Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

Depression-like behavior may accelerate endocrine aging in primates

A new review was published in Volume 18 of Aging on June 11, 2026, titled "Age-related dysfunctions of the neuroendocrine axes in nonhuman primates with depression-like and anxious behavior."

1 Jul 2026

Flavonoid-rich foods may blunt breast cancer risk tied to genetics

Higher flavodiet scores were associated with lower breast cancer risk among 93,271 UK Biobank females followed for a median of 11.8 years. The inverse association was particularly evident in women with high genetic risk, but the observational study cannot prove causation.

1 Jul 2026

Scientists map how chronic stress alters somatostatin levels in the brain

Consider the brake. Not the engine, which gets all the attention, but the brake, the quiet thing that decides how fast a system is allowed to go.

1 Jul 2026

Experts reframe steatotic liver disease as a dynamic continuum

The classification of steatotic liver disease (SLD) is undergoing a major conceptual transformation. In a recent article published in eGastroenterology, Dr. Chen, Dr. Horn, and Prof. Tacke from Charité - Universitätsmedizin Berlin argue that metabolic dysfunction-associated steatotic liver disease (MASLD), metabolic dysfunction and alcohol-associated liver disease (MetALD), and alcohol-associated liver disease (ALD) should not be regarded as rigid diagnostic categories, but rather as interconnected and evolving disease trajectories.

30 Jun 2026

Simple blood test could identify the most effective obesity drug

Fasting blood tests measuring GLP-1 and GIP levels may predict obesity treatment response to semaglutide and tirzepatide, enhancing personalized therapy.

29 Jun 2026

Breastfeeding linked to longer sleep duration in one year old infants

The World Health Organization (WHO) recommends exclusive breastfeeding for the first six months of life because of its many proven benefits, including protection against infections and support for healthy long-term development.

26 Jun 2026

Unexplained skin darkening leads to life-saving Addison's disease diagnosis

A 24-year-old woman presented with two years of unexplained darkening of her hands, feet, gums, and tongue.

26 Jun 2026

Longer hormone exposure linked to healthier brain aging in women

Research indicates that hormonal therapies and later menopause are associated with increased brain volume and thickness, promoting healthier aging.

26 Jun 2026

Neuroticism and adversity dominate depression and anxiety risk in UK Biobank study

In a UK Biobank study of 87,648 adults followed for 13.7 years, psychosocial factors accounted for the largest estimated population burden of depression and anxiety in both women and men. Neuroticism symptoms, childhood and adult adversity, obesity, chronic inflammation, and some reproductive factors in women were linked to incident mental health outcomes, although the PAF estimates remain theoretical and not proof of causality.

25 Jun 2026

Gut microbes emerge as potential players in estrogen-driven cancers

A new review maps how the endocrine-microbiome axis expands the estrobolome concept, showing that gut microbes may alter estrogen recycling, produce hormone-like metabolites, and shape inflammation and tissue environments in hormone-driven cancers. Human evidence remains mostly associative, so the authors call for causal models, longitudinal multi-omics, multi-kingdom profiling, and sex-stratified studies before microbiome-guided cancer strategies enter routine care.

25 Jun 2026

Blood metabolites reveal lifestyle links to brain health before dementia

Blood metabolome profiling in dementia-free middle-aged adults linked 14 metabolites to cognition and 22 metabolites to MRI markers of brain health. Lifestyle, clinical factors, medication use and gut microbiota appeared to shape many of these metabolites, with ergothioneine emerging as a notable cognition-linked signal.

25 Jun 2026

Chronic stress helps tumors evade immune attack through gut microbes

Chronic psychological stress can help tumors evade immune attack through a chain of molecular events involving gut bacteria and viruses within those bacteria, according to a study led by Weill Cornell Medicine investigators.

25 Jun 2026

FDA approves palbociclib combination for advanced HR-positive HER2-positive breast cancer

Today, Alliance Foundation Trials, LLC (AFT) was informed that the U.S. Food and Drug Administration has approved palbociclib in combination with trastuzumab, with or without pertuzumab, and endocrine therapy for adult patients with hormone receptor–positive (HR+), human epidermal growth factor receptor 2–positive (HER2+) locally advanced or metastatic breast cancer following induction treatment.

24 Jun 2026

New oral drug shows promise for chronic heart failure treatment

An early clinical study shows that a new oral drug is safe and well-tolerated in patients with chronic heart failure.

24 Jun 2026

Immunotherapy may help women with early ovarian insufficiency to conceive babies

A pilot study from Karolinska Institutet shows that immunotherapy may enable stimulation of egg maturation in women with autoimmune POI (premature ovarian insufficiency) – a condition that usually leads to infertility.

24 Jun 2026

Eating 90 g of wholegrains daily linked to lower breast cancer risk

Research indicates that long-term wholegrain intake per Nordic guidelines is associated with reduced breast cancer risk, emphasizing food type differences.

24 Jun 2026

USC study links modified Mediterranean diet to longer lifespan

A plant- and fish-based, low-protein diet paired with small amounts of an amino acid commonly found in eggs, meat and dairy increased healthy lifespan and decreased frailty and fat mass in mice, according to a new USC study published today in the journal Cell Metabolism.

23 Jun 2026

Lifetime estrogen exposure linked to improved brain health in women

Researchers from the University of Kansas have shown a link between reproductive hormone exposure throughout life and brain health in 459 women aged 65 to 80.

23 Jun 2026

Artificial intelligence helps breast cancer patients avoid unnecessary chemotherapy

Research led by RCSI University of Medicine and Health Sciences and University College Dublin (UCD) has identified immune markers that could help doctors more accurately determine which breast cancer patients are unlikely to benefit from chemotherapy, potentially sparing some patients from unnecessary treatment.

23 Jun 2026