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Ethyl lauroyl arginine hydrochloride (ELAH) nasal spray as potent antiviral against SARS-CoV-2

Researchers evaluate the virucidal effects of ELAH against SARS-CoV-2 and human coronavirus-229E in a nasal spray formulation.

15 Mar 2022

Study explores neutralization of SARS-CoV-2 Omicron variant by subunit vaccine boosters

A new study assessed the neutralization induced by subunit vaccine boosters specific for the SARS-CoV-2 Omicron variant of concern.

14 Mar 2022

Factors influencing cross-protective serological immunity against SARS-CoV-2 variants in Asians

Researchers assessed the impact of demographic variability on the Pfizer/BioNTech BNT162b2 vaccine-induced serological immunity against SARS-CoV-2 variants of concern and variants of interest.

14 Mar 2022

Potent pan-β-CoV human monoclonal antibody has in vivo activity in multiple animal models

Researchers evaluated the efficacy of viral spike domain 2-specific human monoclonal antibodies delivered intranasally, against all beta coronaviruses in hamsters and mice.

11 Mar 2022

Natural SARS-CoV-2 infection-induced anti-spike antibody responses

Researchers demonstrated the anti-spike antibody response to SARS-CoV-2 infection and further estimated the acute SARS-CoV-2 infection-induced Ab activity against recently emerged variants like Omicron.

10 Mar 2022

Cross-species infectivity of SARS-CoV-2 variants correlated with prevalence

New research discusses the role of mutations in the receptor-binding domain of the spike protein in the generation of antibody resistance and loss of vaccine efficacy.

10 Mar 2022

Identification of a rapid test for SARS-CoV-2 neutralization via antibodies and nanobodies

Researchers presented a technique called rapid in vitro inhibition assay (RIVIA), whereby potential SARS-CoV-2 antibody and nanobody candidates can be rapidly screened.

8 Mar 2022

Omicron-specific mRNA vaccine generates immune responses in mice, hamsters and Macaques

Researchers develop an Omicron variant mRNA vaccine that is be more potent in generating nAbs as compared to other available vaccines.

6 Mar 2022

Angiotensin-converting enzyme 2-based mutant decoy effectively reduces COVID-19 in mice

Researchers engineered a mutant ACE2 decoy that effectively protected human lung epithelia from SARS-CoV-2 infection by competitively binding to its spike protein.

3 Mar 2022

8G3 broad-spectrum antibody effective against all SARS-CoV-2 variants, including Omicron

Researchers assess the efficacy of 8G3, a B-cell neutralizing antibody against SARS-CoV-2 variants, including the most recent Omicron variant.

3 Mar 2022

How effective is mRNA vaccination in multiple myeloma patients?

In a new study, researchers have been investigating the protection offered by the SARS-CoV-2 vaccine in patients suffering from multiple myeloma.

2 Mar 2022

Emergence of SARS-CoV-2 Omicron likely due to immune selective pressure

A new study discusses the emergence of new variants of SARS-CoV-2 that can escape antibody-mediated neutralization, as opposed to other Sarbecoviruses.

27 Feb 2022

A promising new vaccine for SARS-CoV-2 and influenza

Researchers create a vaccine candidate that could protect against both SARS-CoV-2 and IAVs.

27 Feb 2022

Immunomolecular detection method to rapidly and accurately detect complete SARS-CoV-2 virions

Researchers developed a hybrid assay incorporating immunological antibody-based viral spike protein capture with molecular nucleic acid amplification by qRT-PCR.

24 Feb 2022

Pre-existing B-cell immunity against SARS-CoV-2 not detected in pre-pandemic samples

A recent study investigates samples solated from unexposed individuals pre-pandemic to determine the presence of pre-existing SARS-CoV-2 B-cell immunity.

22 Feb 2022

Study provides a potent biparatopic antibody against all SARS-CoV-2 variants of concern

Researchers demonstrated the potent neutralization of SARS-CoV-2 VOCs, including Omicron by the biparatopic human heavy chain variable domain.

22 Feb 2022

Novel ACE2-blocking antibody protects against all SARS-CoV-2 VOCs

Researchers identify 87G7, a SARS-CoV-2 neutralizing human monoclonal antibody with remarkable broad-spectrum neutralization and protection efficacy.

21 Feb 2022

Study reports potently neutralizing mucosal IgA in saliva of BNT162b2 vaccine recipients

researchers determine the strong neutralizing mucosal component emanating from intramuscular administration of an mRNA vaccine.