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Deep-sea bacterial compound triggers pyroptosis to fight cancer

Promoting pyroptosis-an inflammatory form of programmed cell death-has become a promising treatment strategy for cancer.

23 Jul 2025

Republicans call Medicaid rife with fraudsters. This man sees no choice but to break the rules.

As congressional Republicans finalized Medicaid work requirements in President Donald Trump's budget bill, one man who relies on that government-subsidized health coverage was trying to coax his old car to start after an eight-hour shift making sandwiches.

23 Jul 2025

Targeting tumor cell stemness may hold the key to treating colon cancer more effectively

Colon cancer remains a major global health concern, ranking third among the most diagnosed cancers and leading causes of cancer-related death worldwide.

22 Jul 2025

New approach doubles chemotherapy effectiveness by targeting cancer cell memory

In a wholly new approach to cancer treatment, Northwestern University biomedical engineers have doubled the effectiveness of chemotherapy in animal experiments.

22 Jul 2025

Can one drug do it all? Reviewing the expanding clinical universe of GLP-1 agonists

Landmark trials have shown that GLP-1 receptor agonists, originally developed for diabetes and weight loss, also provide significant benefits for cardiovascular, kidney, liver, joint, and sleep-related diseases. These effects extend beyond weight loss, suggesting anti-inflammatory mechanisms with broad potential for managing chronic diseases.

22 Jul 2025

GLP-1 receptor agonists linked to lower dementia risk in type 2 diabetes

GLP-1 receptor agonists, a class of drug used to treat type 2 diabetes, likely trump the widely prescribed metformin for curbing dementia risk in people with the condition, finds the largest study of its kind, published in the open access journal BMJ Open Diabetes Research & Care.

22 Jul 2025

Fad diets and supplements fuel new wave of hidden skin problems, study finds

A new review explains how fad diets and unregulated supplements promoted online can cause serious skin, hair, and nail problems, often before other symptoms appear. Clinicians are urged to recognize these risks and address health misinformation in the digital age.

22 Jul 2025

Dual cancer drugs restore memory and rewire brain cells in Alzheimer’s mouse models

Researchers identified a combination of two existing cancer drugs, letrozole and irinotecan, that reversed Alzheimer’s disease-related changes in brain cell networks and improved memory in mouse models. The study supports a multi-cell-type, network-correcting strategy as a promising path for future Alzheimer’s treatments.

22 Jul 2025

Mitochondrial protein misfolding found to kill pancreatic cells in type 2 diabetes

Aging-related diseases, including cancer, cardiovascular disorders and type 2 diabetes, are associated with defects in protein synthesis and folding.

22 Jul 2025

Cannabis and psychedelics rated most effective for symptom relief by eating disorder patients

A pioneering international survey of people living with eating disorders has found that cannabis and psychedelics, such as 'magic mushrooms' or LSD, were best rated as alleviating symptoms by respondents who self-medicated with the non-prescribed drugs.

22 Jul 2025

New insights reveal how the immune system fights intestinal parasites

New research from the University of Pittsburgh reveals how the immune system defends against intestinal parasitic worms, or helminths, one of the most common infections worldwide in communities with limited access to clean water and sanitation.

22 Jul 2025

New 3D tissue model offers hope for scleroderma treatment

For the 300,000 Americans living with the immune disease scleroderma, better treatments can't come soon enough. The rare and sometimes fatal illness stiffens and scars tissue in organs like the lungs, liver, and kidneys, as well as skin.

22 Jul 2025

New antibody therapy offers hope for fragile patients with Fanconi anemia

An antibody treatment developed at Stanford Medicine successfully prepared patients for stem cell transplants without toxic busulfan chemotherapy or radiation, a phase 1 clinical trial has shown.

22 Jul 2025

PhoreMost demonstrates new approach to rationalize molecular glue drug discovery

PhoreMost Ltd., a next-generation targeted protein degradation (TPD) company progressing a pipeline of degrader therapeutics within oncology and inflammation, today announced the publication of a study demonstrating the capabilities of its high-throughput GlueSEEKER platform to accelerate the design and development of novel molecular glue degraders.

22 Jul 2025

Weight regain observed in patients after ending obesity drug treatment

Patients prescribed drugs to help them lose weight may experience a rebound in weight gain after halting their prescription, finds a meta-analysis published in BMC Medicine.

22 Jul 2025

Australian study uncovers first potential prophylactic treatment against HTLV-1

Around 10 million people globally live with the life-threatening virus HTLV-1. Yet it remains a poorly understood disease that currently has no preventative treatments and no cure.

21 Jul 2025

Muscle-derived vesicles heal damaged cells and reverse disease in new study

Researchers discovered that mitochondria-rich extracellular vesicles (Ti-mitoEVs) from skeletal muscle can deliver healthy mitochondria to damaged cells, restoring energy and promoting tissue repair in mice. The approach reversed acute muscle injury and chronic kidney disease, offering a promising new regenerative therapy.

21 Jul 2025

Study identifies mechanism that helps prevent cancer, neurodegeneration, and premature aging

Researchers at the University of Oxford and Nanyang Technological University, Singapore (NTU Singapore) have uncovered the mechanism by which cells identify and repair a highly toxic form of DNA damage that causes cancer, neurodegeneration, and premature aging.

21 Jul 2025

Muscle loss from GLP-1 drugs could undermine long-term health

Popular GLP-1 drugs help many people drop tremendous amounts of weight, but the drugs fail to provide a key improvement in heart and lung function essential for long-term good health, University of Virginia experts warn in a new paper.

21 Jul 2025

Combination of two cancer drugs could treat the most common form of dementia

A study comparing the gene expression signature of Alzheimer's disease with those elicited by 1,300 approved drugs found a combination of two cancer medications that could treat the most common form of dementia.

21 Jul 2025

Drugs News and Research

Deep-sea bacterial compound triggers pyroptosis to fight cancer

Republicans call Medicaid rife with fraudsters. This man sees no choice but to break the rules.

Targeting tumor cell stemness may hold the key to treating colon cancer more effectively

New approach doubles chemotherapy effectiveness by targeting cancer cell memory

Can one drug do it all? Reviewing the expanding clinical universe of GLP-1 agonists

GLP-1 receptor agonists linked to lower dementia risk in type 2 diabetes

Fad diets and supplements fuel new wave of hidden skin problems, study finds

Dual cancer drugs restore memory and rewire brain cells in Alzheimer’s mouse models

Mitochondrial protein misfolding found to kill pancreatic cells in type 2 diabetes

Cannabis and psychedelics rated most effective for symptom relief by eating disorder patients

New insights reveal how the immune system fights intestinal parasites

New 3D tissue model offers hope for scleroderma treatment

New antibody therapy offers hope for fragile patients with Fanconi anemia

PhoreMost demonstrates new approach to rationalize molecular glue drug discovery

Weight regain observed in patients after ending obesity drug treatment

Australian study uncovers first potential prophylactic treatment against HTLV-1

Muscle-derived vesicles heal damaged cells and reverse disease in new study

Study identifies mechanism that helps prevent cancer, neurodegeneration, and premature aging

Muscle loss from GLP-1 drugs could undermine long-term health

Combination of two cancer drugs could treat the most common form of dementia

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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