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Intravenous iron shows safe and beneficial outcomes for patients with bacterial infection and anemia

Treatment with intravenous (IV) iron significantly improved survival and increased hemoglobin levels in patients with iron-deficiency anemia who were hospitalized for an acute bacterial infection, according to an analysis of data from more than 85,000 patients.

7 Dec 2025

Black patients with AML experience earlier onset and poorer outcomes

Compared with white patients, Black patients with acute myeloid leukemia (AML) were on average more than five years younger at diagnosis, more than 30% more likely to die of their disease, and more than 20% more likely to die of any cause, according to an analysis of data conducted over a 34-year period and supported by the National Cancer Institute (NCI) is a component of the U.S. National Institutes of Health.

7 Dec 2025

Study finds no specific harms linked to hydroxyurea exposure during pregnancy

Taking the sickle cell drug hydroxyurea during or shortly before pregnancy does not appear to cause specific issues in newborns, according to the first prospective study of pregnancies involving hydroxyurea exposure.

7 Dec 2025

Challenges and opportunities in delivering gene therapies for sickle cell disease and beta thalassemia

The first study assessing the real-world commercial roll-out of gene therapies for sickle cell disease and beta thalassemia offers lessons learned to inform best practices as manufacturers and medical centers prepare to meet growing demand for gene therapies in the coming years.

7 Dec 2025

New evidence shows hematopoietic cell transplantation offers durable relief for sickle cell disease

Patients who underwent hematopoietic cell transplantation for sickle cell disease saw high rates of survival without disease symptoms and low rates of severe side effects or complications years after their procedure, according to a new study.

7 Dec 2025

Most sickle cell patients face long delays for recommended pain relief, study shows

A new study finds that only one in three patients visiting emergency departments (EDs) for severe pain associated with sickle cell disease received appropriate opioid-based pain-relieving medications within the first hour as recommended by the American Society of Hematology (ASH) and National Heart, Lung, and Blood Institute (NHLBI).

6 Dec 2025

Exa-cel shows complete success in early pediatric trials for sickle cell disease and beta-thalassemia

Preliminary results from two trials of the gene therapy exagamglogene autotemcel (exa-cel) suggest the therapy offers an effective cure for beta-thalassemia and sickle cell disease in children younger than 12.

6 Dec 2025

Billions still lack essential health services despite worldwide gains in coverage

Since 2000, most countries – across all income levels and regions – have made concurrent progress in expanding health service coverage and reducing the financial hardship associated with health costs, according to a new joint report from the World Health Organization (WHO) and the World Bank Group.

6 Dec 2025

New Lancet case study series highlights how social forces shape patient health

In November, The Lancet, one of the world's most esteemed medical journals, launched a new monthly series of case studies that goes beyond clinical diagnoses to illuminate the social and cultural forces that contribute to each patient's condition.

5 Dec 2025

Study finds mixed reviews of virtual nursing programs among bedside nurses

Hospitals struggling to attract and retain enough registered nurses at the bedside are implementing alternative strategies to ensure patients get needed nursing care.

5 Dec 2025

Tenascin C as a key to restoring muscle regeneration in aging

As we age, the muscles we rely on for daily activities tend to become less reliable. With enough decline, even normal movements such as getting out of bed become risky.

5 Dec 2025

Smoking fewer cigarettes does not eliminate cardiovascular disease risk

In a study funded by the National Heart, Lung, and Blood Institute, new research from Johns Hopkins Medicine adds to existing evidence that smoking fewer cigarettes does not eliminate cardiovascular disease risk, and quitting entirely is the most effective strategy for improving health.

5 Dec 2025

Research examines oral health benefits of toothbrush choice and brushing duration

Real progress in oral health doesn't come from expensive gadgets, but from better daily habits. That is the conclusion of dentist- periodontist Tim Thomassen in his dissertation Oral Disease Prevention, which he will defend on 12 December at the University of Amsterdam.

5 Dec 2025

Health savings accounts, backed by GOP, cover fancy saunas but not insurance premiums

With the tax-free money in a health savings account, a person can pay for eyeglasses or medical exams, as well as a $1,700 baby bassinet or a $300 online parenting workshop.

5 Dec 2025

Pre-workout supplements linked to dangerously short sleep

Pre-workout supplements are associated with lower sleep duration in young Canadians, highlighting the need for guidance on timing and caffeine content.

5 Dec 2025

Engineered herpes virus activates potent immune responses against glioblastoma

Researchers at Mass General Brigham have modified a herpes simplex virus (HSV-1) that stimulates the immune system to attack glioblastoma cells.

4 Dec 2025

Cystic fibrosis patients on triple-drug therapy can safely reduce daily lung treatments

A new multi-site study led by researchers at CU Anschutz shows that people with cystic fibrosis (CF) who start the triple-drug therapy elexacaftor/tezacaftor/ivacaftor (ETI) can safely reduce many of their daily lung treatments while maintaining good health for years.

4 Dec 2025

Scientists reveal how the brain reshapes episodic memories over time

A study from the University of East Anglia is helping scientists better understand how our brains remember past events - and how those memories can change over time.

4 Dec 2025

Long-term air pollution exposure linked to more advanced coronary artery disease

Long-term exposure to common air pollutants is associated with more advanced coronary artery disease-with notable differences between women and men-according to a large-scale study of more than 11,000 adults being presented today at the annual meeting of the Radiological Society of North America (RSNA).

4 Dec 2025

New drug combination shows promise for overcoming resistance in ovarian cancer

Researchers at the University of Colorado Cancer Center have discovered a novel therapy combination that could offer new hope to ovarian cancer patients who do not respond to existing treatments.

4 Dec 2025

Education News and Research

Intravenous iron shows safe and beneficial outcomes for patients with bacterial infection and anemia

Black patients with AML experience earlier onset and poorer outcomes

Study finds no specific harms linked to hydroxyurea exposure during pregnancy

Challenges and opportunities in delivering gene therapies for sickle cell disease and beta thalassemia

New evidence shows hematopoietic cell transplantation offers durable relief for sickle cell disease

Most sickle cell patients face long delays for recommended pain relief, study shows

Exa-cel shows complete success in early pediatric trials for sickle cell disease and beta-thalassemia

Billions still lack essential health services despite worldwide gains in coverage

New Lancet case study series highlights how social forces shape patient health

Study finds mixed reviews of virtual nursing programs among bedside nurses

Tenascin C as a key to restoring muscle regeneration in aging

Smoking fewer cigarettes does not eliminate cardiovascular disease risk

Research examines oral health benefits of toothbrush choice and brushing duration

Health savings accounts, backed by GOP, cover fancy saunas but not insurance premiums

Pre-workout supplements linked to dangerously short sleep

Engineered herpes virus activates potent immune responses against glioblastoma

Cystic fibrosis patients on triple-drug therapy can safely reduce daily lung treatments

Scientists reveal how the brain reshapes episodic memories over time

Long-term air pollution exposure linked to more advanced coronary artery disease

New drug combination shows promise for overcoming resistance in ovarian cancer

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