Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

ATG14 found to be a critical defender against hepatic injury and fibrosis

Autophagy is indispensable for maintaining hepatocyte integrity, metabolic homeostasis, and survival. While several autophagy-related proteins have been studied in hepatic physiology, the specific role of Autophagy Related 14 (ATG14) in liver health has remained unclear.

24 Feb 2026

Engineers develop highly precise gene editor for safer cystic fibrosis treatments

Engineers at the University of Pennsylvania and Rice University have refined a technology for editing individual genetic "base pairs" to a new level of precision, opening the door to safer, more reliable therapies for a wide range of genetic diseases, and to potential treatments for some cystic fibrosis patients that may yield better outcomes than existing therapies.

23 Feb 2026

High-cost rare disease drugs challenge Norwegian health priorities

New medical developments make it possible to treat an increasing number of severe and rare diseases with novel, high-cost pharmaceuticals.

19 Feb 2026

Young adults with complex conditions face Medicaid coverage disruptions at age 19

In most states, Medicaid eligibility rules shift at age 19, when individuals transition from child to adult classification.

18 Feb 2026

New gene editing approach offers hope for cystic fibrosis patients

UCLA researchers have developed a lipid nanoparticle-based gene-editing approach capable of inserting an entire healthy gene into human airway cells, restoring key biological function in a laboratory model of cystic fibrosis and establishing a potential new path toward mutation-agnostic gene therapy for inherited lung diseases.

17 Feb 2026

Study identifies distinctive feature of tissues from young patients with colorectal cancer

A study co-led by University of Texas at Dallas bioengineers identified a distinctive feature of tissues from young patients diagnosed with colorectal cancer, a disease that typically affects older patients.

17 Feb 2026

Insilico Medicine and MSK collaborate to discover new drug targets for gastroesophageal malignancies

Insilico Medicine ("Insilico", 3696.HK), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, and Memorial Sloan Kettering Cancer Center (MSK) have entered into a collaborative research agreement aimed at discovering new therapeutic targets for gastroesophageal malignancies.

17 Feb 2026

Do cocoa flavanols influence heart and fatty liver risk factors?

A recent Nutrients review examined whether cocoa-rich dark chocolate influences cardiovascular and metabolic dysfunction-associated steatotic liver disease risk factors through antioxidant, anti-inflammatory, and endothelial effects. Evidence suggests modest improvements in biomarkers, but most data come from short-term studies, so definitive clinical benefits remain unproven.

16 Feb 2026

Study explores whether a bidirectional causal link exists between MASLD and sarcopenia

Metabolic dysfunction-associated steatotic liver disease (MASLD) and sarcopenia frequently coexist, yet their causal relationship and underlying mechanisms remain poorly defined.

13 Feb 2026

Review links betel nut addiction to cancer, heart disease, and metabolic risks

This review examines the epidemiology, health risks, neurobiological mechanisms, and emerging treatments related to betel nut addiction worldwide. It highlights strong links with oral cancer, cardiometabolic disease, and addiction pathways while noting limited established therapies and the need for coordinated public health strategies.

11 Feb 2026

Choroid plexus enlargement in Long COVID signals cognitive risk

The increased size of, and lesser blood supply to, a key brain structure in patients with Long COVID tracks with known blood markers of Alzheimer's disease and greater levels of dementia, a new study finds.

10 Feb 2026

Influenza viruses can directly impair heart function

Mount Sinai researchers have identified a cellular mechanism linking infections from influenza A viruses (IAVs) to cardiovascular disease, providing critical insights on how influenza can damage the heart and increase the risk of a heart attack or other major cardiovascular event.

9 Feb 2026

Single-cell study uncovers cardiomyocyte-fibroblast signaling in ischemia-reperfusion injury

Announcing a new article publication for BIO Integration journal. Cardiac cell death and myocardial fibrosis after ischemia-reperfusion (I/R) injury are the primary causes of impaired cardiac function.

6 Feb 2026

Artificial lung keeps patient alive after lung removal

Researchers evaluate the effectiveness of a novel extracorporeal total artificial lung system to enable bilateral pneumonectomy in patients with severe ARDS.

5 Feb 2026

Engineered liver tissue model mimics early metabolic liver disease

More than 100 million people in the United States suffer from metabolic dysfunction-associated steatotic liver disease (MASLD), characterized by a buildup of fat in the liver.

3 Feb 2026

Dickkopf 3 protein drives radiation-induced fibrosis and chronic skin damage

The protein Dickkopf 3 plays a key role in the development of radiation-induced fibroses - and could be a promising target for novel therapies.

3 Feb 2026

Updated newborn screening guidelines aim to improve cystic fibrosis detection

An updated report on cystic fibrosis (CF) from Ann & Robert H. Lurie Children's Hospital of Chicago, in partnership with the Cystic Fibrosis Foundation and funded by the Centers for Disease Control and Prevention (CDC), highlights the new national guidelines on CF newborn screening that aim to detect affected babies earlier, more accurately and more fairly.

1 Feb 2026

Young adults with complex childhood conditions experience longer hospital stays, higher readmissions

Young adults with complex chronic childhood-onset conditions such as sickle cell disease and cystic fibrosis experience longer hospital stays, higher readmission rates and greater use of resources in adult hospitals, according to a new study in JAMA Network Open.

29 Jan 2026

"Artificial lungs" keep a patient alive until a double lung transplantation was available

Humans can't live without lungs. But Ankit Bharat's patient did for 48 hours.

29 Jan 2026

Insilico Medicine and Qilu Pharmaceutical partner to develop AI-designed cardiometabolic drugs

Insilico Medicine, a clinical-stage biotechnology company powered by generative AI, and Qilu Pharmaceutical Group, a major comprehensive modern pharmaceutical enterprise in China, as well as its subsidiary Shanghai Qilu Pharmaceutical Research Center, today announced a strategic partnership on innovative drug development, leveraging Insilico's proprietary Pharma.AI platform to jointly develop small molecule inhibitors, focusing on specific targets for cardiometabolic disease management.

27 Jan 2026

Fibrosis News and Research

Further Reading

ATG14 found to be a critical defender against hepatic injury and fibrosis

Engineers develop highly precise gene editor for safer cystic fibrosis treatments

High-cost rare disease drugs challenge Norwegian health priorities

Young adults with complex conditions face Medicaid coverage disruptions at age 19

New gene editing approach offers hope for cystic fibrosis patients

Study identifies distinctive feature of tissues from young patients with colorectal cancer

Insilico Medicine and MSK collaborate to discover new drug targets for gastroesophageal malignancies

Do cocoa flavanols influence heart and fatty liver risk factors?

Study explores whether a bidirectional causal link exists between MASLD and sarcopenia

Review links betel nut addiction to cancer, heart disease, and metabolic risks

Choroid plexus enlargement in Long COVID signals cognitive risk

Influenza viruses can directly impair heart function

Single-cell study uncovers cardiomyocyte-fibroblast signaling in ischemia-reperfusion injury

Artificial lung keeps patient alive after lung removal

Engineered liver tissue model mimics early metabolic liver disease

Dickkopf 3 protein drives radiation-induced fibrosis and chronic skin damage

Updated newborn screening guidelines aim to improve cystic fibrosis detection

Young adults with complex childhood conditions experience longer hospital stays, higher readmissions

"Artificial lungs" keep a patient alive until a double lung transplantation was available

Insilico Medicine and Qilu Pharmaceutical partner to develop AI-designed cardiometabolic drugs

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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