Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Timing, type, and frequency of exercise are crucial components for optimal glycemic control in type 2 diabetes

Exercise plays a crucial role in managing type 2 diabetes, offering potential benefits such as improved glycemic control. This study explores exercise recommendations and their impact on dietary, medication, and behavioral factors for optimal diabetes care.

5 Jul 2023

Researchers uncover the role of glutaminase 2 in glucose homeostasis

Glutaminase 2 (GLS2) is a master regulator of glutaminolysis. GLS2 converts glutamine to glutamate, thereby playing a role in cellular energy production. GLS2 is abundant in the liver, and is also found in pancreatic β-cells. However, the role of GLS2 in pancreatic islets – in which both ɑ- and β- cells are present – associated with glucose metabolism is currently unknown.

5 Jul 2023

Study examines how B cells affect the development of PCOS

Polycystic ovary syndrome (PCOS) is a common hormone disorder in women. Studies have shown that the change in hormones is accompanied by variations in immunological B cells.

5 Jul 2023

Reproductive impact of changes in the vaginal microbiome of obese women

Study explores the impact of obesity on vaginal microbiota and reproduction.

5 Jul 2023

Fit to beat diabetes: mendelian randomization study confirms the power of exercise

Researchers investigated the causality of the relationship between cardiorespiratory fitness and diabetes mellitus type 2.

5 Jul 2023

Growth factor study reveals potential breakthrough in obesity management

Study discusses the effects of a growth factor that showed promising results in mice in an obesity trial.

4 Jul 2023

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

Activation of the NRF2 transcription factor shows promise as a potential treatment approach for non-alcoholic fatty liver disease (NAFLD), a condition associated with oxidative stress and liver damage. By screening FDA-approved drugs, researchers identified six compounds that enhanced NRF2 activity and demonstrated protective effects against oxidative stress and lipid accumulation.

3 Jul 2023

A new law is supposed to protect pregnant workers — but what if we don’t know how?

Vanessa Langness had always been a bit worried about the chemicals she worked with as a biomedical researcher, but when she got pregnant in October, her concerns grew.

30 Jun 2023

Higher lean muscle mass may offer protection against Alzheimer's disease

High levels of lean muscle might protect against Alzheimer's disease, suggests a large study published in the open access journal BMJ Medicine.

29 Jun 2023

The protective effects of extra virgin olive oil on disease risk factors

Researchers conducted a systematic review to consolidate recent evidence on the preventive benefits of extra virgin olive oil on disease risk factors.

29 Jun 2023

Study provides a comprehensive summary of benefits of exercise for people with Type 2 diabetes

An analysis on the positive effects of exercise on blood sugar levels in people with Type 2 diabetes shows that while all exercise helps, certain activities – and their timing – are extremely good for people's health.

28 Jun 2023

BMI cutoff for shoulder replacement surgery could lead to health disparities, MUSC surgeon warns

In June, the American Medical Association announced a new policy that encourages physicians not to focus solely on body mass index, or BMI, as a determinant of weight and health.

28 Jun 2023

Study challenges link between added sugar intake and prediabetes risk

Researchers evaluate the association between total added sugar intake and prediabetes risk.

22 Jun 2023

Study reveals contrasting effects of sucralose on insulin and glucose control

Sucralose, a commonly used artificial sweetener, has contrasting effects on insulin secretion and glucose homeostasis. While bolus administration of sucralose enhances insulin secretion and decreases glucose levels, long-term consumption exacerbates insulin resistance and glucose intolerance, particularly in combination with a high-fat diet. The study highlights the involvement of the T1R3-ERK1/2 pathway in sucralose-induced insulin resistance in the liver.

22 Jun 2023

Study reveals how metformin interacts with the liver and gut to reduce circulating glucose levels

There are still many enigmas about the mechanism of action of metformin, the most prescribed drug to treat diabetes mellitus, also known as type 2 diabetes.

22 Jun 2023

Rare sugars in a diabetic diet: the efficacy of a D-allulose-containing diet in patients with type two diabetes

Researchers evaluated the effectiveness of diabetic diets containing D-allulose among type 2 diabetes patients.

21 Jun 2023

New study reveals the hidden mechanism between cancer and diabetes

Back in the 1920s, researchers discovered that cancer patients had sweet-smelling urine. First, the doctors were puzzled, but they soon realised that it was a result of elevated blood sugar levels.

20 Jun 2023

Diet alone not the sole culprit: Unraveling the complexities of metabolic disease rise in the U.S.

In a study published in the journal Pharma Nutrition, scientists have explored the long-term impact of Western diet and lifestyle factors on the risk of metabolic disease in the United States.

19 Jun 2023

Breastfeeding can protect mothers against type 2 diabetes in later years

Breastfeeding can improve the number of insulin-producing cells in the pancreas and increase insulin sensitivity in mothers, helping to protect them against type 2 diabetes in later years, suggests a mice study presented Thursday at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill.

15 Jun 2023

Understanding the developmental link: vitamin D's role in metabolic disease risk

Study showed that transplanting fetal hematopoietic stem cells exposed to vitamin D deficiency induces diabetes.

14 Jun 2023

Insulin Resistance News and Research

Further Reading

Timing, type, and frequency of exercise are crucial components for optimal glycemic control in type 2 diabetes

Researchers uncover the role of glutaminase 2 in glucose homeostasis

Study examines how B cells affect the development of PCOS

Reproductive impact of changes in the vaginal microbiome of obese women

Fit to beat diabetes: mendelian randomization study confirms the power of exercise

Growth factor study reveals potential breakthrough in obesity management

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

A new law is supposed to protect pregnant workers — but what if we don’t know how?

Higher lean muscle mass may offer protection against Alzheimer's disease

The protective effects of extra virgin olive oil on disease risk factors

Study provides a comprehensive summary of benefits of exercise for people with Type 2 diabetes

BMI cutoff for shoulder replacement surgery could lead to health disparities, MUSC surgeon warns

Study challenges link between added sugar intake and prediabetes risk

Study reveals contrasting effects of sucralose on insulin and glucose control

Study reveals how metformin interacts with the liver and gut to reduce circulating glucose levels

Rare sugars in a diabetic diet: the efficacy of a D-allulose-containing diet in patients with type two diabetes

New study reveals the hidden mechanism between cancer and diabetes

Diet alone not the sole culprit: Unraveling the complexities of metabolic disease rise in the U.S.

Breastfeeding can protect mothers against type 2 diabetes in later years

Understanding the developmental link: vitamin D's role in metabolic disease risk

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