracted the illness again, with an average reinfection time of 3.5 months after an initial positive test.

15 Jun 2021

Could urine tests predict kidney injury and mortality in COVID-19?

A team of scientists from the Columbia University, New York, has recently identified a potential biomarker to predict acute kidney injury in COVID-19 patients. By analyzing urine samples of 444 COVID-19 patients, they have revealed that the urinary level of neutrophil gelatinase-associated lipocalin (NGAL) can be used to determine the severity and duration of acute kidney and tubular injuries, as well as to predict the risk of mortality in acute COVID-19 patients.

15 Jun 2021

Study finds ‘widespread’ use of toxic chemicals in a range of cosmetics

Cosmetics from the United States have been found to contain high levels of polyuoroalkyl substances (PFAS), associated with a range of harmful conditions.

15 Jun 2021

Nephrology News and Research

Further Reading

Study: A subset of patients with localized prostate cancer may benefit from immunotherapies

SARS-CoV-2 causes ER-stress-activated unfolded protein response leading to cell death

Black and Hispanic Americans suffer most in biggest US decline in life expectancy since WWII

Researchers identify the origins of seven types of kidney cancer

Study finds no evidence for remdesivir's benefit in severe COVID-19 patients

In utero exposure to high levels of manganese, selenium may protect children from high blood pressure

Study finds higher mortality and lower transplant rates among Black patients with cirrhosis

Can antioxidants help manage neurological complications in COVID-19?

Animal and plant-based protein-rich foods are not metabolically equivalent, finds study

Albumin supplementation improves human fertility, fights infection

Bruker’s molecular phenomics research tools enable new insights into ‘long COVID’ and post-acute metabolic abnormalities

Unrepaired DNA damage can increase the speed of aging, study suggests

Could the European hedgehog be a sentinel for infectious agents and a harbinger of environmental pollution?

New research uncovers substantial differences in rates of childhood cancers

New guidance provides valuable direction in the clinical use of HR-pQCT imaging

Study may provide the basis to develop new therapies for urinary tract infections, kidney stones

Reducing coronavirus-related mortality through senolytics

Study finds low rate of SARS-CoV-2 reinfection for patients with severe illness

Could urine tests predict kidney injury and mortality in COVID-19?

Study finds ‘widespread’ use of toxic chemicals in a range of cosmetics

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