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Researchers design novel small antibody fragment with improved crystallizability

Antibodies are a powerful weapon system in defending our body against invaders such as bacteria and viruses. Each antibody consists of four polypeptide chains: two heavy chains and two light chains joined to form a Y-shaped molecule.

21 Sep 2017

BMC researchers studying possibility of weight loss drugs to combat cocaine addiction

Boston Medical Center's psychiatry team is studying a drug called lorcaserin, which targets the brain's serotonin receptors and could help reduce cocaine cravings as well as dampen the rewards associated with taking cocaine.

21 Sep 2017

UTMB scientists gain new insights into factors that lead to preterm birth

A group of scientists led by Ramkumar Menon at The University of Texas Medical Branch at Galveston has gained new insights into what factors lead to preterm birth. This study is currently available in The American Journal of Pathology.

21 Sep 2017

Regeneration ability may lie with the body's innate immune system, study shows

The answer to regenerative medicine's most compelling question -- why some organisms can regenerate major body parts such as hearts and limbs while others, such as humans, cannot -- may lie with the body's innate immune system, according to a new study of heart regeneration in the axolotl, or Mexican salamander, an organism that takes the prize as nature's champion of regeneration.

21 Sep 2017

First duodenoscope with disposable distal cap approved by FDA

The U.S. Food and Drug Administration today cleared the first duodenoscope with a disposable distal cap, a new feature that will improve access for cleaning and reprocessing.

20 Sep 2017

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

University of Maryland School of Medicine researchers are investigating a new approach to treat high-risk soft-tissue sarcomas by combining two immunotherapy drugs with radiation therapy to stimulate the immune system to destroy the main tumor as well as leftover microscopic cancer cells that may seed other tumors.

20 Sep 2017

Oxytocin promotes avoidance of unfamiliar situations after negative social interactions

Before you shop for the "cuddle" hormone oxytocin to relieve stress and enhance your social life, read this: a new study from the University of California, Davis, suggests that sometimes, blocking the action of oxytocin in the brain may be a better option.

20 Sep 2017

Penn researchers identify new way to target enzyme crucial to tumor growth, develop new drugs

Opening up a new pathway to fight cancer, researchers at the University of Pennsylvania have found a way to target an enzyme that is crucial to tumor growth while also blocking the mechanism that has made past attempts to target that enzyme resistant to treatment.

20 Sep 2017

Inactivation of Capicua gene leads to formation of T-ALL tumors in mice, researchers find

Researchers at the Spanish National Cancer Research Centre have discovered a genetic alteration that is directly involved in at least 10% of cases of one of the most common cancers in children, T-cell acute lymphoblastic leukemia.

20 Sep 2017

Young people taking anti-epileptic drugs experience bone health issues, study finds

In a study published in Epilepsia, young people taking anti-epileptic drugs experienced elevated rates of bone fractures and had reductions in tibial bone mineral density and lower limb muscle force.

20 Sep 2017

Study may provide insights into treating autism and other neuropsychiatric disorders

Alterations in a naturally occurring chemical in the brain called serotonin have been linked to a number of neuropsychiatric disorders including depression, anxiety, obsessive-compulsive disorder as well as autism spectrum disorder (ASD).

20 Sep 2017

'Small intestinal permeable peptides' improve biopharmaceuticals absorption in digestive tract

Biopharmaceuticals, medium- and high-molecular weight biologically active macromolecules, are not easily absorbed by the small intestine, the main organ responsible for gastrointestinal absorption, resulting in a bottleneck for oral administration type biopharmaceutical development.

20 Sep 2017

Researchers receive $11.5 million program project grant to eliminate drug resistant malaria

Texas Biomedical Research Institute researchers, Dr. Tim Anderson and Dr. Ian Cheeseman, have partnered with researchers at the University of Notre Dame and the Center for Infectious Disease Research in Seattle to pursue studies in drug resistant malaria.

20 Sep 2017

Alcohol use may induce changes to cholesterol-regulating gene

In an analysis of the epigenomes of people and mice, researchers at Johns Hopkins Medicine and the National Institutes of Health report that drinking alcohol may induce changes to a cholesterol-regulating gene.

20 Sep 2017

New collaboration could lead to novel drugs that address unmet medical needs

Southern Research and the University of Tennessee Health Science Center have formed a partnership to advance promising research that could lead to new drugs that address unmet medical needs.

20 Sep 2017

WHO report shows serious lack of new antibiotics to combat drug-resistant infections

A report, Antibacterial agents in clinical development - an analysis of the antibacterial clinical development pipeline, including tuberculosis, launched today by WHO shows a serious lack of new antibiotics under development to combat the growing threat of antimicrobial resistance.

20 Sep 2017

Cancer patients less likely to receive evidence-based treatments for heart attack

Treatment of heart attack patients depends on their history of cancer, according to research published today in European Heart Journal: Acute Cardiovascular Care.

20 Sep 2017

Comprehensive risk assessment can help prevent fall injuries among seniors

Every year, millions of senior citizens fall - threatening their health, independence and even their lives. Fall injuries also rack up $31 billion annually in medical expenses, which is expected to rise as 10,000 people in the U.S. turn 65 every day.

20 Sep 2017

Discovery reveals new role for endoplasmic reticulum-associated degradation

The discovery of a puddle of mouse urine seems like a strange scientific "eureka" moment. However, for one team of researchers, that's exactly what led to a new discovery.

20 Sep 2017

Researchers develop new model to better simulate blood brain barrier for study of diseases

Scientists have helped provide a way to better understand how to enable drugs to enter the brain and how cancer cells make it past the blood brain barrier. The brain is protected by the near-impermeable blood brain barrier, a fortress which protects the brain but which also prevents the treatment of brain diseases, including brain tumors.

19 Sep 2017

Drugs News and Research

Researchers design novel small antibody fragment with improved crystallizability

BMC researchers studying possibility of weight loss drugs to combat cocaine addiction

UTMB scientists gain new insights into factors that lead to preterm birth

Regeneration ability may lie with the body's innate immune system, study shows

First duodenoscope with disposable distal cap approved by FDA

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

Oxytocin promotes avoidance of unfamiliar situations after negative social interactions

Penn researchers identify new way to target enzyme crucial to tumor growth, develop new drugs

Inactivation of Capicua gene leads to formation of T-ALL tumors in mice, researchers find

Young people taking anti-epileptic drugs experience bone health issues, study finds

Study may provide insights into treating autism and other neuropsychiatric disorders

'Small intestinal permeable peptides' improve biopharmaceuticals absorption in digestive tract

Researchers receive $11.5 million program project grant to eliminate drug resistant malaria

Alcohol use may induce changes to cholesterol-regulating gene

New collaboration could lead to novel drugs that address unmet medical needs

WHO report shows serious lack of new antibiotics to combat drug-resistant infections

Cancer patients less likely to receive evidence-based treatments for heart attack

Comprehensive risk assessment can help prevent fall injuries among seniors

Discovery reveals new role for endoplasmic reticulum-associated degradation

Researchers develop new model to better simulate blood brain barrier for study of diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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