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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Tagomics announces a multiomic profiling co-marketing agreement with Agilent

Tagomics Ltd., a pioneering biomarker discovery and diagnostics company, today announced it has entered into a strategic co-marketing agreement with Agilent Technologies, a leading tools provider in the genomics sector.

From Tagomics Ltd. 26 Nov 2024

Unmasking the secrets of bacterial DNA supercoiling

Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Centre have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic target.

26 Nov 2024

New AI model tailors phage treatment for resistant bacterial infections

With the rapid development of antibiotics in the 1930s, phage therapy – using viruses known as bacteriophages or phages to tackle bacterial infections – fell into oblivion.

25 Nov 2024

Study reveals the secret to cellular youth may lie in nucleolus size

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators.

25 Nov 2024

Groundbreaking research sheds light on mitochondrial DNA depletion syndrome

Mitochondrial DNA depletion syndrome (MTDPS) is a rare genetic disorder characterized by a marked decrease in mitochondrial DNA (mtDNA).

25 Nov 2024

Groundbreaking method profiles gene activity in the living brain

A groundbreaking method to profile gene activity in the living human brain has been developed by researchers at FutureNeuro, the Research Ireland Centre for Translational Brain Science and RCSI University of Medicine and Health Sciences, in collaboration with international partners.

25 Nov 2024

UChicago scientists develop a new approach to study snoRNAs

Dynamic, reversible modifications of DNA and RNA regulate how genes are expressed and transcribed, which can influence cellular processes, disease development, and overall organismal health.

23 Nov 2024

New study challenges the traditional view of gene switches

Some sequences in the genome cause genes to be switched on or off. Until now, each of these gene switches, or so-called enhancers, was thought to have its own place on the DNA.

22 Nov 2024

Gene variant linked to early miscarriages identified

In what could be a major advance in understanding the genetic causes underlying human infertility, scientists led by researchers from Rutgers University-New Brunswick have identified a gene variant directly tied to early miscarriages in women.

22 Nov 2024

Study sheds light on how cells repair damaged DNA

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells.

22 Nov 2024

New study unveils why glioblastoma becomes resistant to treatment

A new study from scientists at the UCLA Health Jonsson Comprehensive Cancer Center helps explain why glioblastoma, one of the most aggressive forms of brain cancer, becomes resistant to treatment, and introduces a new approach that paves the way for more personalized treatment strategies for patients with this deadly brain tumor.

22 Nov 2024

Exploring how biological clocks measure aging and predict mortality

This review was published by Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), in Volume 16, Issue 17, titled, "A systematic review of phenotypic and epigenetic clocks used for aging and mortality quantification in humans."

21 Nov 2024

First 'blueprint' of human skeletal development offers new insights into bone formation

The first 'blueprint' of human skeletal development reveals how the skeleton forms, shedding light on the process of arthritis, and highlighting cells involved in conditions that affect skull and bone growth.

21 Nov 2024

Saliva microbes differ in pregnant women with stress and mental health symptoms

Research links oral cavity microbes to maternal mental health, revealing potential interventions during pregnancy to enhance psychological well-being.

21 Nov 2024

Rare genetic mutations in healthy women may be key to breast cancer origins

Researchers at the University of British Columbia (UBC), BC Cancer, Harvard Medical School and Memorial Sloan Kettering Cancer Center (MSK) have pinpointed what could be the early genetic origins of breast cancer - cancer-like mutations appearing in the cells of healthy women.

21 Nov 2024

CRISPR-based therapy shown to be safe, effective for people with transthyretin amyloidosis

A new type of therapy that 'edits' a gene in patients with a rare heart condition has been shown to be safe and effective, according to research from UCL and the Royal Free Hospital.

20 Nov 2024

Study identifies DNA collisions driving genetic changes in cancer

Cancer researchers at the University of Chicago and the University of California, San Francisco (UCSF) have discovered that mutations in certain genes can lead to the accumulation of DNA errors, resulting in a specific type of genetic change known as large tandem duplications (TDs) that can arise from the collision of two critical cellular processes: transcription and DNA replication.

20 Nov 2024