Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

New computational tool uncovers hidden genetic mutations in proteins

Scientists at UCLA and the University of Toronto have developed an advanced computational tool, called moPepGen, that helps identify previously invisible genetic mutations in proteins, unlocking new possibilities in cancer research and beyond.

16 Jun 2025

Redefining health science in the age of exposomics

We live in the age of -omics. We have genomics to study complete sets of DNA. We have proteomics focused on all the proteins within our cells.

13 Jun 2025

Small weight loss leads to big gains in heart health

Even without weight loss, healthy lifestyle changes enhance heart health. This study highlights the importance of habits for cardiometabolic improvement.

9 Jun 2025

New Japanese database reveals how gut microbes and diet connect

Researchers have launched the NIBN Japan Microbiome Database, featuring over 2,000 gut microbiome profiles from healthy Japanese adults with extensive lifestyle and dietary metadata. This resource aims to accelerate microbiome-health research and enable precision medicine insights.

5 Jun 2025

Key proteins and pathways drive the success of CAR-T cell therapy

A study conducted by researchers at the Center for Cell-Based Therapy (CTC) highlights key proteins and signaling pathways involved in the efficacy of immunotherapy based on CAR-T cells (lymphocytes modified in the laboratory to fight cancer).

4 Jun 2025

Study uncovers how HSV-1 disables the brain's antiviral defense

Infections caused by herpes simplex virus type 1 (HSV-1) can lead to HSV-1 encephalitis-a rare but deadly condition that inflames the brain.

3 Jun 2025

What drives insulin resistance? Proteomics reveals key pathways in human skeletal muscle

Identifying proteomic signatures of insulin resistance in fasting muscle offers insights for personalized type 2 diabetes therapies based on molecular profiles.

30 May 2025

University of Houston receives $3 million to set up a Cancer Immunotherapy Biomarker Core

As part of a $93 million grant package, the Cancer Prevention and Research Institute of Texas, known for funding groundbreaking projects, has awarded the University of Houston $3 million to set up a Cancer Immunotherapy Biomarker Core.

27 May 2025

Scientists discover unique molecular fingerprints of insulin resistance

Scientists have unearthed surprising details about how our bodies handle insulin – the hormone that plays a crucial role in regulating blood sugar and developing diabetes.

27 May 2025

Early statin therapy reduces heart attack and stroke risk in diabetes patients

Taking a statin medication is an effective, safe, and low-cost way to lower cholesterol and reduce risk of cardiovascular events.

27 May 2025

New blood test speeds up diagnosis of rare childhood diseases

A new, rapid testing method will greatly help the diagnosis of rare diseases in babies and children, according to research to be presented to the annual conference of the European Society of Human Genetics today (Monday).

25 May 2025

Unlocking the secrets of human longevity and healthy aging

Human healthy aging and longevity are complex phenomena influenced by a dynamic interplay of genetic, epigenetic, metabolic, immune, and environmental factors.

22 May 2025

Evolution of malaria protein family offers new drug targets

Researchers from the Francis Crick Institute and the Gulbenkian Institute for Molecular Medicine (GIMM) have shown that the evolution of a family of exported proteins in the malaria-causing parasite Plasmodium falciparum enabled it to infect humans.

19 May 2025

New stem cell model replicates human amniotic sac development

Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four weeks after fertilization.

15 May 2025

Multiple laboratory techniques can provide a wealth of knowledge about brain cancer

Clinicians from the Johns Hopkins Kimmel Cancer Center and four other institutions have demonstrated that doctors can gain a wealth of knowledge about a patient's cancer by using multiple laboratory techniques to study tumor tissue taken from needle biopsies of glioblastoma, a highly aggressive form of brain cancer.

14 May 2025

Researchers target weakness in pathogens causing tropical diseases

Researchers are zeroing in on the Achilles’ heel of pathogens that cause Chagas disease, sleeping sickness and leishmaniasis.

8 May 2025

Gene deletion in wheat lowers allergenic proteins while maintaining bread quality

Wheat is a major source of calories, carbohydrates and protein worldwide, and its distinctive gluten proteins are what gives bread and pasta dough texture and elasticity.

5 May 2025

Study links pregnancy specific genes to poorer lung cancer outcomes in women

Lung cancer can co-opt genes that normally help a fetus develop and evade the mother's immune system. And while these pregnancy-specific glycoproteins (PSGs) can get activated in the cancers of both men and women, female patients had poorer outcomes, a Memorial Sloan Kettering Cancer Center (MSK) research team has found.

29 Apr 2025

A journey through science, software, and innovation: Insights from the Bruker software team

Follow Bruker's experts as they discuss the SCRUM approach to software development in the scientific industry.

From Bruker Daltonics 29 Apr 2025

Biodesix partner, Friends of Cancer Research, publishes data in Clinical Cancer Research, demonstrating strong association between ctDNA changes and treatment outcomes for patients with solid tumor types

Biodesix, Inc, a leading diagnostics solutions company, and Bio-Rad Laboratories, a global leader in life science research and diagnostics products, contributed to new research findings from Friends of Cancer Research's (Friends') ctMoniTR Project, recently published in Clinical Cancer Research (CCR). The findings demonstrate a strong association between changes in levels of circulating tumor DNA (ctDNA) and treatment outcomes, offering the potential for integration of ctDNA analysis in therapeutic development programs, and clinical cancer care.

23 Apr 2025