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Impact of environmental SARS-CoV-2 contamination in residential housing

In a new study, scientists hypothesize that the presence of Corynebacterium and SARS-CoV-2 in surface samples might be associated with skin contamination.

10 Dec 2021

Evolution of the SARS-CoV-2 omicron variant

Study shows that the omicron variant shares a common ancestry with the VOI lambda and has evolved mainly because of non-synonymous mutations.

9 Dec 2021

Rapid antigen detection test for SARS-CoV-2 proves more effective than expected, large study reports

In what is believed to be the largest prospective study of its kind to date - involving some 6,000 patients seen at the Baltimore Convention Center Field Hospital (BCCFH) during a 10-day period around the beginning of 2021 - researchers at Johns Hopkins Medicine, the University of Maryland Medical Center, the University of Maryland School of Medicine and four other collaborators report that a rapid antigen detection test for SARS-CoV-2, the virus that causes COVID-19, proved more effective than expected when compared with virus detection rates using the established standard test, the polymerase chain reaction (PCR) assay.

8 Dec 2021

The antiviral potential of 4′-fluorouridine as an oral treatment against RSV and SARS-CoV-2

New research reports 4’-Fluorouridine (4′-FlU) as an oral antiviral against RSV and SARS-CoV-2.

7 Dec 2021

Cas12a-based bio-sensor for detecting SARS-CoV-2 mutations

Scientists develop an improved biosensor with Cas12a-based CRISPR on-site rapid detection system and discuss its ability to detect SARS-CoV-2 VOCs.

7 Dec 2021

SARS-CoV-2 re-infection from new variant after natural infection

Researchers survey incidences of SARS-CoV-2 infection in both care home staff and residents early in the pandemic.

7 Dec 2021

Delta SARS-CoV-2 variant drove increase in infection numbers in the U.K.

Researchers determine how different the SARS-CoV-2 Delta variant was from the previously dominant Alpha variant.

7 Dec 2021

Area-level variation in infection fatality ratio in the US COVID-19 pandemic

A new preprint describes the infection fatality ratio, a crucial indicator for planning public health programs and shaping policies.

7 Dec 2021

Method for inactivation and direct RT-qPCR of SARS-CoV-2

Researchers from the University of Edinburgh have been exploring ways to optimize this process further, allowing RT-qPCR to work more efficiently by eliminating one of the key steps.

7 Dec 2021

SARS-CoV-2 Delta saliva viral load 15 times that of the wild type

Researchers hypothesize that a higher viral load of SARS-CoV-2 Delta variant in saliva contributes to its high transmissibility.

6 Dec 2021

Colorimetric detection of SARS-CoV-2 viral RNA by an in vitro transcription/translation assay

This work has emphasized the clinical and translational potential of paper-based biosensors.

6 Dec 2021

COVID-19-recovered patients at an increased risk of developing new-onset mental illness

Research suggests that patients who have recovered from COVID-19 were at an increased risk for developing new-onset mental illness.

6 Dec 2021

A new model linking SARS-CoV-2 viral load to infectiousness may guide further testing strategy

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5 Dec 2021

Equipment-free handheld microfluidic injection provides visible readout of SARS-CoV-2 detection

In this paper, a group of researchers from Harvard Medical School, McGill University, and Tianjin University describes an on-chip diagnostic technology for the direct detection of SARS-CoV-2 N protein in nasal samples that combines the advantages of hydrodynamic microfluidic filtration and sandwich immunoassay.

5 Dec 2021

Preclinical data shows enhanced T-cell responses & neutralization of SARS-CoV-2 variants with ImmunityBio heterologous vaccination

A new study supports the hypothesis that heterologous vaccination can provide an increased immune response against virus infection, supporting several other studies that have indicated similar events.

5 Dec 2021

Polymerase News and Research

Impact of environmental SARS-CoV-2 contamination in residential housing

Evolution of the SARS-CoV-2 omicron variant

Rapid antigen detection test for SARS-CoV-2 proves more effective than expected, large study reports

The antiviral potential of 4′-fluorouridine as an oral treatment against RSV and SARS-CoV-2

Cas12a-based bio-sensor for detecting SARS-CoV-2 mutations

SARS-CoV-2 re-infection from new variant after natural infection

Delta SARS-CoV-2 variant drove increase in infection numbers in the U.K.

Area-level variation in infection fatality ratio in the US COVID-19 pandemic

Method for inactivation and direct RT-qPCR of SARS-CoV-2

SARS-CoV-2 Delta saliva viral load 15 times that of the wild type

Colorimetric detection of SARS-CoV-2 viral RNA by an in vitro transcription/translation assay

COVID-19-recovered patients at an increased risk of developing new-onset mental illness

A new model linking SARS-CoV-2 viral load to infectiousness may guide further testing strategy

Equipment-free handheld microfluidic injection provides visible readout of SARS-CoV-2 detection

Preclinical data shows enhanced T-cell responses & neutralization of SARS-CoV-2 variants with ImmunityBio heterologous vaccination

Maternal morbidities and outcomes in pregnant women with COVID-19

Risk of COVID-19 hospitalization among children with markers of uncontrolled asthma

Study finds third dose of BNT162b2 or mRNA-1273 is moderately effective against post-vaccination COVID-19 infection

Hybrid immunity provides the highest and most durable immunity against SARS-CoV-2 infection

Researchers introduce new method for observing cell interactions

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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