Preclinical News and Research

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First fully human ovarian organoids provide insights about female reproductive health and disease

Despite the fact that we all start out as an egg cell in one of our mother's ovaries, these human reproductive organs are surprisingly under-studied.

21 Feb 2023

Ketamine appears to hold promise in treating cocaine-use disorders

As cocaine use continues to climb across the United States, scientists have struggled to develop an effective pharmacological approach to treat the devastating disorder.

20 Feb 2023

Spinal cord stimulation technology instantly improves arm and hand mobility in stroke patients

A neurotechnology that stimulates the spinal cord instantly improves arm and hand mobility, enabling people affected by moderate to severe stroke to conduct their normal daily activities more easily, report researchers from the University of Pittsburgh and Carnegie Mellon University today in Nature Medicine.

20 Feb 2023

UTHSC researchers secure $308,000 grant from Department of Defense for dementia study

Repeated traumatic brain injuries (TBI) in soldiers and military personnel can cause behavioral, neurological, and cognitive effects and lead to dementia.

19 Feb 2023

Ferroptosis could be the key to making effective immunotherapies against liver cancer

Iron-dependent cell death (ferroptosis) is a type of programmed cell death by means of which the body kills off diseased, defective or superfluous cells.

17 Feb 2023

LLNL licensee and collaborators develop novel medicines to combat autoimmune diseases

People afflicted with autoimmune diseases may someday receive help through treatments now under development by a Lawrence Livermore National Laboratory licensee and its' collaborations with two major pharmaceutical companies.

17 Feb 2023

Beckman Coulter Life Sciences presenting at SLAS2023

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, will have a full team of dedicated professionals and informative programming at the upcoming Society for Laboratory Automation and Screening (SLAS) International Conference and Exhibition.

From Beckman Coulter Life Sciences 16 Feb 2023

An oral and on-demand male contraceptive

Researchers identify a soluble adenylyl cyclase (sAC) inhibitor that has the potential to be used as an on-demand oral contraceptive for men.

16 Feb 2023

CHLA researchers receive funding to support studies into diffuse intrinsic pontine glioma

Researchers at Children's Hospital Los Angeles have received a nearly $1 million K08 grant from the National Institutes of Health (NIH) - as well as funding from the U.S. Department of Defense - to support studies into diffuse intrinsic pontine glioma (DIPG), a childhood brain tumor with a 0% survival rate.

16 Feb 2023

Inventia Life Science collaborates with MSD to develop 3D advanced cell models for neurodegenerative disease drug discovery

Inventia Life Science, a world leader in advanced cell models for biomedical research and drug discovery, today announced a collaboration with MSD (tradename of Merck & Co., Inc., Rahway, N.J., USA) using Inventia’s RASTRUM™ 3D cell culture platform.

From Inventia Life Science 16 Feb 2023

Protein degradation approach can be used to hit an ‘undruggable’ target against cancer

The protein STAT5 has long been an appealing target against cancer, but after decades of research it was consigned to the "undruggable" category.

15 Feb 2023

Promising HIV vaccine candidate by Texas Biomed stops the virus upon entry

The National Institutes of Health has awarded $3.8 million to Texas Biomedical Research Institute to further develop a promising HIV vaccine candidate that stops the virus upon entry, before it begins rapidly spreading throughout the body.

15 Feb 2023

High doses of cannabidiol may increase the effects of THC in edible cannabis products

Contrary to some common claims, a study led by Johns Hopkins Medicine researchers found that relatively high doses of cannabidiol (CBD) may increase the adverse effects of delta-9-tetrahydrocannabinol (THC), the main active ingredient in cannabis that can cause a mood alteration or a "high" sensation.

13 Feb 2023

UQ-led research effort secures almost $8 million to develop an mRNA Strep A vaccine

A University of Queensland-led research effort to develop an mRNA vaccine against Group A Streptococcus (Strep A) has secured almost $8 million in philanthropic funding.

10 Feb 2023

Study identifies a previously unknown role of 'natural killer' immune cells

Melbourne researchers have improved our understanding of how the immune system is regulated to prevent disease, identifying a previously unknown role of 'natural killer' (NK) immune cells.

10 Feb 2023

New strategies to beat rare tumors of the adrenal gland

Only one in 100,000 people suffer from a pheochromocytoma, a tumor of the adrenal gland. If the tumor has already metastasized, a radioactive compound can be used to detect malignant cells that have spread to other parts of the body, and to irradiate them from the inside.

9 Feb 2023

Preclinical News and Research

First fully human ovarian organoids provide insights about female reproductive health and disease

Ketamine appears to hold promise in treating cocaine-use disorders

Spinal cord stimulation technology instantly improves arm and hand mobility in stroke patients

UTHSC researchers secure $308,000 grant from Department of Defense for dementia study

Ferroptosis could be the key to making effective immunotherapies against liver cancer

LLNL licensee and collaborators develop novel medicines to combat autoimmune diseases

Beckman Coulter Life Sciences presenting at SLAS2023

An oral and on-demand male contraceptive

CHLA researchers receive funding to support studies into diffuse intrinsic pontine glioma

Inventia Life Science collaborates with MSD to develop 3D advanced cell models for neurodegenerative disease drug discovery

Protein degradation approach can be used to hit an ‘undruggable’ target against cancer

Promising HIV vaccine candidate by Texas Biomed stops the virus upon entry

High doses of cannabidiol may increase the effects of THC in edible cannabis products

UQ-led research effort secures almost $8 million to develop an mRNA Strep A vaccine

Study identifies a previously unknown role of 'natural killer' immune cells

New strategies to beat rare tumors of the adrenal gland

Using Webinars to Tell Science Stories – PART II

Using Webinars to Tell Science Stories – PART I

A review of innate immunity relevant to SARS-CoV-2 and COVID-19

The safety profile and the actual known adverse effects of COVID-19 vaccines in at-risk and healthy individuals

New Approach Methodologies, the 3Rs and Multimodal Imaging in Preclinical Research - eBook eBook

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