Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Integrated NGS system can deliver accurate, genomics-based diagnoses to accelerate treatment for myeloid neoplasms

Identifying recurrent genetic alterations in myeloid neoplasms has improved diagnosis and expanded targeted treatments available to patients. However, treatment initiation can be delayed by the variable and lengthy turnaround times involved in testing for these alterations.

7 Feb 2023

High-fat diet allows the immune system to eliminate a parasitic worm from the intestine

Scientists have discovered that a high-fat diet allows the immune system to eliminate a parasitic worm which is a major cause of death and illness in the developing world.

7 Feb 2023

What do gut microbiota have to do with Alzheimer's and dementia?

Researchers explore the preventive and therapeutic potential of gut microbiome modulation in the treatment of Alzheimer’s disease.

6 Feb 2023

New type of immunotherapy effective in mice with ovarian cancer

CAR T-cell therapy, a certain kind of cancer treatment in which the immune system's T cells are programmed to attack tumor cells, is effective in mice with ovarian cancer, according to a study published in The Journal for ImmunoTherapy of Cancer.

6 Feb 2023

Breakthrough technology identifies rare brain tumor cell "spies" disguised as normal cells

Researchers at the Hong Kong University of Science and Technology developed a novel technology which allows genomic DNA and RNA sequencing to be carried out simultaneously in single cells of both frozen and fresh tissues, and identified rare brain tumor cell "spies" disguised as normal cells with this method.

3 Feb 2023

Cryo-EM reveals the structure of hnRNPDL-2 protein fibrils associated with limb-girdle muscular dystrophy

Limb-girdle muscular dystrophy type 3 (LGMD D3) is a rare disease causing progressive muscle weakness, caused by point mutations in the hnRNPDL-2 protein.

3 Feb 2023

Partially quasi-programmed diseases can be delayed by slowing aging

A new research perspective was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 2, entitled, "Are menopause, aging and prostate cancer diseases?"

3 Feb 2023

FSU psychologist wins NIA grant to treat anxiety in older adults with Alzheimer's, cognitive impairment

For the more than 6 million Americans living with Alzheimer's disease, related dementias, or mild cognitive impairment, anxiety is often an accompanying challenge.

3 Feb 2023

Decision guide provides specific guidelines for swallowing care after extubation

A multidisciplinary group at ECU Health Medical Center in Greenville, North Carolina, developed a decision guide to provide healthcare teams with specific guidelines for swallowing care after extubation.

2 Feb 2023

CuSTOM; Creating a healthier society by accelerating the translation of organoid technology

In this interview, we speak to Magdalena Kasendra at the CuSTOM Accelerator, about the organoid technology and how it has the power the revolutionize healthcare.

From Society for Laboratory Automation and Screening (SLAS) 1 Feb 2023

The impact of common viral infections on blood-brain barrier function and insulin sensitivity

A new study discusses the impact of several human viruses on blood-brain barrier function and insulin sensitivity.

31 Jan 2023

Study finds link between tumor microbiome and immune system in sarcoma patients

In a significant new study, UC Davis Comprehensive Cancer Center researchers have uncovered a link between a patient's microbiome and their immune system that can potentially be used to improve the treatment of soft tissue sarcoma.

30 Jan 2023

Researchers develop a new smartphone-based tool to detect visual impairment in young children

Researchers conducted a prospective, multicenter, observational study between 14 January 2020 and 30 January 2022 in China.

30 Jan 2023

Doctoral research presents predictive value of biomarkers for inflammatory bowel diseases

Under the supervision of four professors from the UMCG departments of Gastroenterology and Hepatology and Pathology and Medical Biology, Bourgonje conducted doctoral research on the predictive value of biomarkers for inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis.

29 Jan 2023

Activated neutrophils can become potent cancer fighters

Elevated levels of immune cells, called neutrophils, in tumors have been associated with poor outcomes in people with cancer.

27 Jan 2023

Disruption of the blood-brain barrier due to long COVID

Researchers explored the destruction of the blood-brain barrier (BBB) due to cognitive impairment associated with long coronavirus disease (COVID).

27 Jan 2023

PLK1-mTOR axis may be a promising therapeutic target for sepsis, study suggests

Sepsis, one of the most acute and serious disease complications in the intensive care unit, is caused by various infections and results in life-threatening organ dysfunction.

26 Jan 2023

Researchers discover the impact of microRNA on inflammation in lupus

A group of researchers from the Graduate School of Medicine at Nagoya University in Japan have discovered the impact of microRNA (miRNA) on inflammation in lupus in mice.

26 Jan 2023

Altered gut microbiome plays a major role in the progression of endometriosis in animal model

About 196 million women worldwide suffer from endometriosis, a condition that typically causes pelvic pain and infertility.

25 Jan 2023

F-box gene mediates dietary restriction effects on extending the health span of C. elegans

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 1, entitled, "The innate immune signaling component FBXC-58 mediates dietary restriction effects on healthy aging in Caenorhabditis elegans."

25 Jan 2023

Pathology News and Research

Further Reading

Integrated NGS system can deliver accurate, genomics-based diagnoses to accelerate treatment for myeloid neoplasms

High-fat diet allows the immune system to eliminate a parasitic worm from the intestine

What do gut microbiota have to do with Alzheimer's and dementia?

New type of immunotherapy effective in mice with ovarian cancer

Breakthrough technology identifies rare brain tumor cell "spies" disguised as normal cells

Cryo-EM reveals the structure of hnRNPDL-2 protein fibrils associated with limb-girdle muscular dystrophy

Partially quasi-programmed diseases can be delayed by slowing aging

FSU psychologist wins NIA grant to treat anxiety in older adults with Alzheimer's, cognitive impairment

Decision guide provides specific guidelines for swallowing care after extubation

CuSTOM; Creating a healthier society by accelerating the translation of organoid technology

The impact of common viral infections on blood-brain barrier function and insulin sensitivity

Study finds link between tumor microbiome and immune system in sarcoma patients

Researchers develop a new smartphone-based tool to detect visual impairment in young children

Doctoral research presents predictive value of biomarkers for inflammatory bowel diseases

Activated neutrophils can become potent cancer fighters

Disruption of the blood-brain barrier due to long COVID

PLK1-mTOR axis may be a promising therapeutic target for sepsis, study suggests

Researchers discover the impact of microRNA on inflammation in lupus

Altered gut microbiome plays a major role in the progression of endometriosis in animal model

F-box gene mediates dietary restriction effects on extending the health span of C. elegans

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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