Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

CRISPR/Cas libraries could revolutionize drug discovery

CRISPR/Cas enables the targeted deactivation of genes by cutting DNA at pre-determined sites. This is accomplished by providing the Cas enzyme with a genetic zip code.

20 Mar 2019

New class of drugs could help treat patients diagnosed with ovarian cancer

A team of researchers across The University of Manchester have shown that a new class of drugs are able to stop ovarian cancer cells growing.

19 Mar 2019

GARDP and Evotec partner to tackle growing threat of antimicrobial resistance

The Global Antibiotic Research and Development Partnership and Evotec AG are today announcing the formation of a new strategic public-private partnership to tackle the growing threat of antimicrobial resistance.

19 Mar 2019

Bruker showcases new analytical systems and applied market solutions at Pittcon 2019

At Pittcon 2019, Bruker this week highlights new and innovative analytical systems and high-value applied market solutions for food analysis, pharma applications, materials science research and quality control, clinical and preclinical research, and advances in scientific software solutions.

From Bruker 19 Mar 2019

Latest advances and perspectives of all AI types used in pharmaceutical R&D

The advances in Artificial intelligence have successfully propagated into the many areas such as computer vision, speech recognition, and natural language processing.

19 Mar 2019

Insilico Medicine announces partnership with Master Investor

Insilico Medicine a biotechnology company specializing in the application of artificial intelligence for drug discovery, biomarker development, and aging research has announced its second year of partnership with Master Investor at the annual Master Investor Show.

From Insilico Medicine 14 Mar 2019

An Insider’s Guide to the chemagic™ Prime™ Junior Instrument

Masoud Toloue from PerkinElmer provides an overview of the chemagic Prime Junior Instrument and gives his inside tips for scientists working with nucleic acids.

From Revvity 14 Mar 2019

“Fail Fast, But More Confidently”: Developing Organoids for Drug Development and Discovery

Richard Eglen discusses the use of organoids in drug discovery, including the screening of candidate compounds for efficacy, toxicity, and pharmacokinetics.

From Corning Life Sciences 13 Mar 2019

Study uncovers potential new strategy to treat influenza A

A team of researchers from Scripps Research and Janssen Research & Development LLC has discovered an orally active small molecule that neutralizes influenza A group 1 viruses, the most common flu strains.

11 Mar 2019

ACROBiosystems opens new Innovation laboratory in Delaware

January 18, 2018, ACROBiosystems officially opened its New Innovation laboratory in the Delaware Innovation Space in Wilmington, Delaware, USA, and held a grand opening ceremony.

From ACROBiosystems 7 Mar 2019

Oxford Genetics successfully negotiates six licensing deals

Mercia Technologies PLC, the national investment group focused on the identification, creation, funding and scaling of innovative technology businesses with high growth potential from the UK regions, today announces that its portfolio company, Oxford Genetics Limited, has successfully negotiated six licensing deals for its scalable gene therapy manufacturing technologies in the last twelve months.

From OXGENE 5 Mar 2019

Newly developed bioluminescence sensors pave way for drug discovery

Canadian researchers, working in partnership with Brazilian colleagues, have developed 13 bioluminescence sensors for use in testing the effectiveness of new medical drugs in the laboratory.

2 Mar 2019

New multi-year affiliation announced to establish global center for rare diseases

The University of Oxford and University Hospitals in Cleveland, Ohio, today announced a multi-year affiliation to establish a global center for rare diseases.

1 Mar 2019

Pesticides, other environmental pollutants advance progression of ALS

While exact causes of amyotrophic lateral sclerosis (ALS) remain unknown, new research shows pesticides and other environmental pollutants advance the progression of the neurodegenerative disease.

28 Feb 2019

Breakthrough chromosome imaging could aid in development of new treatments

Chromosomes, each containing hundreds or thousands of genes, act like a detailed instruction manual for how cells should develop and behave.

28 Feb 2019

The Evolution of MDLC in the Pharmaceutical Industry

Dr Kelly Zhang outlines recent advances in multidimensional liquid chromatography (MDLC) for pharmaceutical analysis, to be discussed at Pittcon 2019.

From Pittcon 27 Feb 2019

Biophysicists visualize atomic-level dynamics of largest protein-degrading machine

Protein dynamics are essential for their functions. Protein nanomachines made of multiple protein molecules are highly dynamics during their actions on their functional targets, sometime called substrates.

26 Feb 2019

'Holy herb' (Yerba santa) identified as a potential treatment for Alzheimer’s disease

Yerba santa, also known as the ‘Holy Herb’, may have important implications for patients with Alzheimer’s disease.

22 Feb 2019

Successful testing of multi-organ "human-on-a-chip" could replace animals as test subjects

The replacement of animals as test subjects is one step closer to reality with the successful testing of multi-organ "human-on-a-chip" models to recapitulate the 28-day experiments typically used in animals to evaluate the systemic toxicity of drug and cosmetic compounds.

22 Feb 2019

Researchers use radio-telemetry to track the habitats of bottlenose dolphins

Using telemetry units in hospitals to monitor patient health is standard practice. Now, a similar approach is proving to be invaluable for dolphins, too.

22 Feb 2019