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Scientists map genetic variants behind prostate cancer therapy failure

Recently, the research group led by Dr. Dechao Feng, Lecturer at University College London (UCL) and Distinguished Research Fellow at Zhejiang Provincial People's Hospital, published a review entitled "Intratumoral Androgens and Genetic Variants Driving Therapy Resistance in Prostate Cancer".

22 May 2026

Optimized extended PCLS culture system extends tissue viability up to two weeks

Precision-cut liver slice (PCLS) technology has long been regarded as a promising ex vivo platform because it preserves the native multicellular architecture of liver tissue.

22 May 2026

Could blocking inflammation help treat difficult-to-treat depression?

A small proof-of-concept RCT found that tocilizumab, an IL-6 receptor blocker, showed a non-significant but clinically suggestive pattern of improvement in difficult-to-treat depression linked to low-grade inflammation. The study found that baseline hs-CRP, rather than IL-6, may help identify patients most likely to respond, supporting larger trials of immune-targeted depression care.

22 May 2026

Excess EXO1 protein may drive cancer DNA damage and treatment response

When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that protect and repair DNA in cells.

21 May 2026

Artificial intelligence-based tool could improve multiple myeloma treatment decisions

An artificial intelligence-based tool may help physicians determine which newly diagnosed multiple myeloma patients are most likely to benefit from specific therapies, including immunotherapy and stem cell transplantation.

21 May 2026

Scientists discover how vitamin K pathway regulates bone remodeling

Bone is continuously renewed through a process known as bone remodeling, in which osteoblasts (bone-forming cells) build new bone, while osteoclasts (bone-resorbing cells) remove older mineralized tissue.

21 May 2026

Fluid viscosity drives mechanical memory and invasion in glioblastoma

Most cancer studies focus on chemical signals or stiff tumor surroundings, but the stickiness of the fluid itself has received little attention.

20 May 2026

Women may face greater cognitive impact from dementia risk factors

Researchers from the University of California San Diego School of Medicine found that women not only experience a higher burden of certain modifiable dementia risk factors, but also appear more vulnerable to their effects on cognitive function.

20 May 2026

Click chemistry advances precision oncology by merging imaging and therapyly

Conventional cancer treatments like chemotherapy often struggle with poor targeting, leading to severe systemic toxicity and drug resistance.

19 May 2026

Precision calcium signaling control may improve future CAR-T therapies

Calcium is widely known for its role in maintaining strong bones and teeth, but it is also one of the body's most important cellular messengers.

19 May 2026

Thermo Fisher Scientific expands global biobank leadership through strategic collaboration with PRECISE-SG100K Singapore to advance population-scale proteomics

Thermo Fisher Scientific Inc., the world leader in serving science, today announced a strategic collaboration with Precision Health Research, Singapore (PRECISE) to advance the PRECISE-SG100K study, one of the region’s most ambitious and diverse population-scale biobank initiatives.

From Olink®- Part of Thermo Fisher Scientific 19 May 2026

Multi-institutional trial explores new lifeline for advanced prostate patients

For men with advanced prostate cancer that no longer responds to standard hormone therapies, treatment options are limited – and time matters. As the disease progresses, the window for effective, less intensive treatments begins to close.

15 May 2026

Evidence shows RF-TC improves seizure control by altering brain networks

Drug-resistant epilepsy affects millions of people worldwide and remains one of the most difficult neurological disorders to treat. For patients whose seizures continue despite medication, surgical removal of seizure-causing tissue can be effective.

15 May 2026

New technology reveals how RNA shapes influence protein production and stability

Researchers from A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a new method, called 'sm-PORE-cupine', to study individual RNA molecules and reveal how their structures influence gene regulation, a fundamental process that affects how cells function in health and disease.

15 May 2026

Stanford scientists map the molecular diversity of different global populations

Researchers at the Stanford School of Medicine have found that ethnicity and geography may influence human molecular makeup - from metabolism and immunity to gut microbiota and biological aging.

14 May 2026

Dual-pathway protein degradation approach could improve cancer treatment

Targeted protein degradation has become one of the most promising strategies in modern drug discovery, enabling scientists to eliminate disease-causing proteins instead of merely blocking them.

12 May 2026

Researchers uncover sex-specific metabolic patterns in ocular tissues

As a highly differentiated sensory organ, the maintenance of the eye's physiological functions relies on rigorous metabolic regulation.

11 May 2026

Targeted mitochondrial therapy accelerates healing of diabetic chronic wounds

Impaired mitophagy and the accumulation of damaged mitochondria are key drivers of endothelial cell (EC)dysfunction in diabetic wounds.

10 May 2026

A brain-based approach may improve smoking cessation treatment success

For many people who smoke, quitting is not just a matter of willpower. It is a tug-of-war in the brain – between the pull of reward and the ability to resist.

8 May 2026

Study reveals why women face higher autoimmune disease risks

Ahead of World Lupus Day on May 10, new research from the Garvan Institute of Medical Research and UNSW Sydney helps explain why women are significantly more likely to be diagnosed with an autoimmune disease – a condition where the immune system misfires and mistakenly attacks the body's own healthy tissues.

7 May 2026