Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

CNB-CSIC vaccine fully protects against SARS-CoV-2 infection of the brain

In a recent study published in the journal Nature Neuroscience, researchers in Spain described the effectiveness of a modified vaccinia virus Ankara (MVA) vector severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidate in protecting against SARS-CoV-2 infection in the brain using a mouse model.

12 Jan 2023

Newly revised classification tool for standardized diagnostic reporting of melanocytic lesions

With the growing number of skin biopsies performed annually for suspected melanoma, a simple, easily understood standardized classification system for melanocytic lesions is increasingly important to aid pathologists and clinicians who examine millions of tissue samples each year and to alleviate patient confusion and anxiety.

11 Jan 2023

Study reveals how inflammation alters the tumor microenvironment in acute myeloid leukemia

Severe inflammation weakens the body's ability to kill cancerous blood cells in people with acute myeloid leukemia (AML), a new study shows.

11 Jan 2023

Study may help explain how excess weight can contribute to diabetes

People who are overweight or obese have a significantly increased risk of developing diabetes, but exactly how that happens is not well understood.

11 Jan 2023

RNAs may be a promising biomarker and therapeutic target for ischemic stroke

RUDN doctors analyzed the latest research on the use of RNA for the treatment and diagnosis of ischemic stroke.

10 Jan 2023

Protein Medin: A new treatment target for Alzheimer's

A recent study published in the journal Nature reported the co-aggregation of medin, a fragment of lactadherin, with vascular amyloid-β in Alzheimer’s disease (AD).

10 Jan 2023

Can diets reverse or delay aging?

A new study published in the journal Science aimed to summarize the commonly studied anti-aging dietary interventions and their impact on human health and longevity.

10 Jan 2023

Newly identified gene drives development of the second most common type of lung carcinoma

A team led by researchers at NYU Langone Health's Perlmutter Cancer Center has identified a gene that drives development of the second most common type of lung carcinoma, offering greater insight into how the disease might someday be treated.

9 Jan 2023

Marine plankton samples can help study the connections between ocean pollution and rates of chronic illnesses

Using samples from an almost century-old, ongoing survey of marine plankton, researchers at University of California San Diego School of Medicine suggest that rising levels of manmade chemicals found in parts of the world's oceans might be used to monitor the impact of human activity on ecosystem health, and may one day be used to study the connections between ocean pollution and land-based rates of childhood and adult chronic illnesses.

6 Jan 2023

Researchers show how liver cancer cells hijack circadian clock machinery to divide and spread

The most common type of liver cancer, hepatocellular carcinoma (HCC), is already the third leading cause of cancer-related deaths globally - and cases are on the rise, both in the U.S. and worldwide.

6 Jan 2023

Study links epigenetic biological aging and aberrations in neural oscillatory activity in people with HIV

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 24, entitled, "Epigenetic aging is associated with aberrant neural oscillatory dynamics serving visuospatial processing in people with HIV."

6 Jan 2023

Scientists pinpoint the routes taken by SARS-CoV-2 to enter and exit cells in our nasal cavity

Somebody just coughed on you. On a plane. At a dinner party. In a supermarket line. If only there were a "morning after" nasal spray that could knock out respiratory viruses' ability to colonize your nose and throat.

5 Jan 2023

Study supports association of the ε4 alleles and polygenic profiles with Alzheimer’s disease biomarkers

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 24, entitled, "Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease biomarkers."

3 Jan 2023

Researchers identify novel gene mechanism in most aggressive kidney cancers

In a new study from the Johns Hopkins Kimmel Cancer Center, researchers described a novel mechanism of tumor formation in kidney cancers driven by overexpression of the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway with loss of the tuberous sclerosis complex (TSC) tumor suppressor gene.

3 Jan 2023

Age-related macular degeneration reported to confer higher risk of severe SARS-CoV-2 infection

Recent evidence has emerged to suggest that age-related macular degeneration (AMD) is a clinical risk factor for increased risk for infection and mortality.

3 Jan 2023

Advanced MRI tool can reveal new structural insights into atherothrombosis

Atherosclerosis is a long-term arterial vessel wall disease characterized by the build- up of lipid- rich and inflamed plaques.

3 Jan 2023

Why do some people develop persistent lung sequelae after severe COVID-19?

Clinical presentation following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ranges from mild self-limiting illness to severe respiratory failure. Many studies have analyzed the early acute phases of coronavirus disease 2019(COVID-19), but few focused on the longer-term sequelae following infection.

2 Jan 2023

Pathology News and Research

Further Reading

CNB-CSIC vaccine fully protects against SARS-CoV-2 infection of the brain

Newly revised classification tool for standardized diagnostic reporting of melanocytic lesions

Study reveals how inflammation alters the tumor microenvironment in acute myeloid leukemia

Study may help explain how excess weight can contribute to diabetes

RNAs may be a promising biomarker and therapeutic target for ischemic stroke

Protein Medin: A new treatment target for Alzheimer's

Can diets reverse or delay aging?

Newly identified gene drives development of the second most common type of lung carcinoma

Marine plankton samples can help study the connections between ocean pollution and rates of chronic illnesses

Researchers show how liver cancer cells hijack circadian clock machinery to divide and spread

Study links epigenetic biological aging and aberrations in neural oscillatory activity in people with HIV

Scientists pinpoint the routes taken by SARS-CoV-2 to enter and exit cells in our nasal cavity

Study supports association of the ε4 alleles and polygenic profiles with Alzheimer’s disease biomarkers

Researchers identify novel gene mechanism in most aggressive kidney cancers

Age-related macular degeneration reported to confer higher risk of severe SARS-CoV-2 infection

Advanced MRI tool can reveal new structural insights into atherothrombosis

Why do some people develop persistent lung sequelae after severe COVID-19?

Innovations in expansion microscopy allow unprecedented view of the interior of cells

New method records gene activity patterns and presence of proteins across tissues

Novel experimental approach slows physical decline and extends the lives of roundworms

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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