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Insulin resistance linked to increased risk of aortic stenosis

A large new population study of men over 45 indicates insulin resistance may be an important risk factor for the development of the world's most common heart valve disease – aortic stenosis (AS).

27 Nov 2024

Scientists decode ovarian aging with groundbreaking molecular atlas

Researchers unveil a comprehensive multi-omics atlas of ovarian aging, highlighting coordinated gene expression changes, mTOR signaling, and cellular communication as key to understanding fertility decline.

26 Nov 2024

Researchers explore the link between alcohol consumption and androgenetic alopecia

Androgenetic alopecia (AGA) is a common condition that affects millions of men and women worldwide.

26 Nov 2024

Researchers explore the impact of primary progressive aphasia on quality of life

Imagine gradually losing the ability to express yourself - not because you've forgotten the words, but because they simply won't come out.

26 Nov 2024

Florida’s Deloitte-run computer system cut off new moms entitled to Medicaid

In mid-May, Mandi Rokx had a 3-month-old baby and a letter from a Florida agency warning that they both would be cut from Medicaid, the health insurance program for people with low incomes or disabilities.

26 Nov 2024

Hormone therapy in early menopause proves safe but lacks cognitive benefits

Early menopausal hormone therapy neither benefits nor harms long-term cognition, offering reassurance but no protection against cognitive decline in healthy women.

26 Nov 2024

Atlas maps plasma proteins to transform disease diagnosis and treatment

Researchers have developed the most comprehensive atlas linking plasma proteins to diseases and traits in over 53,000 individuals, offering groundbreaking insights for precision medicine. This resource uncovers 168,100 protein-disease associations and identifies new therapeutic targets.

25 Nov 2024

Study reveals the secret to cellular youth may lie in nucleolus size

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators.

25 Nov 2024

Study finds bone density loss associated with levothyroxine

Levothyroxine, the second most commonly prescribed medication among older adults in the U.S., may be associated with bone loss, according to a study being presented next week at the annual meeting of the Radiological Society of North America (RSNA).

25 Nov 2024

From womb to midlife: Prenatal immune disruptions reshape memory and cognitive aging

Prenatal exposure to maternal pro-inflammatory cytokines shapes memory and immune function in offspring, with sex-specific effects emerging over 50 years.

24 Nov 2024

Prolonged standing at work linked to higher blood pressure

A Finnish study found that prolonged standing at work had a negative impact on the research participants' 24-hour blood pressure.

22 Nov 2024

Gene variant linked to early miscarriages identified

In what could be a major advance in understanding the genetic causes underlying human infertility, scientists led by researchers from Rutgers University-New Brunswick have identified a gene variant directly tied to early miscarriages in women.

22 Nov 2024

AI-designed drug ISM5939 granted IND clearance for cancer clinical trials

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, announced that it has received IND clearance from FDA for ISM5939, a potential best-in-class oral small molecule inhibitor targeting ENPP1 for the treatment of solid tumors.

22 Nov 2024

New neuroimaging marker may identify persons at risk of dementia in future clinical trials

A new neuroimaging marker of cerebral small vessel disease is related to general cognition and may serve to identify persons at risk of dementia in future clinical trials, a landmark study has found.

21 Nov 2024

Pandemic increases depression risk for older adults living with migraine

A recent longitudinal study from the University of Toronto reveals the mental health consequences of the COVID-19 pandemic on older adults living with migraine.

21 Nov 2024

Exploring how biological clocks measure aging and predict mortality

This review was published by Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), in Volume 16, Issue 17, titled, "A systematic review of phenotypic and epigenetic clocks used for aging and mortality quantification in humans."

21 Nov 2024

Study predicts major rise in deaths due to extreme temperatures and air pollution

New study projects a sharp rise in temperature- and pollution-related mortality, with the impact of temperature surpassing that of pollution for a fifth of the global population.

21 Nov 2024

Study links prenatal immune activity to Alzheimer's risk in later life

Findings from a Mass General Brigham-led study that has followed participants since before birth may offer clues about the origins of Alzheimer's disease.

21 Nov 2024

Study links historical education policies to better cognitive outcomes later in life

Historical policies shaping educational attainment have enduring benefits for later life memory and risk of dementia, according to a study led by a Rutgers Health researcher.

21 Nov 2024

Jaw muscle size linked to sarcopenia risk in older adults

As populations age, the prevalence of sarcopenia - a progressive loss of muscle mass and function - has become an increasingly urgent public health concern. Sarcopenia increases the risk of falls and frailty, reduces the quality of life for older adults, and heightens the likelihood of requiring long-term care. Preventing sarcopenia is, therefore, crucial for alleviating this healthcare burden.

20 Nov 2024