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Lowering blood sugar reduces heart risk in prediabetes

Lowering blood sugar levels halves the likelihood of serious heart problems in people with prediabetes.

12 Dec 2025

Dinutuximab beta plus chemotherapy shrinks neuroblastoma tumors in children

Children with a rare form of cancer called neuroblastoma which hasn't responded to initial treatment or that has relapsed may benefit from adding antibody treatment to usual chemotherapy, according to new results from a clinical trial.

12 Dec 2025

UC Irvine receives funding for clinical trial of neural stem cell therapy for Huntington's disease

Leslie M. Thompson, Donald Bren Professor of psychiatry and human behavior as well as neurobiology and behavior at the University of California, Irvine, has received an $11,999,933 grant from the California Institute for Regenerative Medicine for an unprecedented clinical trial of a novel neural stem cell therapy for Huntington's disease.

12 Dec 2025

Etomidate proves safer than ketamine for emergency intubations

Doctors treating seriously ill patients in an emergency setting may want to give the sedative etomidate, rather than ketamine, while placing a breathing tube, according to a randomized trial published Dec. 9 in the New England Journal of Medicine.

12 Dec 2025

Over-contracted gut muscles drive gastrointestinal symptoms in myotonic dystrophy

Myotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy, affecting about 1 in 8,000 people. While it is well known for causing muscle weakness and stiffness, DM1 also affects other organs, including the brain, heart and gastrointestinal (GI) tract.

12 Dec 2025

Combining inhibitors and chemotherapy enhances treatment for aggressive leukemia subtypes

While patients with acute myeloid leukemia (AML) are routinely treated with chemotherapy and other cell-killing therapies, existing options do not lead to favorable clinical outcomes in all patients.

12 Dec 2025

Rural health providers hit by $100K Trump visa fee

More than 30 people have applied for a lab technician job at West River Health Services in Hettinger, North Dakota, a thousand-person town in the rural southwestern part of the state.

12 Dec 2025

Interdisciplinary project aims reduce noise exposure for premature children in neonatal care

Premature babies are particularly susceptible to strong sensory impressions and high sound levels from the incubator. Now researchers will look at what can be done to protect children's hearing and development.

12 Dec 2025

Pediatric critical care survivors often lack prompt primary care follow up

When the unthinkable happens and a child is left critically ill or injured, the miracle workers in pediatric intensive care units around the country work tirelessly to save their lives.

12 Dec 2025

Nighttime heart attacks cause less damage due to neutrophil circadian rhythms

Heart attacks that occur at night are less severe than those that strike during the day. A new study from the Centro Nacional de Investigaciones Cardiovasculares (CNIC) explains why. Published in the Journal of Experimental Medicine, the study led by Dr. Andrés Hidalgo's group at the CNIC shows that neutrophils-a type of white blood cell-have an internal clock that regulates their aggressiveness throughout the day and determines the extent of damage they cause to the heart after a heart attack.

12 Dec 2025

Tianjin grading system improves prognosis prediction in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is notoriously difficult to treat due to its aggressive nature and limited prognostic tools.

12 Dec 2025

Metabolic imaging enables early response prediction in bone-dominant metastatic breast cancer

A prospective, multicenter cancer clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) has validated an improved method for predicting treatment benefits in patients with hormone receptor-positive (HR+) metastatic breast cancer that has spread primarily or exclusively to the bones.

12 Dec 2025

Distinct transcriptomic profiles guide early development of maxillary and mandibular teeth

The interaction between genetics and tissue environment shapes how individual teeth form in different regions of the jaw.

12 Dec 2025

Maxillary nerve block may reduce perioperative opioid consumption in pediatric primary clefts

For infants undergoing cleft palate surgery, local anesthetic injection targeting the maxillary nerve of the face may reduce or eliminate the need for opioid medications to control postoperative pain, reports a study in The Journal of Craniofacial Surgery.

12 Dec 2025

Menopausal hormone therapy shows no added breast cancer risk for BRCA carriers

Using menopausal hormone therapy (MHT) was not associated with an increased risk of breast cancer in women with inherited mutations in the BRCA1 or BRCA2 genes, according to the results of a matched prospective analysis presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

12 Dec 2025

Hospital News and Research

Lowering blood sugar reduces heart risk in prediabetes

Dinutuximab beta plus chemotherapy shrinks neuroblastoma tumors in children

UC Irvine receives funding for clinical trial of neural stem cell therapy for Huntington's disease

Etomidate proves safer than ketamine for emergency intubations

Over-contracted gut muscles drive gastrointestinal symptoms in myotonic dystrophy

Combining inhibitors and chemotherapy enhances treatment for aggressive leukemia subtypes

Rural health providers hit by $100K Trump visa fee

Interdisciplinary project aims reduce noise exposure for premature children in neonatal care

Pediatric critical care survivors often lack prompt primary care follow up

Nighttime heart attacks cause less damage due to neutrophil circadian rhythms

Tianjin grading system improves prognosis prediction in pancreatic cancer

Metabolic imaging enables early response prediction in bone-dominant metastatic breast cancer

Distinct transcriptomic profiles guide early development of maxillary and mandibular teeth

Maxillary nerve block may reduce perioperative opioid consumption in pediatric primary clefts

Menopausal hormone therapy shows no added breast cancer risk for BRCA carriers

Researchers identify chromatin accessibility changes driving stem cell transformation in MDS

Increased epicardial fat volume linked to greater myocardial injury after infarction

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Smoke from Canadian wildfires linked to worse asthma symptoms in children

Proton therapy improves survival in oropharyngeal cancer patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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