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Personalizing CAR-T cell stimulation during manufacturing can enhance its functionality

New adoptive T cell therapies -; in which T cells, the immune system's natural hunters patrolling the body for foreign adversaries, are retrieved from cancer-riddled patients, super-charged and amplified outside the body, and then infused back into the same patient -; are changing the prospects of cancer patients.

10 Feb 2023

Bread made from whole cell pulse flour simulates satiety hormones to help us feel full

Bread made from a new type of whole cell pulse flour can lower blood glucose (sugar) levels and keep you fuller for longer, new research has found.

10 Feb 2023

Molecular switch regulates autophagy in plants

Autophagy, or "self-eating", is an essential cellular quality control mechanism that clears the cell of protein aggregates and damaged organelles. This mechanism is inactive under normal conditions and only triggered upon persistent cellular stress.

10 Feb 2023

Longitudinal assessment of gastrointestinal virome of mothers and infants

In a recent study published in Cell Host & Microbe, researchers comparatively assessed the gastrointestinal virome of mothers and infants.

10 Feb 2023

Researchers gain new insights into the development of drug-resistant mutant lineages of cells

A deeper understanding of how tumor cells respond to treatment is vital to improving the effectiveness of therapies for diseases such as cancer.

10 Feb 2023

Is gut microbiome lipid metabolism a determinant of human health?

Researchers highlighted the role of lipids, especially bacteria-derived lipids in the gut microbiome, in mammalian physiology in the context of immunity and metabolism. Note that commensal fungal species also produce lipid metabolites.

10 Feb 2023

New method for capturing moments during protein translation

Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like gene regulation has been greatly enhanced by the development of a process termed PETEOS—short for peptidyl-tRNA enrichment using organic extraction and silica adsorption.

10 Feb 2023

Multi-omics approach uncovers gut microbiome-host interactions in myalgic encephalomyelitis/chronic fatigue syndrome patients

Researchers performed a multi-omics investigation of gut microbiome-host interactions and plasma metabolomics among myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) patients.

10 Feb 2023

Casein-based diet found to protect diabetic mice against autoimmunity

Researchers studied diet-commensal microbial interactions in autoimmunity.

10 Feb 2023

Can lifestyle and nutrition be the answer for metabolic syndrome and type 2 diabetes remission?

Recently, scientists have reviewed the existing literature to elucidate the root cause of metabolic syndrome and type 2 diabetes.

10 Feb 2023

New compound limits the replication of influenza viruses

Viruses use the molecular repertoire of the host cell to replicate. Researchers from the Cluster of Excellence ImmunoSensation2 at the University of Bonn, together with Japanese researchers, want to exploit this for the treatment of influenza.

9 Feb 2023

Scientists discover a protein in the lung that blocks SARS-CoV-2 infection

University of Sydney scientists have discovered a protein in the lung that blocks SARS-CoV-2 infection and forms a natural protective barrier in the human body.

9 Feb 2023

UVA researchers discover a key trigger for non-alcoholic fatty liver disease

University of Virginia School of Medicine researchers have discovered a key trigger for non-alcoholic fatty liver disease, a mysterious condition that causes fat to build up in the liver for no clear reason.

9 Feb 2023

Scientists find microRNAs in human pancreatic cells that are strongly linked with type 2 diabetes

In a new large-scale genetic analysis, scientists have found a set of small RNA molecules, called microRNAs, in human pancreatic cells that are strongly associated with type 2 diabetes.

9 Feb 2023

Novel COVID-19 protein component vaccine elicits durable immune response in rodents

Researchers describe a novel SARS-CoV-2 spike protein component vaccine called MT-001.

9 Feb 2023

Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection

Researchers assess the impact of COVID-19 vaccination on immune responses during a breakthrough infection.

9 Feb 2023

New Zika virus lineages show increased fitness

The current study, published in the journal PLOS Neglected Tropical Diseases, aimed to explore the possible phenotypic adaptation of the Zika virus to increase its transmissibility and virulence in the Americas.

9 Feb 2023

Study demonstrates antiviral effects of vinegar against SARS-CoV-2

A study published in the journal PLOS ONE demonstrates the effectiveness of acetic acid, the main component of vinegar, in inactivating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

9 Feb 2023

Researchers find link between fungal microbes in infant gut and body-mass index

Researchers in the Cumming School of Medicine (CSM) at the University of Calgary in collaboration with the Canadian CHILD Study have found a link between the diversity, or number, of fungal species in the infant gut and the body-mass index (BMI) of infants.

9 Feb 2023

Antibodies against SARS-CoV-2 are higher in infants than in mothers

Researchers characterize the functional and binding antibody responses against SARS-CoV-2 in postpartum women and their infected infants.

9 Feb 2023

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B Cell News and Research

Personalizing CAR-T cell stimulation during manufacturing can enhance its functionality

Bread made from whole cell pulse flour simulates satiety hormones to help us feel full

Molecular switch regulates autophagy in plants

Longitudinal assessment of gastrointestinal virome of mothers and infants

Researchers gain new insights into the development of drug-resistant mutant lineages of cells

Is gut microbiome lipid metabolism a determinant of human health?

New method for capturing moments during protein translation

Multi-omics approach uncovers gut microbiome-host interactions in myalgic encephalomyelitis/chronic fatigue syndrome patients

Casein-based diet found to protect diabetic mice against autoimmunity

Can lifestyle and nutrition be the answer for metabolic syndrome and type 2 diabetes remission?

New compound limits the replication of influenza viruses

Scientists discover a protein in the lung that blocks SARS-CoV-2 infection

UVA researchers discover a key trigger for non-alcoholic fatty liver disease

Scientists find microRNAs in human pancreatic cells that are strongly linked with type 2 diabetes

Novel COVID-19 protein component vaccine elicits durable immune response in rodents

Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection

New Zika virus lineages show increased fitness

Study demonstrates antiviral effects of vinegar against SARS-CoV-2

Researchers find link between fungal microbes in infant gut and body-mass index

Antibodies against SARS-CoV-2 are higher in infants than in mothers

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