Organoids News and Research

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Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

Scientists provide metrics for organ development

Organs in the human body have complex networks of fluid-filled tubes and loops. They come in different shapes and their three-dimensional structures are differently connected to each other, depending on the organ.

21 Nov 2022

Using induced pluripotent stem cells to recreate the adrenal gland in a petri dish

Sitting atop the kidneys, the adrenal gland plays a pivotal role in maintaining a healthy body. Responding to signals from the brain, the gland secretes hormones that support critical functions like blood pressure, metabolism, and fertility.

21 Nov 2022

Brain organoids reveal how alcohol exposure impairs the development and functioning of new brain cells

Alcohol consumption during pregnancy poses significant peril to the healthy development of the unborn child. There is no known safe amount of alcohol during pregnancy.

20 Nov 2022

Researchers make first bone marrow 'organoids' to capture key features of human bone marrow

Scientists from Oxford University and the University of Birmingham have made the first bone marrow 'organoids' that capture the key features of human bone marrow.

15 Nov 2022

Researchers discover residual tumor cells responsible for colon cancer relapse

Colon cancer is the third most common cancer in the world, with about 2 million new cases each year. Most patients are diagnosed when the tumor is still located in the colon or rectum.

9 Nov 2022

Researchers use brain organoids to show how SARS-CoV-2 virus infects cortical neurons

Using human brain organoids, an international team of researchers, led by scientists at University of California San Diego School of Medicine and Sanford Consortium, has shown how the SARS-CoV-2 virus that causes COVID-19 infects cortical neurons and specifically destroys their synapses -; the connections between brain cells that allow them to communicate with each other.

3 Nov 2022

First preclinical model to study the pathobiology of appendiceal cancer

Appendiceal cancer (malignancies of the appendix, a small tissue pouch that is part of the gastrointestinal tract) is very rare, occurring in perhaps one or two people per 1 million per year.

1 Nov 2022

Researchers fabricate cerebral cortical tissues in 3D and functionally integrate them into a brain lesion in mice

Researchers fabricated cerebral cortical tissues in 3D and functionally integrated them into a brain lesion in mice.

1 Nov 2022

Researchers successfully generate fully mature hair follicles in cultures

A team of researchers from Japan studying the processes of hair follicle growth and hair pigmentation has successfully generated hair follicles in cultures.

21 Oct 2022

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

In a recent study published in the journal Nature Cell Biology, researchers demonstrated the susceptibility of salivary glands to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in vitro using an organoid culture model.

20 Oct 2022

Understanding the potential applications of stem cell research

To mark Stem Cell Awareness Day on October 12, 2022, COST is highlighting a network of researchers working to foster greater understanding about stem cell research and potential applications for millions of people suffering from incurable diseases and injury.

12 Oct 2022

New method allows for a much more detailed examination of the brain processes

Scientists have developed a research method that allows for a much more detailed examination of the brain processes involved in some neurological and mental disorders.

12 Oct 2022

Researchers take new approach to studying the development of the human brain

Researchers at ETH Zurich are growing human brain-like tissue from stem cells and are then mapping the cell types that occur in different brain regions and the genes that regulate their development.

7 Oct 2022

Study using human and animal-derived cell lines suggests human origin of SARS-CoV-2 Omicron variant

Researchers examined the replicative capacity of seven SARS-CoV-2 isolates in 17 cell lines to understand their phenotypic variations and host range.

7 Oct 2022

Improved brain organoids provide cellular and molecular insights into autism

Whatever you do, don't call them "mini-brains," say University of Utah Health scientists. Regardless, the seed-sized organoids-;which are grown in the lab from human cells-;provide insights into the brain and uncover differences that may contribute to autism in some people.

6 Oct 2022